To study the clinical efficacy and safety of direct-acting oral anticoagulants in patients with atrial fibrillation treated in a real clinical setting. In this study, 356 AF patients aged 50 to 75 years with a creatinine clearance rate of at least 50 ml/min were observed. Patients were divided into 3 groups according to the type of POAC taken: Group 1 (n=120) took rivaroxaban at a dose of 20 mg/1 g/day; Group 2 (n=112) took dabigatran etexilate at a dose of 150 g/day mg/1 g/day 2 times a day; and Group 3 (n=124) took apixaban at a dose of 5 mg/2 times a day. The groups of patients were compared by age, concomitant pathology, risk of thromboembolic and hemorrhagic complications. The study period was 2 years from the time of drug administration. The endpoints were thromboembolic complications, major bleeding events and death from any cause.
| Mualliflar | Исмаилов Джамшид Абдураимович, Хамраев Фарид Хамидуллаевич, Хамидуллаев Фирдавс Фаридович, Расули Фарида Орифовна, Тураев Хикматилла Негматович |
|---|---|
| Jurnal | Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali |
| Nashr sanasi | 2024-02-01 |
| Jild | 4 |
| Son | 4 |
| Til | Ingliz |
фибрилляция предсердий, пероральные антикоагулянты, тромбоэмболические осложнения, инфаркт, инсульт, atrial fibrillation, oral anticoagulants, thromboembolic complications, infarction, stroke, atriyal fibrilatsiya, og'iz antikoagulyantlari, tromboembolik asoratlar, yurak xuruji, qon tomir
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