Purpose: Study of the functional state of the reproductive system in patients with inactive pituitary adenoma (IPA). Materials and methods: Data of 325 patients (145 women and 180 men) aged 18 to 70 years with IPA were analyzed, the diagnosis of which is confirmed by clinical, hormonal and imaging examinations. Results: In the analysis of the state of the sexual system in 33 women with IPA up to the age of 50 , the following groups were identified: 1) patients with oligomenorrhea; 2) patients with secondary amenorrhea; 3) patients with preserved menstrual cycle and no changes in pelvic organs in ultrasound. The state of the sexual system in men, depending on clinical and hormonal features, was characterized primarily by fading libido. A decrease in libido occurred in patients with normal testosterone (T) in blood serum, and at its concentration above 5 nmol/l. All patients with sexual dysfunction had elevated levels of PRL, which, together with reduced T, likely resulted in sexual dysfunction in men. Conclusion: Among patients with IPA, 90.2% of all patients of reproductive age suffer from sexual disorders, and the larger the tumor size, the higher the disorder rate. There is a high rate of infertility in both women and men suffering from IPA, which amounted to 69.8 and 53.3% of cases, respectively. The level of gonadotropins may change either upwards or downwards, or may remain within normal values.
| Mualliflar | Холова Д.Ш, Халимова З.Ю |
|---|---|
| Jurnal | Марказий Осиё эндокринологик журнали |
| Nashriyot | Республика ихтисослаштирилган эндокринология илмий-амалий тиббиёт маркази |
| ISSN | 2181-3426 |
| Nashr sanasi | 2022-08-29 |
| Jild | 2 |
| Son | 1 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-09-07 |
неактивная аденома гипофиза, репродуктивная система, репродуктивные нарушения, гипофиз нофаол аденомаси, репродуктив тизим, репродуктив етишмовчилик, inactive pituitary adenoma, reproductive system, reproductive disorders
| APA | Холова Д.Ш, & Халимова З.Ю (2022). STUDY OF REPRODUCTIVE SYSTEM FUNCTION OF PATIENTS WITH INACTIVE PITUITARY ADENOMA. Марказий Осиё эндокринологик журнали, 2(1). https://www.tadqiqot.uz/index.php/cae/article/view/5338 |
|---|---|
| GOST (OAK) | Холова Д.Ш, Халимова З.Ю STUDY OF REPRODUCTIVE SYSTEM FUNCTION OF PATIENTS WITH INACTIVE PITUITARY ADENOMA // Марказий Осиё эндокринологик журнали. – 2022. – T. 2, № 1. |
| MLA | Холова Д.Ш, and Халимова З.Ю. “STUDY OF REPRODUCTIVE SYSTEM FUNCTION OF PATIENTS WITH INACTIVE PITUITARY ADENOMA.” Марказий Осиё эндокринологик журнали, 2(1), 2022. https://www.tadqiqot.uz/index.php/cae/article/view/5338 |
| Chicago | Холова Д.Ш, and Халимова З.Ю. “STUDY OF REPRODUCTIVE SYSTEM FUNCTION OF PATIENTS WITH INACTIVE PITUITARY ADENOMA.” Марказий Осиё эндокринологик журнали, 2(1) (2022). https://www.tadqiqot.uz/index.php/cae/article/view/5338 |
| Harvard | Холова Д.Ш, and Халимова З.Ю (2022) ‘STUDY OF REPRODUCTIVE SYSTEM FUNCTION OF PATIENTS WITH INACTIVE PITUITARY ADENOMA’, Марказий Осиё эндокринологик журнали, 2(1). https://www.tadqiqot.uz/index.php/cae/article/view/5338 |
| BibTeX | @article{article2022,
title = {STUDY OF REPRODUCTIVE SYSTEM FUNCTION OF PATIENTS WITH INACTIVE PITUITARY ADENOMA},
author = {Холова Д.Ш and Халимова З.Ю},
journal = {Марказий Осиё эндокринологик журнали},
year = {2022},
volume = {2},
number = {1},
url = {https://www.tadqiqot.uz/index.php/cae/article/view/5338}
} |
Boshqa maqola uchun iqtibos tayyorlash
Актуальность. На сегодняшний день избыточной массой тела и ожирением страдают более 1,6 миллиарда человек, около трети из них ожирением и их число неуклонно увеличивается. Ожирение считается новой «глобальной…
Background. Hypergonadotropic hypogonadism with the primary insufficiency of the gonad, leading to an increase in the level of gonadotropin due to the lack of negative feedback approximately 7% of male patients and in…
Diffuse toxic goiter (Graves' disease) and autoimmune thyroiditis (Hoshimoto's goiter) as the main autoimmune thyropathies, require a number of immunodiagnostic studies. It is well known that the pathogenesis and…
WHO defines iodine deficiency diseases (IDD) as a spectrum of pathological disorders that can be prevented by normalizing iodine intake. The main reason for iodine deficiency is that a person usually does not receive…
Accordingly, as GFR decreases, substrate delivery is limited, which may compromise the ability of the affected kidney to produce 1,25-dihydroxyvitamin D. This may be exacerbated by a decrease in 25-hydroxyvitamin D…
The problem of obesity and fertility disorders is an important part of reproductive endocrinology. Infertility in obesity is considered through the hypothalamus-pituitary-gonads axis and metabolic disorders. At the same…
Differential diagnosis of benign and malignant tumors of the adrenal glands presents certain difficulties, since there is no specific histological criterion to differentiate tumors of the adrenal cortex with a malignant…
Introduction. When selecting hypoglycemic therapy, it is necessary to take into account not only the effectiveness of the drug, but also its effect on risk factors for the development of cardiovascular complications, in…
Введение: сочетание ожирения, инсулинорезистентности и гипергликемии при сахарном диабете 2 типа ускоряет развитие и прогрессирование атеросклероза, а также повышает риск развития сердечно-сосудистых осложнений. Цель…
В настоящее время тиреоидологическими ассоциациями не приняты единые клинические гайдлайны лечения болезни Грейвса (БГ) у детей и подростков. Остается много вопросов по выбору тактики лечения, длительности…
Марказий Осиё эндокринологик журнали — barcha maqolalar · 2022-yil arxivi
In this article, we consider the features of the clinical course of hypogonadotropic hypogondism, its etiology and pathogenesis in women of reproductive age with inactive pituitary adenoma. According to the literature…
Postmenopauzal osteoporoz suyak mineral zichligining pasayishi va suyak mikroarxitekturasining buzilishi bilan tavsiflanuvchi metabolik kasallik bo’lib, sinishlar xavfining ortishi bilan kechadi. So’nggi yillarda…
The article is devoted to the basic molecular-genetic mechanisms and novel approaches to the diagnosis and management of the development of central precocious puberty. Precocious puberty is the appearance of the…
This study was conducted to investigate etiological factors, incidence of different forms, as well as clinical and hormonal characteristics of Uzbek children with Precocious Puberty from 2016 to 2023. Materials and…
Target. Early diagnosis of inactive pituitary adenoma (IPA) is an urgent problem not only in modern health care, including neuroendocrinology, but also a medical and social problem. Aggressive pituitary adenomas, which…
Qalqonsimon bez tugunlari endokrin tizim kasalliklari orasida keng tarqalgan patologik holatlardan biri bo‘lib, zamonaviy ultratovush tekshiruvlari yordamida kattalar aholisining 40–60 % ida aniqlanadi. Tugunlarning…
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…