Oxidative stress and fertility indicators associated with varicocele in men of reproductive age

Muhammadqodir Arabboyev Dilshod oʻgʻli, Dilmurod Egamberdiyev Kamolitdinovich, Мухаммадкодир Араббоев Дилшод угли, Дилмурод Эгамбердиев Камолитдинович, Muhammadqodir Arabboyev Dilshod oʻgʻli, Dilmurod Egamberdiyev Kamolitdinovich

Research Focus · 2026-yil

Annotatsiya

Varicocele is a widespread venous anatomical anomaly in men of reproductive age which leads to impaired spermatogenesis and an increased risk of infertility. This pathology is characterised by dilatation of the pampiniform plexus and the testicular veins. Oxidative stress is considered one of the main pathophysiological mechanisms associated with varicocele. Excessive formation of reactive oxygen species (ROS) and insufficiently effective functioning of the antioxidant system lead to damage to the membrane and DNA structure of spermatozoa. Lipid peroxidation, protein oxidation and damage to genetic material result in a decrease in the number, motility and normal morphology of spermatozoa. At the molecular level, oxidative stress damages Leydig cells, reduces testosterone biosynthesis and disrupts spermatogenesis under conditions of testicular hypoxia. This article describes the scientifically substantiated relationships between varicocele, oxidative stress and fertility indicators.

Maqola ma’lumotlari
MualliflarMuhammadqodir Arabboyev Dilshod oʻgʻli, Dilmurod Egamberdiyev Kamolitdinovich, Мухаммадкодир Араббоев Дилшод угли, Дилмурод Эгамбердиев Камолитдинович, Muhammadqodir Arabboyev Dilshod oʻgʻli, Dilmurod Egamberdiyev Kamolitdinovich
JurnalResearch Focus
NashriyotВетеринария ИТИ ва “Илм-фан ва инновациялар академияси” МЧЖ
ISSN2181-3833
Nashr sanasi2026-01-05
Jild4
Son12
Betlar219-225
TilIngliz
Ilmiy sohaVeterinariya
DOI10.66073/researchfocus.v4i12.1931
Indeksga qo‘shilgan2026-09-12

DOI: 10.66073/researchfocus.v4i12.1931 · Maqolaning asl sahifasi

Kalit so‘zlar

варикоцеле, окислительный стресс, активные формы кислорода, сперматогенез, повреждение ДНК сперматозоидов, перекисное окисление липидов, антиоксиданты, varikotsele, oksidativ stress, aktiv kislorod turlari, spermatogenez, spermatozoid DNK shikastlanishi, lipid peroksidlanish, antioksidantlar, varicocele, oxidative stress, reactive oxygen species, spermatogenesis, sperm DNA damage, lipid peroxidation, antioxidants

Ilmiy soha

Veterinariya

Iqtibos keltirish

APAMuhammadqodir Arabboyev Dilshod oʻgʻli, Dilmurod Egamberdiyev Kamolitdinovich, Мухаммадкодир Араббоев Дилшод угли, Дилмурод Эгамбердиев Камолитдинович, Muhammadqodir Arabboyev Dilshod oʻgʻli, & Dilmurod Egamberdiyev Kamolitdinovich (2026). OXIDATIVE STRESS AND FERTILITY INDICATORS ASSOCIATED WITH VARICOCELE IN MEN OF REPRODUCTIVE AGE. Research Focus, 4(12), 219-225. https://doi.org/10.66073/researchfocus.v4i12.1931
GOST (OAK)Muhammadqodir Arabboyev Dilshod oʻgʻli va b. OXIDATIVE STRESS AND FERTILITY INDICATORS ASSOCIATED WITH VARICOCELE IN MEN OF REPRODUCTIVE AGE // Research Focus. – 2026. – T. 4, № 12. – P. 219-225. – DOI: 10.66073/researchfocus.v4i12.1931.
MLAMuhammadqodir Arabboyev Dilshod oʻgʻli, Dilmurod Egamberdiyev Kamolitdinovich, Мухаммадкодир Араббоев Дилшод угли, Дилмурод Эгамбердиев Камолитдинович, Muhammadqodir Arabboyev Dilshod oʻgʻli, and Dilmurod Egamberdiyev Kamolitdinovich. “OXIDATIVE STRESS AND FERTILITY INDICATORS ASSOCIATED WITH VARICOCELE IN MEN OF REPRODUCTIVE AGE.” Research Focus, 4(12), 219-225, 2026. https://doi.org/10.66073/researchfocus.v4i12.1931
ChicagoMuhammadqodir Arabboyev Dilshod oʻgʻli, Dilmurod Egamberdiyev Kamolitdinovich, Мухаммадкодир Араббоев Дилшод угли, Дилмурод Эгамбердиев Камолитдинович, Muhammadqodir Arabboyev Dilshod oʻgʻli, and Dilmurod Egamberdiyev Kamolitdinovich. “OXIDATIVE STRESS AND FERTILITY INDICATORS ASSOCIATED WITH VARICOCELE IN MEN OF REPRODUCTIVE AGE.” Research Focus, 4(12), 219-225 (2026). https://doi.org/10.66073/researchfocus.v4i12.1931
HarvardMuhammadqodir Arabboyev Dilshod oʻgʻli, Dilmurod Egamberdiyev Kamolitdinovich, Мухаммадкодир Араббоев Дилшод угли, Дилмурод Эгамбердиев Камолитдинович, Muhammadqodir Arabboyev Dilshod oʻgʻli, and Dilmurod Egamberdiyev Kamolitdinovich (2026) ‘OXIDATIVE STRESS AND FERTILITY INDICATORS ASSOCIATED WITH VARICOCELE IN MEN OF REPRODUCTIVE AGE’, Research Focus, 4(12), 219-225. https://doi.org/10.66073/researchfocus.v4i12.1931
BibTeX
@article{muhammadqodirarabboyevdilshodogli2026,
  title = {OXIDATIVE STRESS AND FERTILITY INDICATORS ASSOCIATED WITH VARICOCELE IN MEN OF REPRODUCTIVE AGE},
  author = {Muhammadqodir Arabboyev Dilshod oʻgʻli and Dilmurod Egamberdiyev Kamolitdinovich and Мухаммадкодир Араббоев Дилшод угли and Дилмурод Эгамбердиев Камолитдинович and Muhammadqodir Arabboyev Dilshod oʻgʻli and Dilmurod Egamberdiyev Kamolitdinovich},
  journal = {Research Focus},
  year = {2026},
  volume = {4},
  number = {12},
  pages = {219-225},
  doi = {10.66073/researchfocus.v4i12.1931},
  url = {https://doi.org/10.66073/researchfocus.v4i12.1931}
}

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