Contemporary approaches to myocardial infarction without coronary artery stenosis

Maxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, Kuryozov, Rasul, Макмудов, Мамуржон, Турсунов, Хурсанд, Мухамедова, Барно, Назарова, Мафтуна, Курёзов, Расул, Maxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, Kuryozov, Rasul

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-yil

Annotatsiya

Non–ST-segment elevation myocardial infarction (NSTEMI) is one of the most common forms of acute coronary syndromes and represents a leading cause of cardiovascular morbidity and mortality. In recent years, a substantial proportion of patients presenting with a clinical picture of NSTEMI have been found to have no significant coronary artery stenosis on coronary angiography; this condition is currently defined as myocardial infarction with non-obstructive coronary arteries (MINOCA). This review aims to highlight the pathogenetic mechanisms, diagnostic approaches, risk stratification, and principles of personalized management of myocardial infarction without obstructive coronary artery disease. Diagnostic and therapeutic strategies for MINOCA were analyzed based on international clinical guidelines, large registries, and systematic reviews. MINOCA is a heterogeneous syndrome encompassing multiple pathogenic mechanisms, and treatment tailored to the underlying etiology identified through contemporary imaging modalities significantly improves clinical outcomes. Comprehensive diagnostic evaluation and mechanism-oriented, personalized therapy represent the optimal clinical strategy for patients with NSTEMI presenting as MINOCA.

Maqola ma’lumotlari
MualliflarMaxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, Kuryozov, Rasul, Макмудов, Мамуржон, Турсунов, Хурсанд, Мухамедова, Барно, Назарова, Мафтуна, Курёзов, Расул, Maxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, Kuryozov, Rasul
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2025-12-24
Jild4
Son6
Betlar162-171
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-3612-2025-6-162-171
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-3612-2025-6-162-171 · Maqolaning asl sahifasi

Kalit so‘zlar

MINOCA, NSTEMI, myocardial infarction without coronary stenosis, acute coronary syndrome, high-sensitivity troponin, CMR, OCT, IVUS, MINOCA, NSTEMI, инфаркт миокарда без стеноза, рый коронарный синдром, высокочувствительный тропонин, CMR, OCT, IVUS, MINOCA, NSTEMI, stenozsiz miokard infarkti, o‘tkir koronar sindrom, yuqori sezgir troponin, CMR, OCT, IVUS

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAMaxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, Kuryozov, Rasul, Макмудов, Мамуржон, Турсунов, Хурсанд, Мухамедова, Барно, Назарова, Мафтуна, Курёзов, Расул, Maxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, & Kuryozov, Rasul (2025). CONTEMPORARY APPROACHES TO MYOCARDIAL INFARCTION WITHOUT CORONARY ARTERY STENOSIS. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 162-171. https://doi.org/10.56121/2181-3612-2025-6-162-171
GOST (OAK)Maxmudov, Mamurjon va b. CONTEMPORARY APPROACHES TO MYOCARDIAL INFARCTION WITHOUT CORONARY ARTERY STENOSIS // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 6. – P. 162-171. – DOI: 10.56121/2181-3612-2025-6-162-171.
MLAMaxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, Kuryozov, Rasul, Макмудов, Мамуржон, Турсунов, Хурсанд, Мухамедова, Барно, Назарова, Мафтуна, Курёзов, Расул, Maxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, and Kuryozov, Rasul. “CONTEMPORARY APPROACHES TO MYOCARDIAL INFARCTION WITHOUT CORONARY ARTERY STENOSIS.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 162-171, 2025. https://doi.org/10.56121/2181-3612-2025-6-162-171
ChicagoMaxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, Kuryozov, Rasul, Макмудов, Мамуржон, Турсунов, Хурсанд, Мухамедова, Барно, Назарова, Мафтуна, Курёзов, Расул, Maxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, and Kuryozov, Rasul. “CONTEMPORARY APPROACHES TO MYOCARDIAL INFARCTION WITHOUT CORONARY ARTERY STENOSIS.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 162-171 (2025). https://doi.org/10.56121/2181-3612-2025-6-162-171
HarvardMaxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, Kuryozov, Rasul, Макмудов, Мамуржон, Турсунов, Хурсанд, Мухамедова, Барно, Назарова, Мафтуна, Курёзов, Расул, Maxmudov, Mamurjon, Tursunov, Xursand, Muhamedova, Barno, Nazarova, Maftuna, and Kuryozov, Rasul (2025) ‘CONTEMPORARY APPROACHES TO MYOCARDIAL INFARCTION WITHOUT CORONARY ARTERY STENOSIS’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 162-171. https://doi.org/10.56121/2181-3612-2025-6-162-171
BibTeX
@article{maxmudovmamurjon2025,
  title = {CONTEMPORARY APPROACHES TO MYOCARDIAL INFARCTION WITHOUT CORONARY ARTERY STENOSIS},
  author = {Maxmudov, Mamurjon and Tursunov, Xursand and Muhamedova, Barno and Nazarova, Maftuna and Kuryozov, Rasul and Макмудов, Мамуржон and Турсунов, Хурсанд and Мухамедова, Барно and Назарова, Мафтуна and Курёзов, Расул and Maxmudov, Mamurjon and Tursunov, Xursand and Muhamedova, Barno and Nazarova, Maftuna and Kuryozov, Rasul},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2025},
  volume = {4},
  number = {6},
  pages = {162-171},
  doi = {10.56121/2181-3612-2025-6-162-171},
  url = {https://doi.org/10.56121/2181-3612-2025-6-162-171}
}

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