«Ziziphora clinopodioides» Lam. is a medicinally valuable aromatic plant distributed across Central Asia, including Uzbekistan's mountain regions (Samarkand, Kashkadarya, Zomin). Despite its traditional use, the phytochemical composition of Uzbek populations remains uncharacterized. This review establishes a predictive framework for chemotypic differentiation by synthesizing global evidence on ecological and genetic drivers of chemical variability in this species. Altitude, temperature, soil, and high inter-population genetic diversity (98.31% polymorphic loci) are identified as primary determinants of essential oil and phenolic profiles. We hypothesize that Samarkand populations (moderate altitude) exhibit a pulegone-dominant chemotype, Kashkadarya populations (warmer lowlands) show increased 1,8-cineole and thymol as heat-stress adaptations, and Zomin mountain populations (high altitude) demonstrate elevated 1,8-cineole, terpinen-4-ol, and total phenolic compounds as responses to UV and oxidative stress. These predicted differences have direct implications for origin-based quality control, therapeutic application, and conservation strategies. This framework provides essential groundwork for future phytochemical characterization of «Z. clinopodioides» in Uzbekistan.
| Mualliflar | N.Q. Mukhamdiyev, Mukhamadiyev A.N., Sh. M. Sayitkulov |
|---|---|
| Jurnal | Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi |
| Nashriyot | Самарқанд давлат университети |
| ISSN | 2091-5446, 2181-1296 |
| Nashr sanasi | 2026-07-01 |
| Jild | 1 |
| Son | 3 |
| Betlar | 15-22 |
| Til | Ingliz |
| Ilmiy soha | Kimyo |
| DOI | 10.59251/2181-3973.2025.v1.138.1.3970 |
| Indeksga qo‘shilgan | 2026-09-02 |
DOI: 10.59251/2181-3973.2025.v1.138.1.3970 · Maqolaning asl sahifasi
| APA | N.Q. Mukhamdiyev, Mukhamadiyev A.N., & Sh. M. Sayitkulov (2026). ECOGEOGRAPHIC DETERMINANTS OF PHYTOCHEMICAL VARIABILITY IN «ZIZIPHORA CLINOPODIOIDES»: A PREDICTIVE FRAMEWORK FOR POPULATIONS IN UZBEKISTAN. Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(3), 15-22. https://doi.org/10.59251/2181-3973.2025.v1.138.1.3970 |
|---|---|
| GOST (OAK) | N.Q. Mukhamdiyev, Mukhamadiyev A.N., Sh. M. Sayitkulov ECOGEOGRAPHIC DETERMINANTS OF PHYTOCHEMICAL VARIABILITY IN «ZIZIPHORA CLINOPODIOIDES»: A PREDICTIVE FRAMEWORK FOR POPULATIONS IN UZBEKISTAN // Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi. – 2026. – T. 1, № 3. – P. 15-22. – DOI: 10.59251/2181-3973.2025.v1.138.1.3970. |
| MLA | N.Q. Mukhamdiyev, Mukhamadiyev A.N., and Sh. M. Sayitkulov. “ECOGEOGRAPHIC DETERMINANTS OF PHYTOCHEMICAL VARIABILITY IN «ZIZIPHORA CLINOPODIOIDES»: A PREDICTIVE FRAMEWORK FOR POPULATIONS IN UZBEKISTAN.” Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(3), 15-22, 2026. https://doi.org/10.59251/2181-3973.2025.v1.138.1.3970 |
| Chicago | N.Q. Mukhamdiyev, Mukhamadiyev A.N., and Sh. M. Sayitkulov. “ECOGEOGRAPHIC DETERMINANTS OF PHYTOCHEMICAL VARIABILITY IN «ZIZIPHORA CLINOPODIOIDES»: A PREDICTIVE FRAMEWORK FOR POPULATIONS IN UZBEKISTAN.” Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(3), 15-22 (2026). https://doi.org/10.59251/2181-3973.2025.v1.138.1.3970 |
| Harvard | N.Q. Mukhamdiyev, Mukhamadiyev A.N., and Sh. M. Sayitkulov (2026) ‘ECOGEOGRAPHIC DETERMINANTS OF PHYTOCHEMICAL VARIABILITY IN «ZIZIPHORA CLINOPODIOIDES»: A PREDICTIVE FRAMEWORK FOR POPULATIONS IN UZBEKISTAN’, Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(3), 15-22. https://doi.org/10.59251/2181-3973.2025.v1.138.1.3970 |
| BibTeX | @article{nqmukhamdiyev2026,
title = {ECOGEOGRAPHIC DETERMINANTS OF PHYTOCHEMICAL VARIABILITY IN «ZIZIPHORA CLINOPODIOIDES»: A PREDICTIVE FRAMEWORK FOR POPULATIONS IN UZBEKISTAN},
author = {N.Q. Mukhamdiyev and Mukhamadiyev A.N. and Sh. M. Sayitkulov},
journal = {Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi},
year = {2026},
volume = {1},
number = {3},
pages = {15-22},
doi = {10.59251/2181-3973.2025.v1.138.1.3970},
url = {https://doi.org/10.59251/2181-3973.2025.v1.138.1.3970}
} |
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