Postoperative cognitive dysfunction in patients with hypertension

Toshev I.I

Klinik fanlar yilnomasi · 2025-yil

Annotatsiya

Postoperative cognitive dysfunction (POCD) is a frequent and clinically significant complication observed particularly in elderly patients following major surgical interventions. It manifests as a decline in various cognitive domains, including attention, memory, processing speed, and executive function, and can persist from days to months postoperatively. Chronic hypertension induces structural and functional alterations in cerebral vasculature, such as arterial stiffness, endothelial dysfunction, and microvascular remodeling, leading to impaired cerebral autoregulation and reduced perfusion reserve. These changes make the brain more vulnerable to intraoperative hemodynamic fluctuations, hypoperfusion, and inflammatory responses triggered by anesthesia and surgical stress. Therefore, in hypertensive patients, comprehensive perioperative strategies-including preoperative cognitive assessment, individualized anesthetic plans, strict intraoperative blood pressure control, and postoperative neurocognitive monitoring—are essential to mitigate the risk and impact of POCD and to improve long-term neurological outcomes.

Maqola ma’lumotlari
MualliflarToshev I.I
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2025-08-12
Jild2
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Kalit so‘zlar

рostoperative cognitive dysfunction, hypertension, neuroinflammation, general anesthesia, cerebral perfusion, cognitive assessment., послеоперационная когнитивная дисфункция, гипертония, нейровоспаление, общая анестезия, церебральная перфузия, когнитивная оценка, операциядан кейинги когнитив дисфункция, гипертония, нейрояллиғланиш, умумий оғриқсизлантириш, мия перфузияси, когнитив баҳолаш.

Ilmiy soha

Iqtibos keltirish

APAToshev I.I (2025). POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS WITH HYPERTENSION. Klinik fanlar yilnomasi, 2(1). https://tadqiqot.uz/index.php/spjacd/article/view/12080
GOST (OAK)Toshev I.I POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS WITH HYPERTENSION // Klinik fanlar yilnomasi. – 2025. – T. 2, № 1.
MLAToshev I.I. “POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS WITH HYPERTENSION.” Klinik fanlar yilnomasi, 2(1), 2025. https://tadqiqot.uz/index.php/spjacd/article/view/12080
ChicagoToshev I.I. “POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS WITH HYPERTENSION.” Klinik fanlar yilnomasi, 2(1) (2025). https://tadqiqot.uz/index.php/spjacd/article/view/12080
HarvardToshev I.I (2025) ‘POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS WITH HYPERTENSION’, Klinik fanlar yilnomasi, 2(1). https://tadqiqot.uz/index.php/spjacd/article/view/12080
BibTeX
@article{toshevii2025,
  title = {POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS WITH HYPERTENSION},
  author = {Toshev I.I},
  journal = {Klinik fanlar yilnomasi},
  year = {2025},
  volume = {2},
  number = {1},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/12080}
}

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