Comparison of the clinical and radiological efficacy of epoxy silers of traditional composition and with additives of quaternary ammonium

SULEYMENOV Askar Nurlanovich, ALIMOVA Dono Mirdjamalovna, ESHIMOVA Parvina Bekhzod qizi

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

The success of endodontic treatment largely depends on thorough sanitation and hermetic obturation of the root canal system; however, the persistence of Enterococcus faecalis often leads to chronic apical periodontitis and relapses. Epoxy sealers provide favorable physico-chemical properties, but their antimicrobial activity is limited; the incorporation of quaternary ammonium compounds enhances the antibacterial potential of the material, which determined the relevance of this study. Objective: to compare the clinical and radiological efficacy of traditional epoxy sealers and sealers with quaternary ammonium additives in the treatment of chronic apical periodontitis. Materials and methods: the study included 20 patients divided into 2 groups (control, n=10 — traditional sealer; main, n=10 — modified sealer). Standard endodontic treatment with lateral condensation obturation was performed; clinical evaluation was carried out at 1, 3, 6, and 12 months, and radiological evaluation at 12 months; statistical analysis was performed using the χ² test (p<0.05). Results: symptoms in the main group occurred less frequently and resolved faster; after 12 months, complete healing was observed in 80% of patients compared to 50% in the control group (χ²=4.00; p=0.045). Conclusions: the use of epoxy sealer with quaternary ammonium compounds provides superior clinical and radiological outcomes compared to the traditional sealer, which is associated with its pronounced antimicrobial activity; however, further studies with larger samples and longer follow-up are required.

Maqola ma’lumotlari
MualliflarSULEYMENOV Askar Nurlanovich, ALIMOVA Dono Mirdjamalovna, ESHIMOVA Parvina Bekhzod qizi
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-11-21
Jild10
Son5
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

эндодонтическое лечение, хронический апикальный периодонтит, эпоксидный силер, четвертичные аммониевые соединения, антимикробная активность, клиническая эффективность, рентгенологическое заживление, модифицированные силеры, обтурация корневых каналов, endodontic treatment, chronic apical periodontitis, epoxy siler, quaternary ammonium compounds, antimicrobial activity, clinical efficacy, X-ray healing, modified silers, root canal obturation, endodontik davolash, surunkali apikal periodontit, epoksid asosli silerlar, to‘rtlamchi ammoniy birikmalari, mikroblarga qarshi faollik, klinik samaradorlik, rentgenologik tiklanish, modifikatsiyalangan silerlar, ildiz kanallari obturatsiyasi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APASULEYMENOV Askar Nurlanovich, ALIMOVA Dono Mirdjamalovna, & ESHIMOVA Parvina Bekhzod qizi (2025). COMPARISON OF THE CLINICAL AND RADIOLOGICAL EFFICACY OF EPOXY SILERS OF TRADITIONAL COMPOSITION AND WITH ADDITIVES OF QUATERNARY AMMONIUM. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5). https://tadqiqot.uz/index.php/biomedicine/article/view/12943
GOST (OAK)SULEYMENOV Askar Nurlanovich, ALIMOVA Dono Mirdjamalovna, ESHIMOVA Parvina Bekhzod qizi COMPARISON OF THE CLINICAL AND RADIOLOGICAL EFFICACY OF EPOXY SILERS OF TRADITIONAL COMPOSITION AND WITH ADDITIVES OF QUATERNARY AMMONIUM // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 5.
MLASULEYMENOV Askar Nurlanovich, ALIMOVA Dono Mirdjamalovna, and ESHIMOVA Parvina Bekhzod qizi. “COMPARISON OF THE CLINICAL AND RADIOLOGICAL EFFICACY OF EPOXY SILERS OF TRADITIONAL COMPOSITION AND WITH ADDITIVES OF QUATERNARY AMMONIUM.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/12943
ChicagoSULEYMENOV Askar Nurlanovich, ALIMOVA Dono Mirdjamalovna, and ESHIMOVA Parvina Bekhzod qizi. “COMPARISON OF THE CLINICAL AND RADIOLOGICAL EFFICACY OF EPOXY SILERS OF TRADITIONAL COMPOSITION AND WITH ADDITIVES OF QUATERNARY AMMONIUM.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/12943
HarvardSULEYMENOV Askar Nurlanovich, ALIMOVA Dono Mirdjamalovna, and ESHIMOVA Parvina Bekhzod qizi (2025) ‘COMPARISON OF THE CLINICAL AND RADIOLOGICAL EFFICACY OF EPOXY SILERS OF TRADITIONAL COMPOSITION AND WITH ADDITIVES OF QUATERNARY AMMONIUM’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5). https://tadqiqot.uz/index.php/biomedicine/article/view/12943
BibTeX
@article{suleymenovaskarnurlanovich2025,
  title = {COMPARISON OF THE CLINICAL AND RADIOLOGICAL EFFICACY OF EPOXY SILERS OF TRADITIONAL COMPOSITION AND WITH ADDITIVES OF QUATERNARY AMMONIUM},
  author = {SULEYMENOV Askar Nurlanovich and ALIMOVA Dono Mirdjamalovna and ESHIMOVA Parvina Bekhzod qizi},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {5},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/12943}
}

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