This study investigated the prognostic significance of BDNF and IL-6 biomarkers and neuropsychological indicators in predicting speech recovery in patients with post-stroke aphasia. A total of 110 patients with post-stroke aphasia underwent comprehensive clinical, neurological, neuropsychological, and laboratory assessments. Aphasia severity was evaluated using the Boston Diagnostic Aphasia Examination and the Western Aphasia Battery. Serum BDNF and IL-6 levels were measured using enzyme-linked immunosorbent assay. The collected data were analyzed using correlation and regression methods. The results demonstrated a strong positive correlation between BDNF levels and speech recovery scores (r = 0.83, p < 0.001) and a strong negative correlation between IL-6 levels and speech outcomes (r = –0.91, p < 0.001). Integrated assessment of biomarkers and neuropsychological parameters enables early prediction of rehabilitation outcomes and supports the development of individualized rehabilitation strategies.
| Mualliflar | Ходжиева Дилбар Таджиевна, Хасанов Шамшод Шухратович |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashriyot | Бухоро давлат тиббиёт институти |
| Nashr sanasi | 2026-04-01 |
| Jild | 7 |
| Son | 1 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-26 |
постинсультная афазия, восстановление речи, BDNF, IL-6, биомаркеры, нейропсихологическая оценка, корреляционный анализ, нейропластичность, реабилитация, прогнозирование, post-stroke aphasia, speech recovery, BDNF, IL-6, biomarkers, neuropsychological assessment, correlation analysis, neuroplasticity, rehabilitation, prognosis, постинсульт афазия, нутқ функциясини тиклаш, BDNF, IL-6, биомаркерлар, нейропсихологик баҳолаш, корреляцион таҳлил, нейропластиклик, реабилитация, прогнозлаш
| APA | Ходжиева Дилбар Таджиевна, & Хасанов Шамшод Шухратович (2026). PROGNOSTIC SIGNIFICANCE OF BIOMARKERS AND NEUROPSYCHOLOGICAL INDICATORS IN SPEECH RECOVERY IN PATIENTS WITH POST-STROKE APHASIA. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(1). https://tadqiqot.uz/index.php/neurology/article/view/13364 |
|---|---|
| GOST (OAK) | Ходжиева Дилбар Таджиевна, Хасанов Шамшод Шухратович PROGNOSTIC SIGNIFICANCE OF BIOMARKERS AND NEUROPSYCHOLOGICAL INDICATORS IN SPEECH RECOVERY IN PATIENTS WITH POST-STROKE APHASIA // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. – 2026. – T. 7, № 1. |
| MLA | Ходжиева Дилбар Таджиевна, and Хасанов Шамшод Шухратович. “PROGNOSTIC SIGNIFICANCE OF BIOMARKERS AND NEUROPSYCHOLOGICAL INDICATORS IN SPEECH RECOVERY IN PATIENTS WITH POST-STROKE APHASIA.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(1), 2026. https://tadqiqot.uz/index.php/neurology/article/view/13364 |
| Chicago | Ходжиева Дилбар Таджиевна, and Хасанов Шамшод Шухратович. “PROGNOSTIC SIGNIFICANCE OF BIOMARKERS AND NEUROPSYCHOLOGICAL INDICATORS IN SPEECH RECOVERY IN PATIENTS WITH POST-STROKE APHASIA.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(1) (2026). https://tadqiqot.uz/index.php/neurology/article/view/13364 |
| Harvard | Ходжиева Дилбар Таджиевна, and Хасанов Шамшод Шухратович (2026) ‘PROGNOSTIC SIGNIFICANCE OF BIOMARKERS AND NEUROPSYCHOLOGICAL INDICATORS IN SPEECH RECOVERY IN PATIENTS WITH POST-STROKE APHASIA’, Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(1). https://tadqiqot.uz/index.php/neurology/article/view/13364 |
| BibTeX | @article{article2026,
title = {PROGNOSTIC SIGNIFICANCE OF BIOMARKERS AND NEUROPSYCHOLOGICAL INDICATORS IN SPEECH RECOVERY IN PATIENTS WITH POST-STROKE APHASIA},
author = {Ходжиева Дилбар Таджиевна and Хасанов Шамшод Шухратович},
journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
year = {2026},
volume = {7},
number = {1},
url = {https://tadqiqot.uz/index.php/neurology/article/view/13364}
} |
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