According to international standards for the management and treatment of patients with type 2 diabetes mellitus, patients with a reduced glomerular filtration rate (GFR) below 60 ml / min / 1.73 m2, albuminuria, or both in the last 3 months, are diagnosed with chronic kidney disease (CKD) [11]. Chronic kidney disease in type 2 diabetes is not only dangerous for the development of end-stage complications of the kidneys, such as dialysis or transplantation, but also causes a high mortality rate from cardiovascular complications compared with patients without chronic kidney disease and type 2 diabetes [7]. The goal of modern diabetology is to reduce albuminuria and prevent the progression of a decrease in GFR.In our article, we will review and summarize information on the safety and efficacy of using a combination of an SGLT-2 inhibitor and an agonist of GLP-1 receptors, as well as the introduction of this combination into the clinical practice of an endocrinologist in the management of patients with diabetes mellitus and chronic kidney disease.
| Mualliflar | Рахимова Г.Н, Ахроров К.У |
|---|---|
| Jurnal | Марказий Осиё эндокринологик журнали |
| Nashr sanasi | 2022-08-26 |
| Jild | 2 |
| Son | 1 |
| Til | Rus |
Агонисты рецептора ГПП-1; ингибиторы НГКТ-2; инфаркт; скорость клубочковой фильтрации; смертность; сахарный диабет 2 типа; хроническая болезнь почек, GO’P-1 retseptorlari agonistlari; NGKT-2 ingibitorlari; yurak xuruji; koptokchalar filtratsiya tezligi; o'lim darajasi; 2-tur qandli diabet; surunkali buyrak kasalligi, GLP-1 receptor agonists; SGLT-2 inhibitors; heart attack; glomerular filtration rate; mortality; type 2 diabetes mellitus; chronic kidney disease
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