Evaluation of the effect of epitriazoline on the general blood count, biochemical and macroscopic condition of the internal organs of experimental animals with prolonged administration

Zafar Sanoev, Tolmas Khamroev, Ibrohimjon Abdinazarov, Suhrob Rakhimboev, Sohib Rashidov, Dilnoza Ismailova, Burhon Elmuradov

Фармация ва фармакология · 2026-yil

Annotatsiya

Experimental studies have revealed that the compound 4-(6-phenyl-7H-[1,2,4] triazolo[3,4-b][1,3,4]thiadiazine-3-yl)-aniline, called epitriazoline, has high anticonvulsant activity when administered orally to experimental animals at doses of 0.25, 2.5 and 25 mg/kg per for 90 days, it does not adversely affect changes in body weight and the macroscopic condition of internal organs. It was revealed, based on a general blood test and biochemical parameters, that epitriazoline is not toxic and does not cause side effects, which indicates the possibility of using it in the future in medical practice in the treatment of epilepsy.

Maqola ma’lumotlari
MualliflarZafar Sanoev, Tolmas Khamroev, Ibrohimjon Abdinazarov, Suhrob Rakhimboev, Sohib Rashidov, Dilnoza Ismailova, Burhon Elmuradov
JurnalФармация ва фармакология
NashriyotФармацевтика ТТИ
ISSN2181-3159, 2016-2022
Nashr sanasi2026-04-20
Jild1
Son15
Betlar130-136
TilIngliz
Ilmiy sohaBiologiya
DOI10.66657/phcc/vol1_iss6-15/art18
Indeksga qo‘shilgan2026-09-02

DOI: 10.66657/phcc/vol1_iss6-15/art18 · Maqolaning asl sahifasi · PDF

Ilmiy soha

Biologiya

Iqtibos keltirish

APAZafar Sanoev, Tolmas Khamroev, Ibrohimjon Abdinazarov, Suhrob Rakhimboev, Sohib Rashidov, Dilnoza Ismailova, & Burhon Elmuradov (2026). EVALUATION OF THE EFFECT OF EPITRIAZOLINE ON THE GENERAL BLOOD COUNT, BIOCHEMICAL AND MACROSCOPIC CONDITION OF THE INTERNAL ORGANS OF EXPERIMENTAL ANIMALS WITH PROLONGED ADMINISTRATION. Фармация ва фармакология, 1(15), 130-136. https://doi.org/10.66657/phcc/vol1_iss6-15/art18
GOST (OAK)Zafar Sanoev va b. EVALUATION OF THE EFFECT OF EPITRIAZOLINE ON THE GENERAL BLOOD COUNT, BIOCHEMICAL AND MACROSCOPIC CONDITION OF THE INTERNAL ORGANS OF EXPERIMENTAL ANIMALS WITH PROLONGED ADMINISTRATION // Фармация ва фармакология. – 2026. – T. 1, № 15. – P. 130-136. – DOI: 10.66657/phcc/vol1_iss6-15/art18.
MLAZafar Sanoev, Tolmas Khamroev, Ibrohimjon Abdinazarov, Suhrob Rakhimboev, Sohib Rashidov, Dilnoza Ismailova, and Burhon Elmuradov. “EVALUATION OF THE EFFECT OF EPITRIAZOLINE ON THE GENERAL BLOOD COUNT, BIOCHEMICAL AND MACROSCOPIC CONDITION OF THE INTERNAL ORGANS OF EXPERIMENTAL ANIMALS WITH PROLONGED ADMINISTRATION.” Фармация ва фармакология, 1(15), 130-136, 2026. https://doi.org/10.66657/phcc/vol1_iss6-15/art18
ChicagoZafar Sanoev, Tolmas Khamroev, Ibrohimjon Abdinazarov, Suhrob Rakhimboev, Sohib Rashidov, Dilnoza Ismailova, and Burhon Elmuradov. “EVALUATION OF THE EFFECT OF EPITRIAZOLINE ON THE GENERAL BLOOD COUNT, BIOCHEMICAL AND MACROSCOPIC CONDITION OF THE INTERNAL ORGANS OF EXPERIMENTAL ANIMALS WITH PROLONGED ADMINISTRATION.” Фармация ва фармакология, 1(15), 130-136 (2026). https://doi.org/10.66657/phcc/vol1_iss6-15/art18
HarvardZafar Sanoev, Tolmas Khamroev, Ibrohimjon Abdinazarov, Suhrob Rakhimboev, Sohib Rashidov, Dilnoza Ismailova, and Burhon Elmuradov (2026) ‘EVALUATION OF THE EFFECT OF EPITRIAZOLINE ON THE GENERAL BLOOD COUNT, BIOCHEMICAL AND MACROSCOPIC CONDITION OF THE INTERNAL ORGANS OF EXPERIMENTAL ANIMALS WITH PROLONGED ADMINISTRATION’, Фармация ва фармакология, 1(15), 130-136. https://doi.org/10.66657/phcc/vol1_iss6-15/art18
BibTeX
@article{zafarsanoev2026,
  title = {EVALUATION OF THE EFFECT OF EPITRIAZOLINE ON THE GENERAL BLOOD COUNT, BIOCHEMICAL AND MACROSCOPIC CONDITION OF THE INTERNAL ORGANS OF EXPERIMENTAL ANIMALS WITH PROLONGED ADMINISTRATION},
  author = {Zafar Sanoev and Tolmas Khamroev and Ibrohimjon Abdinazarov and Suhrob Rakhimboev and Sohib Rashidov and Dilnoza Ismailova and Burhon Elmuradov},
  journal = {Фармация ва фармакология},
  year = {2026},
  volume = {1},
  number = {15},
  pages = {130-136},
  doi = {10.66657/phcc/vol1_iss6-15/art18},
  url = {https://doi.org/10.66657/phcc/vol1_iss6-15/art18}
}

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