The gut microbiota has a significant impact on the functioning of the central nervous system, participating in the regulation of neuroinflammation, neurotransmission, neuroendocrine activity, and metabolism. Disruption of microbial homeostasis (dysbiosis) is associated with the development of various neurological and psychiatric disorders, including multiple sclerosis, Parkinson’s disease, depression, and anxiety disorders. A central element in this interaction is the “gut–brain axis,” which integrates immune, neuroendocrine, and metabolic pathways for signal transmission between the gut and the brain. Modern therapeutic approaches — such as probiotics, prebiotics, dietary interventions, and fecal microbiota transplantation — are being considered as promising strategies for microbiota modulation aimed at correcting neurological dysfunctions. In-depth study of these mechanisms opens up new opportunities for developing personalized approaches to the treatment and prevention of neurodegenerative and psychiatric disorders.
| Mualliflar | Абдуллаева Муборак Беккуловна, Абдуллаев Тоҳиржон Аъзамжон ўғли, Актамова Мадинабону Уктамовна |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashriyot | Бухоро давлат тиббиёт институти |
| Nashr sanasi | 2025-06-26 |
| Jild | 6 |
| Son | 4 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-10-05 |
микробиота кишечника, ось кишечник–мозг, дисбиоз, нейровоспаление, рассеянный склероз, депрессия, пробиотики, нейродегенерация, : gut microbiota, gut–brain axis, dysbiosis, neuroinflammation, multiple sclerosis, depression, probiotics, neurodegeneration, ичак микробиотаси, ичак–мия ўқи, дисбиоз, нейроилтиҳоб, тарқоқ склероз, депрессия, пробиотиклар, нейродегенерация
| APA | Абдуллаева Муборак Беккуловна, Абдуллаев Тоҳиржон Аъзамжон ўғли, & Актамова Мадинабону Уктамовна (2025). INFLUENCE OF INTESTINAL MICROBIOTA ON BRAIN FUNCTION AND NEUROLOGICAL DISORDERS. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(4). https://tadqiqot.uz/index.php/neurology/article/view/11646 |
|---|---|
| GOST (OAK) | Абдуллаева Муборак Беккуловна, Абдуллаев Тоҳиржон Аъзамжон ўғли, Актамова Мадинабону Уктамовна INFLUENCE OF INTESTINAL MICROBIOTA ON BRAIN FUNCTION AND NEUROLOGICAL DISORDERS // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. – 2025. – T. 6, № 4. |
| MLA | Абдуллаева Муборак Беккуловна, Абдуллаев Тоҳиржон Аъзамжон ўғли, and Актамова Мадинабону Уктамовна. “INFLUENCE OF INTESTINAL MICROBIOTA ON BRAIN FUNCTION AND NEUROLOGICAL DISORDERS.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(4), 2025. https://tadqiqot.uz/index.php/neurology/article/view/11646 |
| Chicago | Абдуллаева Муборак Беккуловна, Абдуллаев Тоҳиржон Аъзамжон ўғли, and Актамова Мадинабону Уктамовна. “INFLUENCE OF INTESTINAL MICROBIOTA ON BRAIN FUNCTION AND NEUROLOGICAL DISORDERS.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(4) (2025). https://tadqiqot.uz/index.php/neurology/article/view/11646 |
| Harvard | Абдуллаева Муборак Беккуловна, Абдуллаев Тоҳиржон Аъзамжон ўғли, and Актамова Мадинабону Уктамовна (2025) ‘INFLUENCE OF INTESTINAL MICROBIOTA ON BRAIN FUNCTION AND NEUROLOGICAL DISORDERS’, Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(4). https://tadqiqot.uz/index.php/neurology/article/view/11646 |
| BibTeX | @article{article2025,
title = {INFLUENCE OF INTESTINAL MICROBIOTA ON BRAIN FUNCTION AND NEUROLOGICAL DISORDERS},
author = {Абдуллаева Муборак Беккуловна and Абдуллаев Тоҳиржон Аъзамжон ўғли and Актамова Мадинабону Уктамовна},
journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
year = {2025},
volume = {6},
number = {4},
url = {https://tadqiqot.uz/index.php/neurology/article/view/11646}
} |
Boshqa maqola uchun iqtibos tayyorlash
The prevalence of Chiari malformation (CM) in the general population ranges from 3 to 8 cases per 100,000 people. In 64–82% of cases, this condition is accompanied by the development of syringomyelia (SM) at various…
Parkinson's disease (PD) is a common neurodegenerative disorder clinically characterized by three main symptoms: bradykinesia, resting tremor, and muscle rigidity. However, PD is a complex, heterogeneous disease with a…
Back pain is a variety of pain syndromes that develop against the background of pathological changes in the spine of varying severity. The prevalence of back pain is extremely high: according to statistics, up to 80% of…
This clinical case aims to remind general practitioners, urologists, therapists, traumatologists, orthopedists, neurosurgeons, and neurologists of the need for a more serious approach to patients presenting with…
The article presents data on the analysis of neurotrophic factors and their influence on the risk of developing cognitive impairment and dementia in patients with Parkinson's disease. A comparative assessment of Matrix…
Cervical-scapular pain syndrome (CSPS) is a painful condition associated with functional disorders of the muscles, joints and nerve tissue in the neck and shoulder areas. This syndrome can have various etiologies and is…
Degenerative spinal diseases (DSD) is one of the pressing social problems, which has a significant economic emphasis, since it affects not only older people, but also young and middle-aged people who are the working…
The article examines hippotherapy as an effective component of complex neurorehabilitation for various neurological disorders. The method is based on the biomechanical and sensorimotor effects of horse movements in a…
A clinical and neurophysiological study of tic hyperkineses in children was conducted. Eighty patients were examined and divided into three groups: the main group (with motor and vocal tics), the comparison group…
This study evaluated the effectiveness of three rehabilitation methods - physiotherapy (PT), functional electrical stimulation (FES), and transcranial magnetic stimulation (TMS) - in patients with primary and secondary…
Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research — barcha maqolalar · 2025-yil arxivi
To date, the main direction of scientific research in patients with trigeminal neuralgia is the study of the pathogenetic mechanisms of formation, resistance and subsequent neurostomatological decompensation, as well as…
Transient ischemic attacks (TIA), one of the causal factors of acute cerebrovascular disease - stroke, play an important role in the structure of cerebrovascular diseases. The difficulty in diagnosing TIA is primarily…
Facial Sympathalgia is one of the pain syndromes affecting the facial region, primarily developing in connection with dysfunction of the autonomic nervous system. This condition arises under the influence of various…
One of the most common causes of trigeminal neuralgia is vascular compression of the nerve due to abnormal vessel location or vascular changes, most often atherosclerosis. In 80-90% of cases, trigeminal neuralgia is…
In recent years, the number of patients with temporomandibular joint dysfunction pain syndrome has increased, which occurs in the majority of the adult population of developed countries: from 21.1 to 99%. This disease…
The problem of trigeminal neuralgia (TN) retains extremely social and medical importance all over the world and is one of the active factors leading to the disability of patients. TN is a disease of the chronic…
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…