MODERN MULTIMODAL APPROACHES TO THE DIAGNOSIS AND TREATMENT OF PRIMARY BRAIN TUMORS

Mamadaliev Abduraxmon Mamatkulovich

Research Focus · 2026-yil

Annotatsiya

Primary brain tumors represent a heterogeneous group of neoplasms with high clinical and social significance. Neuroepithelial tumors, particularly glial neoplasms, account for the majority of intracranial tumors and are characterized by aggressive biological behavior, high recurrence rates, and limited long-term survival despite advances in therapy. Modern diagnostic strategies rely heavily on neuroimaging modalities, primarily magnetic resonance imaging and computed tomography, with increasing interest in hybrid techniques combining MRI and positron emission tomography. Contemporary treatment paradigms are based on multimodal approaches integrating microsurgical resection, radiotherapy, chemotherapy, and emerging immunotherapeutic strategies. Radiotherapy remains a cornerstone of treatment for malignant central nervous system tumors, with fractionated regimens demonstrating optimal tumor control while minimizing neurocognitive toxicity. Advances in stereotactic radiosurgery and neuronavigation have significantly improved treatment precision and outcomes. Nevertheless, prognosis for high-grade gliomas remains poor, underscoring the need for personalized therapeutic strategies and further research into innovative treatment modalities.

Maqola ma’lumotlari
MualliflarMamadaliev Abduraxmon Mamatkulovich
JurnalResearch Focus
Nashr sanasi2026-01-05
Jild4
Son12
Betlar199-203
TilIngliz

Kalit so‘zlar

brain tumors, gliomas, radiotherapy, multimodal treatment, stereotactic radiosurgery

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