Laryngeal papillomatosis: a review of modern methods of diagnosis and treatment

AMONOV Shavkat Ergashevich, BEZBAKH Dmitry Ilyich, AMONOV Aminjon Shavkatovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Laryngeal papillomatosis is caused by HPV infection, primarily types 6 and 11, which are also responsible for the development of genital warts. HPV can be transmitted through various routes, including vertical and perinatal contact, which explains the development of LP in children. Clinically, the disease presents with hoarseness, stridor, cough, and, in severe cases, respiratory failure. The juvenile form, detected primarily in children under 5 years of age, has a more aggressive course and requires frequent surgical interventions. The primary cause of the disease is HPV types 6 and 11. The virus infects the respiratory epithelium, causing cell proliferation and papilloma formation. Viral proteins E6 and E7 disrupt cell cycle regulation, promoting the development of benign tumors. The body's immune response plays a key role in controlling infection, and impaired immune regulation is associated with frequent relapses and disease progression. The diagnosis is established by laryngoscopy with visualization of papillomatous growths, histological examination of biopsy material, and molecular diagnostics (PCR) to determine HPV types.

Maqola ma’lumotlari
MualliflarAMONOV Shavkat Ergashevich, BEZBAKH Dmitry Ilyich, AMONOV Aminjon Shavkatovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-11-20
Jild10
Son5
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

Ларингеальный папилломатоз, вирус папилломы человека (ВПЧ), лезерохирургия, Laryngeal papillomatosis, human papillomavirus (HPV), lesional surgery, Laringeal papillomatoz, inson papillomavirusi (IPV), lezerli jarrohlik

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAMONOV Shavkat Ergashevich, BEZBAKH Dmitry Ilyich, & AMONOV Aminjon Shavkatovich (2025). LARYNGEAL PAPILLOMATOSIS: A REVIEW OF MODERN METHODS OF DIAGNOSIS AND TREATMENT. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5). https://tadqiqot.uz/index.php/biomedicine/article/view/12939
GOST (OAK)AMONOV Shavkat Ergashevich, BEZBAKH Dmitry Ilyich, AMONOV Aminjon Shavkatovich LARYNGEAL PAPILLOMATOSIS: A REVIEW OF MODERN METHODS OF DIAGNOSIS AND TREATMENT // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 5.
MLAAMONOV Shavkat Ergashevich, BEZBAKH Dmitry Ilyich, and AMONOV Aminjon Shavkatovich. “LARYNGEAL PAPILLOMATOSIS: A REVIEW OF MODERN METHODS OF DIAGNOSIS AND TREATMENT.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/12939
ChicagoAMONOV Shavkat Ergashevich, BEZBAKH Dmitry Ilyich, and AMONOV Aminjon Shavkatovich. “LARYNGEAL PAPILLOMATOSIS: A REVIEW OF MODERN METHODS OF DIAGNOSIS AND TREATMENT.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/12939
HarvardAMONOV Shavkat Ergashevich, BEZBAKH Dmitry Ilyich, and AMONOV Aminjon Shavkatovich (2025) ‘LARYNGEAL PAPILLOMATOSIS: A REVIEW OF MODERN METHODS OF DIAGNOSIS AND TREATMENT’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5). https://tadqiqot.uz/index.php/biomedicine/article/view/12939
BibTeX
@article{amonovshavkatergashevich2025,
  title = {LARYNGEAL PAPILLOMATOSIS: A REVIEW OF MODERN METHODS OF DIAGNOSIS AND TREATMENT},
  author = {AMONOV Shavkat Ergashevich and BEZBAKH Dmitry Ilyich and AMONOV Aminjon Shavkatovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {5},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/12939}
}

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