This study addresses the significance of vascular endothelial growth factor A (VEGF-A) as a potential biomarker of endothelial dysfunction in individuals with severe manifestations of COVID-19, particularly those with pre-existing chronic comorbidities such as diabetes mellitus, hypertension, obesity, and cardiovascular diseases. Endothelial dysfunction has emerged as a key pathological feature in severe SARS-CoV-2 infection, contributing to a range of complications including microthrombosis, exaggerated vascular permeability, and systemic inflammatory responses.The assessment of circulating VEGF-A levels in COVID-19 patients may serve as an early indicator of disease severity and endothelial injury, offering potential utility in risk stratification, prognosis, and therapeutic decision-making. Moreover, VEGF-A could be explored as a target for adjunctive therapy, aiming to mitigate endothelial dysfunction and its clinical consequences in high-risk patient populations.
| Mualliflar | SAMIBAEVA Umida Khurshidovna |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2025-09-06 |
| Jild | 10 |
| Son | 3/2 |
| Til | Ingliz |
Covid 19, коморбидность, фактор роста эндотелия сосудов (VEGF A), эндотелиальная дисфункция, Covid 19, comorbidity, vascular endothelial growth factor (VEGF A), endothelial dysfunction.
In this article, an analysis of data obtained from macroscopic and microscopic studies of the thyroid gland in 5-month-old mongrel rats is presented, as well as an analysis of the similarities and differences between…
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Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that can manifest with various neurological disorders. Young patients often present with acute attacks such as visual disturbances…
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Microcurrent reflexology for microcephaly, as for other diseases, has not proven its effectiveness as a primary treatment method. As a result of scientific research conducted in recent years, this problem, like many…
Immunohistochemical studies play a crucial role in diagnosing and developing treatment strategies for salivary gland tumors. This method allows for the determination of the morphological and molecular characteristics of…
87 patients with cerebrovascular diseases and strokes aged 50 to 78 years were examined, the average age was 67.9 ± 4.8 years. In patients with cerebrovascular diseases, a tendency was revealed to increase the level of…
According to the histochemical studies used in the study, no changes were observed in the number of goblet cells in the intestines during the study, but their number was higher in the distal section than in the proximal…
The article reveals the problem of dorsopathy in military personnel, the study of which showed that this is a common problem and it can negatively affect their physical readiness and ability to perform official…
Energy drinks (EI) are soft drinks that contain high amounts of caffeine and some psychoactive substances, including the amino acid taurine, glucuronolactone and plant extracts - ginseng, guarana, B vitamins. Energy…
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