Diabetic retinal neurodegeneration

Ботирхужа Лазизхужа Бобир угли, Юлдашева Нодира Махмуджановна

Марказий Осиё эндокринологик журнали · 2025-yil

Annotatsiya

Diabetic retinopathy (DR) is recognised as the leading cause of blindness and low vision among people of working age. Diagnosis and grading of the disease is based on detection and statement, first of all, of vascular changes in the retina: haemorrhages, microaneurysms, non-vascular zones and newly formed vessels. However, in the last decade, there has been considerable research and data suggesting that retinal neurodegeneration occurs at earlier stages than vascular abnormalities. This suggests that neuronal damage may play a key role in the development of the disease and may be considered as an independent therapeutic target. This review will discuss the existing evidence and its possible clinical implications for understanding diabetic retinal neurodegeneration. Accumulating research data show that patients with qandli diabet(QD) experience progressive to’r parda thinning and visual impairment even before signs of diabetic retinopathy appear. At the same time, modern methods of to’r parda vascular imaging show signs of vascular remodelling and chorioideal changes at early stages. Histological studies of tissues from experimental animals with diabetes and in-vitro experiments confirm that QD can directly affect to’r parda nerve and glial cells, supporting the hypothesis that to’r parda neurodegeneration begins early in the disease and revealing possible disease mechanisms and potential targets for treatment.

Maqola ma’lumotlari
MualliflarБотирхужа Лазизхужа Бобир угли, Юлдашева Нодира Махмуджановна
JurnalМарказий Осиё эндокринологик журнали
NashriyotРеспублика ихтисослаштирилган эндокринология илмий-амалий тиббиёт маркази
ISSN2181-3426
Nashr sanasi2025-01-24
Jild4
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-06

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Kalit so‘zlar

Диабетическая ретинопатия, нейродегенерация, сахарный диабет,, эпидемиология, факторы риска, Diabetic retinopathy, neurodegeneration, diabetes mellitus, Epidemiology, risk factors, Diabetik retinopatiya, neyrodegeneratsiya, qandli diabet, epidemiologiya, xavf omillari

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Iqtibos keltirish

APAБотирхужа Лазизхужа Бобир угли, & Юлдашева Нодира Махмуджановна (2025). DIABETIC RETINAL NEURODEGENERATION. Марказий Осиё эндокринологик журнали, 4(3). https://www.tadqiqot.uz/index.php/cae/article/view/10746
GOST (OAK)Ботирхужа Лазизхужа Бобир угли, Юлдашева Нодира Махмуджановна DIABETIC RETINAL NEURODEGENERATION // Марказий Осиё эндокринологик журнали. – 2025. – T. 4, № 3.
MLAБотирхужа Лазизхужа Бобир угли, and Юлдашева Нодира Махмуджановна. “DIABETIC RETINAL NEURODEGENERATION.” Марказий Осиё эндокринологик журнали, 4(3), 2025. https://www.tadqiqot.uz/index.php/cae/article/view/10746
ChicagoБотирхужа Лазизхужа Бобир угли, and Юлдашева Нодира Махмуджановна. “DIABETIC RETINAL NEURODEGENERATION.” Марказий Осиё эндокринологик журнали, 4(3) (2025). https://www.tadqiqot.uz/index.php/cae/article/view/10746
HarvardБотирхужа Лазизхужа Бобир угли, and Юлдашева Нодира Махмуджановна (2025) ‘DIABETIC RETINAL NEURODEGENERATION’, Марказий Осиё эндокринологик журнали, 4(3). https://www.tadqiqot.uz/index.php/cae/article/view/10746
BibTeX
@article{article2025,
  title = {DIABETIC RETINAL NEURODEGENERATION},
  author = {Ботирхужа Лазизхужа Бобир угли and Юлдашева Нодира Махмуджановна},
  journal = {Марказий Осиё эндокринологик журнали},
  year = {2025},
  volume = {4},
  number = {3},
  url = {https://www.tadqiqot.uz/index.php/cae/article/view/10746}
}

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