Adult-onset growth hormone deficiency (GHD) remains one of the issues in clinical endocrinology. In this article, which is addressed to practitioners, physiology of growth hormone in adults is reviewed along with etiology and diagnostic criteria of this medical condition. In general, a stimulation test is required to recognize GHD. Insulin tolerance test (ITT) has been considered the gold standard by the most important scientific societies, although alternative tests, in particular GHRH plus arginine have been proposed as valuable alternative to ITT. This hormone plays a key role in regulating growth, bone formation, and overall metabolism. However, although growth hormone deficiency is often associated with childhood development, it can also occur in adults. This is a serious medical problem. Current GHD classification distinguishes patients with childhood – onset growth hormone deficiency (CO – AGHD) and adult – onset growth hormone deficiency (AO – AGHD), with an incidence of 2 in 100,000 or 1 in 10,000 per year, respectively.
| Mualliflar | Абдуллаева Азиза Ўктам қизи, Халимова Замира Юсуфовна, Холова Дилором Шарифовна, Ўралова Дилафрўз Улуғбек қизи |
|---|---|
| Jurnal | Марказий Осиё эндокринологик журнали |
| Nashr sanasi | 2024-11-06 |
| Jild | 4 |
| Son | 2 |
| Til | O‘zbek |
Соматотропная гормон, Дефицит гормон роста у взрослых (ДГРВ), инсулиноподобного фактора-1, ДЕХА, Growth hormone, Adult-onset growth hormone deficiency (AО – GHD), insulin-like growth factor – 1, DXA, Соматотроп гормон, Катталарда ўсиш гормони етишмовчилиги (КЎГЕ), ИЎО – 1, ДЕХА
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The association of negative emotions with depression and poor emotion regulation skills suggests that treatment for people with obesity and high levels of negative emotions should focus not on calorie-restricted diets…
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Objective: Changes in bone density and bone markers suggest that pregnancy is associated with poorer maternal bone mass. Calcium metabolism is restored to meet the needs associated with the construction of the fetal…