Precocious puberty: molecular genetics, modern approaches to the diagnosis and treatment

Халимова З.Ю., Уралова Д.У., Абдуллаева А.У., Холова Д.Ш., Рахимова Г.Н., Сулейманова Ф.Н.

Марказий Осиё эндокринологик журнали · 2023-yil

Annotatsiya

The article is devoted to the basic molecular-genetic mechanisms and novel approaches to the diagnosis and management of the development of central precocious puberty. Precocious puberty is the appearance of the secondary sexual characteristics before the age years in girls and before 9 years in boys. Prevalence varies greatly by study. The incidence is generally thought to be 1 in 5000-10000 children, but some countries around the world have seen an increase in the incidence, including the United States, Spain, France, Denmark, Korea and China since 1990. Complex interactions with genetic, nutritional and environmental factors play a decisive role in determining the timing of puberty. To date, mutations in four genes (KISS1, KISS1R, MKRN3, DLK1) have been confirmed as causal variants leading to central idiopathic Precocious Puberty.

Maqola ma’lumotlari
MualliflarХалимова З.Ю., Уралова Д.У., Абдуллаева А.У., Холова Д.Ш., Рахимова Г.Н., Сулейманова Ф.Н.
JurnalМарказий Осиё эндокринологик журнали
NashriyotРеспублика ихтисослаштирилган эндокринология илмий-амалий тиббиёт маркази
ISSN2181-3426
Nashr sanasi2023-09-03
Jild3
Son2
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-10

Maqolaning asl sahifasi

Kalit so‘zlar

преждевременное половое созревание, центральное преждевременное половое развитие (ЦППР), периферическое преждевременное половое развитие (ПППР), идиопатическое, KISS1, KISS1R, MKRN3, DLK1, врожденная дисфункция коры надпочечников, синдром Мак-Кьюна-Олбрайта, precocious puberty (PP), central precocious puberty (CPP), peripheral precocious puberty (PPP), idiopathic, KISS1, KISS1R, MKRN3, DLK1, congenital adrenal hyperplasia, Mc- Cune Albright syndrome, erta jinsiy yetilish (EJY), markaziy erta jinsiy yetilish (MEJY), periferik erta jinsiy yetilish (PEJY),idiopatik, KISS1, KISS1R, MKRN3, DLK1, buyrakusti bezi po’stlog’i

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAХалимова З.Ю., Уралова Д.У., Абдуллаева А.У., Холова Д.Ш., Рахимова Г.Н., & Сулейманова Ф.Н. (2023). PRECOCIOUS PUBERTY: MOLECULAR GENETICS, MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT. Марказий Осиё эндокринологик журнали, 3(2). https://www.tadqiqot.uz/index.php/cae/article/view/7835
GOST (OAK)Халимова З.Ю. va b. PRECOCIOUS PUBERTY: MOLECULAR GENETICS, MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT // Марказий Осиё эндокринологик журнали. – 2023. – T. 3, № 2.
MLAХалимова З.Ю., Уралова Д.У., Абдуллаева А.У., Холова Д.Ш., Рахимова Г.Н., and Сулейманова Ф.Н. “PRECOCIOUS PUBERTY: MOLECULAR GENETICS, MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT.” Марказий Осиё эндокринологик журнали, 3(2), 2023. https://www.tadqiqot.uz/index.php/cae/article/view/7835
ChicagoХалимова З.Ю., Уралова Д.У., Абдуллаева А.У., Холова Д.Ш., Рахимова Г.Н., and Сулейманова Ф.Н. “PRECOCIOUS PUBERTY: MOLECULAR GENETICS, MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT.” Марказий Осиё эндокринологик журнали, 3(2) (2023). https://www.tadqiqot.uz/index.php/cae/article/view/7835
HarvardХалимова З.Ю., Уралова Д.У., Абдуллаева А.У., Холова Д.Ш., Рахимова Г.Н., and Сулейманова Ф.Н (2023) ‘PRECOCIOUS PUBERTY: MOLECULAR GENETICS, MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT’, Марказий Осиё эндокринологик журнали, 3(2). https://www.tadqiqot.uz/index.php/cae/article/view/7835
BibTeX
@article{article2023,
  title = {PRECOCIOUS PUBERTY: MOLECULAR GENETICS, MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT},
  author = {Халимова З.Ю. and Уралова Д.У. and Абдуллаева А.У. and Холова Д.Ш. and Рахимова Г.Н. and Сулейманова Ф.Н.},
  journal = {Марказий Осиё эндокринологик журнали},
  year = {2023},
  volume = {3},
  number = {2},
  url = {https://www.tadqiqot.uz/index.php/cae/article/view/7835}
}

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