Relevance. Chemical burns to the eye are a significant clinical problem that can seriously affect patients’ vision and quality of life. Research points to the need to develop effective treatment and prevention methods. In the United States, approximately 15,865 new cases are reported annually, highlighting the importance of this problem. Purpose of the study. To determine the effectiveness of photodynamic therapy (PDT) using a pulsed red laser and the use of Vixipin in the treatment of chemical eye burns of various etiologies and severity. Materials and methods. The study involved 60 patients (60 eyes) with I, II and III degrees of burn severity, examined in the period 2020–2023. on the basis of the Tashkent Medical Academy. Depending on the therapy, patients were divided into three groups: control group, main group I (who received PDT) and main group II (who received PDT and Vixipin). Results and conclusion. Treatment resulted in a significant reduction in symptoms in all patients. In the second main group, the duration of hospital stay was reduced to 7 days, and in the first main group to 8.5 days. Biochemical changes in tear fluid showed decreased levels of nitric oxide (NO) and malondialdehyde (MDA), indicating decreased oxidative stress and inflammation. The addition of PDT and Vixipin to traditional therapy significantly improves the outcome of treatment of chemical eye burns, reducing the duration of treatment and reducing the risk of complications. The results confirm the need for further study and implementation of these methods in clinical practice.
| Mualliflar | Ф. А. Бахритдинова, Э. Н. Билалов, Миррахимова С. Ш., К. И. Нарзикулова, Назирова С. Х. |
|---|---|
| Jurnal | Передовая Офтальмология |
| Nashr sanasi | 2024-06-19 |
| Jild | 8 |
| Son | 2 |
| Betlar | 19-25 |
| Til | ru |
| DOI | 10.57231/j.ao.2024.8.2.003 |
DOI: 10.57231/j.ao.2024.8.2.003 · Maqolaning asl sahifasi · PDF
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