Characteristics of microelementosis as a risk factor of chronic gastroduodenal diseases in HIV-infected population

Makhsumova, Donokhon, Alibekov, Sherzodbek, Salokhiddinov, Zukhriddin, Mamasoliev, Ne’matjon, Махсумова, Д, Алибеков, Ш, Салохиддинов, З, Мамасолиев, Н, Maxsumova, Donoxon, Alibekov, Sherzodbek, Saloxiddinov, Zuxriddin, Mamasoliev, Ne’matjon

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2026-yil

Annotatsiya

Chronic gastroduodenal diseases (CGD), including peptic ulcers, chronic gastritis, and gastroduodenitis, are common among people living with HIV. One of the major risk factors associated with these conditions is microelementosis (MTOS), characterized by imbalances in essential trace elements. This study investigates the prevalence and impact of MTOS in the HIV-infected population.\\ Aim. To evaluate the prevalence, severity, and specific biochemical deficiencies associated with MTOS and its potential role as a risk factor for CGD in HIV-infected individuals. Materials and methods. This study involved 507 HIV-infected adults, aged 20–69, residing in Andijan, Uzbekistan. Participants were assessed for levels of key electrolytes, including potassium, calcium, and sodium, using fasting blood samples. Participants were categorized by age and gender to explore demographic variations in MTOS prevalence and severity.Results. The study found high rates of electrolyte deficiencies among participants, with 89.2% experiencing hyponatremia, 72.2% hypokalemia, and 28.8% hypocalcemia. Significant gender-based differences were observed, with HIV-infected women displaying higher prevalence rates of hyponatremia and hypokalemia. The data also indicated a progressive increase in the prevalence of severe MTOS with age (P < 0.05), suggesting an age-related risk for CGD. Conclusion. Microelementosis represents a significant risk factor for CGD in HIV-infected individuals, and this study underscores the need for targeted nutritional support and regular electrolyte monitoring in this population. Preventative strategies, including diet modifications and micronutrient supplementation, may help mitigate CGD progression in HIV-infected patients.

Maqola ma’lumotlari
MualliflarMakhsumova, Donokhon, Alibekov, Sherzodbek, Salokhiddinov, Zukhriddin, Mamasoliev, Ne’matjon, Махсумова, Д, Алибеков, Ш, Салохиддинов, З, Мамасолиев, Н, Maxsumova, Donoxon, Alibekov, Sherzodbek, Saloxiddinov, Zuxriddin, Mamasoliev, Ne’matjon
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2026-02-27
Jild5
Son1
Betlar32-37
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/msu-2026-1-00004
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/msu-2026-1-00004 · Maqolaning asl sahifasi

Kalit so‘zlar

Microelementosis, chronic gastroduodenal diseases, HIV infection, electrolyte imbalance, trace elements, Микроэлементоз, Хронические гастродуоденальные заболевания, ВИЧ-инфекция, Электролитный дисбаланс, Микроэлементы, Mikroelementoz, Surunkali gastroduodenal kasalliklar, VICH infektsiyasi, Elektrolit muvozanatsizligi, Mikroelementlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAMakhsumova, Donokhon, Alibekov, Sherzodbek, Salokhiddinov, Zukhriddin, Mamasoliev, Ne’matjon, Махсумова, Д, Алибеков, Ш, Салохиддинов, З, Мамасолиев, Н, Maxsumova, Donoxon, Alibekov, Sherzodbek, Saloxiddinov, Zuxriddin, & Mamasoliev, Ne’matjon (2026). Characteristics of microelementosis as a risk factor of chronic gastroduodenal diseases in HIV-infected population. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 5(1), 32-37. https://doi.org/10.56121/msu-2026-1-00004
GOST (OAK)Makhsumova, Donokhon va b. Characteristics of microelementosis as a risk factor of chronic gastroduodenal diseases in HIV-infected population // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2026. – T. 5, № 1. – P. 32-37. – DOI: 10.56121/msu-2026-1-00004.
MLAMakhsumova, Donokhon, Alibekov, Sherzodbek, Salokhiddinov, Zukhriddin, Mamasoliev, Ne’matjon, Махсумова, Д, Алибеков, Ш, Салохиддинов, З, Мамасолиев, Н, Maxsumova, Donoxon, Alibekov, Sherzodbek, Saloxiddinov, Zuxriddin, and Mamasoliev, Ne’matjon. “Characteristics of microelementosis as a risk factor of chronic gastroduodenal diseases in HIV-infected population.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 5(1), 32-37, 2026. https://doi.org/10.56121/msu-2026-1-00004
ChicagoMakhsumova, Donokhon, Alibekov, Sherzodbek, Salokhiddinov, Zukhriddin, Mamasoliev, Ne’matjon, Махсумова, Д, Алибеков, Ш, Салохиддинов, З, Мамасолиев, Н, Maxsumova, Donoxon, Alibekov, Sherzodbek, Saloxiddinov, Zuxriddin, and Mamasoliev, Ne’matjon. “Characteristics of microelementosis as a risk factor of chronic gastroduodenal diseases in HIV-infected population.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 5(1), 32-37 (2026). https://doi.org/10.56121/msu-2026-1-00004
HarvardMakhsumova, Donokhon, Alibekov, Sherzodbek, Salokhiddinov, Zukhriddin, Mamasoliev, Ne’matjon, Махсумова, Д, Алибеков, Ш, Салохиддинов, З, Мамасолиев, Н, Maxsumova, Donoxon, Alibekov, Sherzodbek, Saloxiddinov, Zuxriddin, and Mamasoliev, Ne’matjon (2026) ‘Characteristics of microelementosis as a risk factor of chronic gastroduodenal diseases in HIV-infected population’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 5(1), 32-37. https://doi.org/10.56121/msu-2026-1-00004
BibTeX
@article{makhsumovadonokhon2026,
  title = {Characteristics of microelementosis as a risk factor of chronic gastroduodenal diseases in HIV-infected population},
  author = {Makhsumova, Donokhon and Alibekov, Sherzodbek and Salokhiddinov, Zukhriddin and Mamasoliev, Ne’matjon and Махсумова, Д and Алибеков, Ш and Салохиддинов, З and Мамасолиев, Н and Maxsumova, Donoxon and Alibekov, Sherzodbek and Saloxiddinov, Zuxriddin and Mamasoliev, Ne’matjon},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2026},
  volume = {5},
  number = {1},
  pages = {32-37},
  doi = {10.56121/msu-2026-1-00004},
  url = {https://doi.org/10.56121/msu-2026-1-00004}
}

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