This study addresses the significance of vascular endothelial growth factor A (VEGF-A) as a potential biomarker of endothelial dysfunction in individuals with severe manifestations of COVID-19, particularly those with pre-existing chronic comorbidities such as diabetes mellitus, hypertension, obesity, and cardiovascular diseases. Endothelial dysfunction has emerged as a key pathological feature in severe SARS-CoV-2 infection, contributing to a range of complications including microthrombosis, exaggerated vascular permeability, and systemic inflammatory responses.The assessment of circulating VEGF-A levels in COVID-19 patients may serve as an early indicator of disease severity and endothelial injury, offering potential utility in risk stratification, prognosis, and therapeutic decision-making. Moreover, VEGF-A could be explored as a target for adjunctive therapy, aiming to mitigate endothelial dysfunction and its clinical consequences in high-risk patient populations.
| Mualliflar | SAMIBAEVA Umida Khurshidovna |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashriyot | Тошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ |
| ISSN | 2181-9300 |
| Nashr sanasi | 2025-09-06 |
| Jild | 10 |
| Son | 3/2 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-27 |
Covid 19, коморбидность, фактор роста эндотелия сосудов (VEGF A), эндотелиальная дисфункция, Covid 19, comorbidity, vascular endothelial growth factor (VEGF A), endothelial dysfunction.
| APA | SAMIBAEVA Umida Khurshidovna (2025). VASCULAR ENDOTHELIAL GROWTH FACTOR VEGF-A AS A MARKER OF ENDOTHELIAL DYSFUNCTION ASSOCIATED WITH SEVERE COVID-19 IN PATIENTS WITH CHRONIC CONCOMITANT PATHOLOGY. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(3/2). https://tadqiqot.uz/index.php/biomedicine/article/view/12264 |
|---|---|
| GOST (OAK) | SAMIBAEVA Umida Khurshidovna VASCULAR ENDOTHELIAL GROWTH FACTOR VEGF-A AS A MARKER OF ENDOTHELIAL DYSFUNCTION ASSOCIATED WITH SEVERE COVID-19 IN PATIENTS WITH CHRONIC CONCOMITANT PATHOLOGY // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 3/2. |
| MLA | SAMIBAEVA Umida Khurshidovna. “VASCULAR ENDOTHELIAL GROWTH FACTOR VEGF-A AS A MARKER OF ENDOTHELIAL DYSFUNCTION ASSOCIATED WITH SEVERE COVID-19 IN PATIENTS WITH CHRONIC CONCOMITANT PATHOLOGY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(3/2), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/12264 |
| Chicago | SAMIBAEVA Umida Khurshidovna. “VASCULAR ENDOTHELIAL GROWTH FACTOR VEGF-A AS A MARKER OF ENDOTHELIAL DYSFUNCTION ASSOCIATED WITH SEVERE COVID-19 IN PATIENTS WITH CHRONIC CONCOMITANT PATHOLOGY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(3/2) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/12264 |
| Harvard | SAMIBAEVA Umida Khurshidovna (2025) ‘VASCULAR ENDOTHELIAL GROWTH FACTOR VEGF-A AS A MARKER OF ENDOTHELIAL DYSFUNCTION ASSOCIATED WITH SEVERE COVID-19 IN PATIENTS WITH CHRONIC CONCOMITANT PATHOLOGY’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(3/2). https://tadqiqot.uz/index.php/biomedicine/article/view/12264 |
| BibTeX | @article{samibaevaumidakhurshidovna2025,
title = {VASCULAR ENDOTHELIAL GROWTH FACTOR VEGF-A AS A MARKER OF ENDOTHELIAL DYSFUNCTION ASSOCIATED WITH SEVERE COVID-19 IN PATIENTS WITH CHRONIC CONCOMITANT PATHOLOGY},
author = {SAMIBAEVA Umida Khurshidovna},
journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
year = {2025},
volume = {10},
number = {3/2},
url = {https://tadqiqot.uz/index.php/biomedicine/article/view/12264}
} |
Boshqa maqola uchun iqtibos tayyorlash
Energy drinks (EI) are soft drinks that contain high amounts of caffeine and some psychoactive substances, including the amino acid taurine, glucuronolactone and plant extracts - ginseng, guarana, B vitamins. Energy…
According to the histochemical studies used in the study, no changes were observed in the number of goblet cells in the intestines during the study, but their number was higher in the distal section than in the proximal…
Immunohistochemical studies play a crucial role in diagnosing and developing treatment strategies for salivary gland tumors. This method allows for the determination of the morphological and molecular characteristics of…
Metabolic syndrome (MS) significantly affects the morphofunctional state of the small intestine, leading to pronounced histological and ultrastructural alterations. This study explores key pathological processes…
In the studies deeply revealed pathogenesis of disorders occurring in the body of animals under the influence of a complex of physical factors: complex biochemical processes, which reflect the measures that prevent the…
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that can manifest with various neurological disorders. Young patients often present with acute attacks such as visual disturbances…
Microcurrent reflexology for microcephaly, as for other diseases, has not proven its effectiveness as a primary treatment method. As a result of scientific research conducted in recent years, this problem, like many…
87 patients with cerebrovascular diseases and strokes aged 50 to 78 years were examined, the average age was 67.9 ± 4.8 years. In patients with cerebrovascular diseases, a tendency was revealed to increase the level of…
The article reveals the problem of dorsopathy in military personnel, the study of which showed that this is a common problem and it can negatively affect their physical readiness and ability to perform official…
Discs are a type of cushion between the vertebrae in the spine. The spine consists of twenty-four movable vertebrae and five fused vertebrae that form the sacrum. Discs are susceptible to injury because, on the one…
Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar · 2025-yil arxivi
The purpose of this study is to compare the nature of the clinical course of measles in children under one year of age who were breastfed with those who were bottle-fed. The clinical diagnosis of measles was established…
A review of the literature data shows that the main complication in patients with COVID-19, which determines the severity of the disease and fatal outcomes, remains pneumonia in all countries of the world, the etiology…
Bacterial complications of COVID-19 are very common and directly impact the severity and outcome of the disease. This study identified a spectrum of clinically significant bacterial pathogens in samples collected from…
A prospective study of 163 patients with the new coronavirus infection COVID-19, hospitalized in the Samarkand Regional Specialized Medical Center for the period 2020-2022, was conducted. The level of vascular…
An analysis of clinical and laboratory data was conducted on 210 patients with moderate and severe forms of COVID-19 hospitalized in the clinic of the Samarkand Regional Specialized Medical Center in the period…
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has created a serious threat to public health. Today, the development of medicine in our country requires the adaptation of the medical system to the requirements…
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…