Importance of vitamin D3 deficiency in development of the chronic complications of diabetes

Базарова Сайёра Абдувоситовна, Нажмутдинова Дилором Камаритдиновна, Кузиева Мамура Махмудовна

Марказий Осиё эндокринологик журнали · 2025-yil

Annotatsiya

Relevance: Type 2 diabetes mellitus (DM) is a global epidemic associated with severe vascular complications development. Diabetic neuropathy is the most common chronic complication of DM that worsens patients’ life quality and prognosis. Therefore, studies dealing with DM and diabetic neuropathy underlying mechanisms are extremely relevant. The review discusses current views on vitamin D role in glucose metabolism and inflammatory processes. It is reported that vitamin D deficiency can contribute to insulin resistance development, and change in vitamin D receptor activity or extra- and intracellular calcium concentration due to vitamin D deficiency can affect pancreatic β-cells function and lead to decrease in insulin production. Key pathogenic mechanisms of diabetic neuropathy as well as possible relationship between vitamin D deficiency and neuropathy development are in focus of this review. Results of recent clinical trials regarding vitamin D supplementation in patients with DM are also discussed. The presented data suggest that vitamin D deficiency can be considered as a non-classical risk factor for the development of not only DM but its complications as well.

Maqola ma’lumotlari
MualliflarБазарова Сайёра Абдувоситовна, Нажмутдинова Дилором Камаритдиновна, Кузиева Мамура Махмудовна
JurnalМарказий Осиё эндокринологик журнали
NashriyotРеспублика ихтисослаштирилган эндокринология илмий-амалий тиббиёт маркази
ISSN2181-3426
Nashr sanasi2025-01-24
Jild4
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-06

Maqolaning asl sahifasi

Kalit so‘zlar

Диабет, диабетические осложнения, дефицит витамина D3, diabetes mellitus; diabetic neuropathy; vitamin D deficiency, Qandli diabet , diabetik asoratlar, Vitamin D 3 yetishmovchiligi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAБазарова Сайёра Абдувоситовна, Нажмутдинова Дилором Камаритдиновна, & Кузиева Мамура Махмудовна (2025). IMPORTANCE OF VITAMIN D3 DEFICIENCY IN DEVELOPMENT OF THE CHRONIC COMPLICATIONS OF DIABETES. Марказий Осиё эндокринологик журнали, 4(3). https://www.tadqiqot.uz/index.php/cae/article/view/10750
GOST (OAK)Базарова Сайёра Абдувоситовна, Нажмутдинова Дилором Камаритдиновна, Кузиева Мамура Махмудовна IMPORTANCE OF VITAMIN D3 DEFICIENCY IN DEVELOPMENT OF THE CHRONIC COMPLICATIONS OF DIABETES // Марказий Осиё эндокринологик журнали. – 2025. – T. 4, № 3.
MLAБазарова Сайёра Абдувоситовна, Нажмутдинова Дилором Камаритдиновна, and Кузиева Мамура Махмудовна. “IMPORTANCE OF VITAMIN D3 DEFICIENCY IN DEVELOPMENT OF THE CHRONIC COMPLICATIONS OF DIABETES.” Марказий Осиё эндокринологик журнали, 4(3), 2025. https://www.tadqiqot.uz/index.php/cae/article/view/10750
ChicagoБазарова Сайёра Абдувоситовна, Нажмутдинова Дилором Камаритдиновна, and Кузиева Мамура Махмудовна. “IMPORTANCE OF VITAMIN D3 DEFICIENCY IN DEVELOPMENT OF THE CHRONIC COMPLICATIONS OF DIABETES.” Марказий Осиё эндокринологик журнали, 4(3) (2025). https://www.tadqiqot.uz/index.php/cae/article/view/10750
HarvardБазарова Сайёра Абдувоситовна, Нажмутдинова Дилором Камаритдиновна, and Кузиева Мамура Махмудовна (2025) ‘IMPORTANCE OF VITAMIN D3 DEFICIENCY IN DEVELOPMENT OF THE CHRONIC COMPLICATIONS OF DIABETES’, Марказий Осиё эндокринологик журнали, 4(3). https://www.tadqiqot.uz/index.php/cae/article/view/10750
BibTeX
@article{article2025,
  title = {IMPORTANCE OF VITAMIN D3 DEFICIENCY IN DEVELOPMENT OF THE CHRONIC COMPLICATIONS OF DIABETES},
  author = {Базарова Сайёра Абдувоситовна and Нажмутдинова Дилором Камаритдиновна and Кузиева Мамура Махмудовна},
  journal = {Марказий Осиё эндокринологик журнали},
  year = {2025},
  volume = {4},
  number = {3},
  url = {https://www.tadqiqot.uz/index.php/cae/article/view/10750}
}

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