Local Anesthesia and Conduction Anesthesia

Makhmudovna, Zulfiya, Buzrukzoda , Javohir

Мактабгача ва мактаб таълими · 2026-yil

Annotatsiya

This study is devoted to the characterization of popular local anesthetics and the determination of the mosteffective drugs for local anesthesia. The authors conducted a review of current scientific publications examining theproperties of local anesthetics, their pharmacokinetic and pharmacodynamic characteristics, as well as methods of application.The study was carried out in two directions: using traditional printed sources and online databases. The collecteddata allowed for a comparative analysis of the medications, taking into account their beneficial properties and potentialside effects. As a result of this analysis, the drug with the optimal balance of favorable characteristics was identified.During the research, key criteria determining the choice of the drug were identified: efficacy, duration of the latent period,duration of action, and level of toxicity. To perform local anesthesia during a surgical intervention, an anesthetic withhigh efficacy and a rapid onset of action (short latency time) is required. It is essential that the anesthetic provide a longlastinganalgesic effect, allowing for a single administration even during prolonged surgery while maintaining low toxicity.Seven local anesthetics were analyzed in the study: procaine (novocaine), lidocaine, tetracaine (dicaine), benzocaine(anesthesin), articaine, mepivacaine, and bupivacaine. Comparative data revealed certain disadvantages for each drug.Procaine (novocaine) is prone to causing allergic reactions, while lidocaine is characterized by a relatively short durationof action. The high toxicity of tetracaine (dicaine) makes it unsuitable for conduction, infiltration, and epidural anesthesia.Benzocaine (anesthesin), due to its low water solubility, is not suitable for parenteral administration. Articaine stands outamong local anesthetics due to its high potency-to-toxicity ratio, which accounts for its priority use in clinical practice asa local anesthetic.

Maqola ma’lumotlari
MualliflarMakhmudovna, Zulfiya, Buzrukzoda , Javohir
JurnalМактабгача ва мактаб таълими
NashriyotТошкент давлат педагогика университети
ISSN3060-4613, 3060-4613
Nashr sanasi2026-02-02
Jild4
Son2
TilIngliz
DOI10.5281/zenodo.18657357
Indeksga qo‘shilgan2026-08-27

DOI: 10.5281/zenodo.18657357 · Maqolaning asl sahifasi

Kalit so‘zlar

surgical operation, analgesia, local anesthetic drugs

Iqtibos keltirish

APAMakhmudovna, Zulfiya, & Buzrukzoda , Javohir (2026). Local Anesthesia and Conduction Anesthesia. Мактабгача ва мактаб таълими, 4(2). https://doi.org/10.5281/zenodo.18657357
GOST (OAK)Makhmudovna, Zulfiya, Buzrukzoda , Javohir Local Anesthesia and Conduction Anesthesia // Мактабгача ва мактаб таълими. – 2026. – T. 4, № 2. – DOI: 10.5281/zenodo.18657357.
MLAMakhmudovna, Zulfiya, and Buzrukzoda , Javohir. “Local Anesthesia and Conduction Anesthesia.” Мактабгача ва мактаб таълими, 4(2), 2026. https://doi.org/10.5281/zenodo.18657357
ChicagoMakhmudovna, Zulfiya, and Buzrukzoda , Javohir. “Local Anesthesia and Conduction Anesthesia.” Мактабгача ва мактаб таълими, 4(2) (2026). https://doi.org/10.5281/zenodo.18657357
HarvardMakhmudovna, Zulfiya, and Buzrukzoda , Javohir (2026) ‘Local Anesthesia and Conduction Anesthesia’, Мактабгача ва мактаб таълими, 4(2). https://doi.org/10.5281/zenodo.18657357
BibTeX
@article{makhmudovnazulfiya2026,
  title = {Local Anesthesia and Conduction Anesthesia},
  author = {Makhmudovna, Zulfiya and Buzrukzoda , Javohir},
  journal = {Мактабгача ва мактаб таълими},
  year = {2026},
  volume = {4},
  number = {2},
  doi = {10.5281/zenodo.18657357},
  url = {https://doi.org/10.5281/zenodo.18657357}
}

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