Abstract. Relevance. The composition of PM 2.5 aerosols varies across different cities as do the characteristics of the particles it contains. Its impact on the components of the functional tear unit cannot be ruled out, which may ultimately lead to the development of severe forms of dry eye disease (DES). Purpose of the study. To study the severity of dry eye syndrome in residents of Tashkent under conditions of elevated concentrations of fine particulate matter PM 2.5 in the atmosphere. Materials and methods. The study plans to examine a group of residents living in a specific area of Tashkent, where the levels of PM 2.5 particles in the air are regularly monitored. A homogeneous control group of 60 people from the Syrdarya region, where PM 2.5 concentrations are also measured, was selected for comparison. Results. According to the measurements, the PM 2.5 concentration in Tashkent was 28.6 μg/m3, while in the Syrdarya region it was 9.6 μg/m3. The difference in PM 2.5 concentration between the two regions was significant. Residents of Tashkent showed more pronounced symptoms of dry eye syndrome and worsened tear film parameters compared to residents of the Syrdarya region. These data suggest a possible influence of high PM 2.5 levels on the development of dry eye syndrome and the degree of ocular surface damage. Conclusion. The results of the study confirm the significant role of high PM 2.5 concentrations in the development of dry eye syndrome, its impact on tear system parameters, and the severity of ocular surface damage.
| Mualliflar | Билалов Э.Н., Орипов О.И., Хайдаров Б.Х. |
|---|---|
| Jurnal | Передовая Офтальмология |
| Nashr sanasi | 2025-05-21 |
| Jild | 11 |
| Son | 5 |
| Betlar | 20-23 |
| DOI | 10.57231/j.ao.2024.11.5.004 |
DOI: 10.57231/j.ao.2024.11.5.004 · Maqolaning asl sahifasi · PDF
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