Association of vitamin D receptor (VDR) gene polymorphisms with physical performance in elite athletes

Avezova, M, Rakhimova, N, Kurganov, S, Авезова, М, Рахимова, Н, Курганов, С, Авезова, М, Раҳимова, Н, Курганов, С

Тиббиёт ва спорт · 2026-yil

Annotatsiya

This study examines the association of vitamin D receptor (VDR) gene polymorphisms—rs2228570 (FokI, T>C) and rs1544410 (BsmI, G>A)—with sport-specific physical performance characteristics in 652 elite athletes representing different types of sports. Genotyping was performed using real-time PCR with allele-specific fluorescent probes. The T allele of rs2228570 was more frequently observed in athletes engaged in endurance-oriented disciplines and was associated with indicators of aerobic metabolism. In contrast, the G allele of rs1544410 was more prevalent in athletes participating in speed- and power-oriented sports, suggesting a relationship with high-intensity and technically demanding activities. The results indicate that VDR gene polymorphisms may contribute to interindividual differences in physical performance andean be considered as auxiliary genetic markers for sport-specific (raining optimization and athlete profiling.

Maqola ma’lumotlari
MualliflarAvezova, M, Rakhimova, N, Kurganov, S, Авезова, М, Рахимова, Н, Курганов, С, Авезова, М, Раҳимова, Н, Курганов, С
JurnalТиббиёт ва спорт
NashriyotЎзбекистон Миллий олимпия қўмитаси хузуридаги, Республика спорт тиббиёти илмий-амалий маркази
ISSN2181-998X
Nashr sanasi2026-05-08
Son4
Betlar28-31
TilIngliz
Ilmiy sohaBiologiya
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

ген VDR, генетический полиморфизм, физическая работоспособность, выносливость, сила, спортивная генетика, анализ генотипа, VDR gene, genetic polymorphism, physical performance, endurance, strength, sports genetics, genotype analysis, VDR гени, генетик полиморфизм, жисмоний иш қобилияти, чидамлилик, куч, спорт генетикаси, генотип таҳлили

Ilmiy soha

Biologiya

Iqtibos keltirish

APAAvezova, M, Rakhimova, N, Kurganov, S, Авезова, М, Рахимова, Н, Курганов, С, Авезова, М, Раҳимова, Н, & Курганов, С (2026). Association of vitamin D receptor (VDR) gene polymorphisms with physical performance in elite athletes. Тиббиёт ва спорт, (4), 28-31. https://journal.sportmed.uz/index.php/medsport/article/view/6
GOST (OAK)Avezova, M va b. Association of vitamin D receptor (VDR) gene polymorphisms with physical performance in elite athletes // Тиббиёт ва спорт. – 2026. – № 4. – P. 28-31.
MLAAvezova, M, Rakhimova, N, Kurganov, S, Авезова, М, Рахимова, Н, Курганов, С, Авезова, М, Раҳимова, Н, and Курганов, С. “Association of vitamin D receptor (VDR) gene polymorphisms with physical performance in elite athletes.” Тиббиёт ва спорт, (4), 28-31, 2026. https://journal.sportmed.uz/index.php/medsport/article/view/6
ChicagoAvezova, M, Rakhimova, N, Kurganov, S, Авезова, М, Рахимова, Н, Курганов, С, Авезова, М, Раҳимова, Н, and Курганов, С. “Association of vitamin D receptor (VDR) gene polymorphisms with physical performance in elite athletes.” Тиббиёт ва спорт, (4), 28-31 (2026). https://journal.sportmed.uz/index.php/medsport/article/view/6
HarvardAvezova, M, Rakhimova, N, Kurganov, S, Авезова, М, Рахимова, Н, Курганов, С, Авезова, М, Раҳимова, Н, and Курганов, С (2026) ‘Association of vitamin D receptor (VDR) gene polymorphisms with physical performance in elite athletes’, Тиббиёт ва спорт, (4), 28-31. https://journal.sportmed.uz/index.php/medsport/article/view/6
BibTeX
@article{avezovam2026,
  title = {Association of vitamin D receptor (VDR) gene polymorphisms with physical performance in elite athletes},
  author = {Avezova, M and Rakhimova, N and Kurganov, S and Авезова, М and Рахимова, Н and Курганов, С and Авезова, М and Раҳимова, Н and Курганов, С},
  journal = {Тиббиёт ва спорт},
  year = {2026},
  number = {4},
  pages = {28-31},
  url = {https://journal.sportmed.uz/index.php/medsport/article/view/6}
}

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