Comparison of allele and genotype frequencies of the umod gene polymorphism RS4293393 between patients with chronic glomerulonephritis and a control group

TOSHKENBAYEVA Eleonora Negmatovna, ESANKULOV Mukhammad Olimovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

This study focuses on the comparative analysis of allele and genotype frequencies of the UMOD gene polymorphic marker rs4293393 in patients with chronic glomerulonephritis (CGN) and a control group. The aim is to identify potential associations between allelic variants and the risk of CGN. Data collection and analysis revealed the distribution of alleles C and T among patients and controls. Allele C was found more frequently in patients with CGN than in the control group (30.91% vs. 25.84%, OR = 1.28, 95% CI: 0.80–2.05), though statistical significance was not achieved (p = 0.356). Conversely, allele T was less frequent among patients (69.09% vs. 74.16%, OR = 0.78, 95% CI: 0.49–1.24), also without statistical significance (p = 0.356). The results suggest a weak association between the UMOD rs4293393 polymorphism and CGN risk, warranting further research for confirmation.

Maqola ma’lumotlari
MualliflarTOSHKENBAYEVA Eleonora Negmatovna, ESANKULOV Mukhammad Olimovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-03-29
Jild10
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-13

Maqolaning asl sahifasi

Kalit so‘zlar

ген UMOD, rs4293393, хронический гломерулонефрит, частота аллелей, распределение генотипов, полиморфизм, генетическая ассоциация, оценка риска, UMOD gene, rs4293393, chronic glomerulonephritis, allele frequency, genotype distribution, polymorphism, genetic association, risk assessment, UMOD geni, rs4293393, surunkali glomerulonefrit, allel chastotasi, genotip taqsimoti, polimorfizm, genetik bog‘liqlik, xavfni baholash

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APATOSHKENBAYEVA Eleonora Negmatovna, & ESANKULOV Mukhammad Olimovich (2025). COMPARISON OF ALLELE AND GENOTYPE FREQUENCIES OF THE UMOD GENE POLYMORPHISM RS4293393 BETWEEN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS AND A CONTROL GROUP. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1). https://tadqiqot.uz/index.php/biomedicine/article/view/11175
GOST (OAK)TOSHKENBAYEVA Eleonora Negmatovna, ESANKULOV Mukhammad Olimovich COMPARISON OF ALLELE AND GENOTYPE FREQUENCIES OF THE UMOD GENE POLYMORPHISM RS4293393 BETWEEN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS AND A CONTROL GROUP // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 1.
MLATOSHKENBAYEVA Eleonora Negmatovna, and ESANKULOV Mukhammad Olimovich. “COMPARISON OF ALLELE AND GENOTYPE FREQUENCIES OF THE UMOD GENE POLYMORPHISM RS4293393 BETWEEN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS AND A CONTROL GROUP.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/11175
ChicagoTOSHKENBAYEVA Eleonora Negmatovna, and ESANKULOV Mukhammad Olimovich. “COMPARISON OF ALLELE AND GENOTYPE FREQUENCIES OF THE UMOD GENE POLYMORPHISM RS4293393 BETWEEN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS AND A CONTROL GROUP.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/11175
HarvardTOSHKENBAYEVA Eleonora Negmatovna, and ESANKULOV Mukhammad Olimovich (2025) ‘COMPARISON OF ALLELE AND GENOTYPE FREQUENCIES OF THE UMOD GENE POLYMORPHISM RS4293393 BETWEEN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS AND A CONTROL GROUP’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1). https://tadqiqot.uz/index.php/biomedicine/article/view/11175
BibTeX
@article{toshkenbayevaeleonoranegmatovna2025,
  title = {COMPARISON OF ALLELE AND GENOTYPE FREQUENCIES OF THE UMOD GENE POLYMORPHISM RS4293393 BETWEEN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS AND A CONTROL GROUP},
  author = {TOSHKENBAYEVA Eleonora Negmatovna and ESANKULOV Mukhammad Olimovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/11175}
}

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