Growth hormone deficiency in adults: etiology, effects on bone structure and metabolism

Абдуллаева Азиза Ўктам қизи, Халимова Замира Юсуфовна, Холова Дилором Шарифовна, Ўралова Дилафрўз Улуғбек қизи

Марказий Осиё эндокринологик журнали · 2024-yil

Annotatsiya

Adult-onset growth hormone deficiency (GHD) remains one of the issues in clinical endocrinology. In this article, which is addressed to practitioners, physiology of growth hormone in adults is reviewed along with etiology and diagnostic criteria of this medical condition. In general, a stimulation test is required to recognize GHD. Insulin tolerance test (ITT) has been considered the gold standard by the most important scientific societies, although alternative tests, in particular GHRH plus arginine have been proposed as valuable alternative to ITT. This hormone plays a key role in regulating growth, bone formation, and overall metabolism. However, although growth hormone deficiency is often associated with childhood development, it can also occur in adults. This is a serious medical problem. Current GHD classification distinguishes patients with childhood – onset growth hormone deficiency (CO – AGHD) and adult – onset growth hormone deficiency (AO – AGHD), with an incidence of 2 in 100,000 or 1 in 10,000 per year, respectively.

Maqola ma’lumotlari
MualliflarАбдуллаева Азиза Ўктам қизи, Халимова Замира Юсуфовна, Холова Дилором Шарифовна, Ўралова Дилафрўз Улуғбек қизи
JurnalМарказий Осиё эндокринологик журнали
NashriyotРеспублика ихтисослаштирилган эндокринология илмий-амалий тиббиёт маркази
ISSN2181-3426
Nashr sanasi2024-11-06
Jild4
Son2
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-10

Maqolaning asl sahifasi

Kalit so‘zlar

Соматотропная гормон, Дефицит гормон роста у взрослых (ДГРВ), инсулиноподобного фактора-1, ДЕХА, Growth hormone, Adult-onset growth hormone deficiency (AО – GHD), insulin-like growth factor – 1, DXA, Соматотроп гормон, Катталарда ўсиш гормони етишмовчилиги (КЎГЕ), ИЎО – 1, ДЕХА

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Iqtibos keltirish

APAАбдуллаева Азиза Ўктам қизи, Халимова Замира Юсуфовна, Холова Дилором Шарифовна, & Ўралова Дилафрўз Улуғбек қизи (2024). GROWTH HORMONE DEFICIENCY IN ADULTS: ETIOLOGY, EFFECTS ON BONE STRUCTURE AND METABOLISM. Марказий Осиё эндокринологик журнали, 4(2). https://www.tadqiqot.uz/index.php/cae/article/view/10405
GOST (OAK)Абдуллаева Азиза Ўктам қизи va b. GROWTH HORMONE DEFICIENCY IN ADULTS: ETIOLOGY, EFFECTS ON BONE STRUCTURE AND METABOLISM // Марказий Осиё эндокринологик журнали. – 2024. – T. 4, № 2.
MLAАбдуллаева Азиза Ўктам қизи, Халимова Замира Юсуфовна, Холова Дилором Шарифовна, and Ўралова Дилафрўз Улуғбек қизи. “GROWTH HORMONE DEFICIENCY IN ADULTS: ETIOLOGY, EFFECTS ON BONE STRUCTURE AND METABOLISM.” Марказий Осиё эндокринологик журнали, 4(2), 2024. https://www.tadqiqot.uz/index.php/cae/article/view/10405
ChicagoАбдуллаева Азиза Ўктам қизи, Халимова Замира Юсуфовна, Холова Дилором Шарифовна, and Ўралова Дилафрўз Улуғбек қизи. “GROWTH HORMONE DEFICIENCY IN ADULTS: ETIOLOGY, EFFECTS ON BONE STRUCTURE AND METABOLISM.” Марказий Осиё эндокринологик журнали, 4(2) (2024). https://www.tadqiqot.uz/index.php/cae/article/view/10405
HarvardАбдуллаева Азиза Ўктам қизи, Халимова Замира Юсуфовна, Холова Дилором Шарифовна, and Ўралова Дилафрўз Улуғбек қизи (2024) ‘GROWTH HORMONE DEFICIENCY IN ADULTS: ETIOLOGY, EFFECTS ON BONE STRUCTURE AND METABOLISM’, Марказий Осиё эндокринологик журнали, 4(2). https://www.tadqiqot.uz/index.php/cae/article/view/10405
BibTeX
@article{article2024,
  title = {GROWTH HORMONE DEFICIENCY IN ADULTS: ETIOLOGY, EFFECTS ON BONE STRUCTURE AND METABOLISM},
  author = {Абдуллаева Азиза Ўктам қизи and Халимова Замира Юсуфовна and Холова Дилором Шарифовна and Ўралова Дилафрўз Улуғбек қизи},
  journal = {Марказий Осиё эндокринологик журнали},
  year = {2024},
  volume = {4},
  number = {2},
  url = {https://www.tadqiqot.uz/index.php/cae/article/view/10405}
}

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