A prospective study of 163 patients with the new coronavirus infection COVID-19, hospitalized in the Samarkand Regional Specialized Medical Center for the period 2020-2022, was conducted. The level of vascular endothelial growth factor (VEGF A) in the blood serum was studied using the enzyme-linked immunosorbent assay method. The results of the conducted studies on the pathogenetic significance of markers of endothelial dysfunction in COVID-19 associated pneumonia showed that the endothelial dysfunction marker VEGF-A reaches reliably high levels, having a strong correlation with inflammatory markers both during admission to hospital, as well as during the discharge period. In this regard, pathogenetic therapy, including drugs with anti-inflammatory, antioxidant, and antifibrogenic effects during the early recovery period of COVID-19, is highly advisable.
| Mualliflar | FAYZULLAYEV Sherzod Qobiljon o'g'li, SHAKHAROV Dilshod Zhura ugli, TUKHTAEV Shohzod Eshmurod ugli, KHUZHAMBERDIEV Sodikjon Uchkun ugli, SAMIBAEVA Umida Khurshidovna |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2026-04-26 |
| Jild | 11 |
| Son | 1 |
| Til | Rus |
Covid 19 ассоциированная пневмония, глициризиновая кислота, фактор роста эндотелия сосудов (VEGF A), эндотелиальная дисфункция, Covid 19 associated pneumonia, glycyrrhizic acid, vascular endothelial growth factor (VEGF A), endothelial dysfunction, Covid 19 bilan bog'liq pnevmoniya, glitsirizin kislotasi, qon tomir endotelial o'sish omili (VEGF A), endotelial disfunktsiya
The study of 50 patients with various forms of renal tuberculosis was conducted using gray-scale echography, triplex, color, and energy dopplerography. The results showed that changes in renal blood flow are directly…
An analysis of clinical and laboratory data was conducted on 210 patients with moderate and severe forms of COVID-19 hospitalized in the clinic of the Samarkand Regional Specialized Medical Center in the period…
The article examines the main types of surgical treatment of cataracts in children, including lens extraction, phacoaspiration, and phacoemulsification, with or without intraocular lens implantation, depending on the…
This article analyzes the impact of physical exercise and dietary factors on the composition and bacterial diversity of the gut microflora. Regular physical activity promotes an increase in beneficial bacteria in the…
The article presents an analysis of two clinical cases of late postoperative complications following congenital cataract extraction in children, accompanied by intraocular lens (IOL) subluxation and iris involvement…
Purpose of the study: To study the modern etiological spectrum and structure of dermatomycosis pathogens in the Tashkent region based on cultural studies, to determine the dynamics of changes in the species composition…
Introduction. Refractive disorders are common among preschool children and are often underdiagnosed during routine screening. Engaging parents in the screening process can improve early identification of risk factors…
Purpose of the study:The temperature range for the cultivation of pathogenic fungal pathogens in a nutrient medium based on local ingredients was studied. Materials and methods of research: In the course of scientific…
Background. Chronic migraine with pain localized in the occipital region is often associated with compression of the greater occipital nerve within its myofascial segment and is frequently resistant to conservative…
Breast hypertrophy is characterized by an increase in tissue volume without underlying pathology and often requires reduction mammaplasty. Surgical safety depends on preserving the blood supply to the nipple-areola…
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