Diabetic nephropathy is kidney damage in diabetes mellitus, manifested by nodular and diffuse glomerulosclerosis and in the terminal stage, chronic renal failure [37]. Diabetic nephropathy is one of the most severe complications of diabetes mellitus, leading to disability and death due to end-stage renal failure [34, 35]. According to statistics, diabetic nephropathy occurs in 20.1% of people with type 1 diabetes mellitus and 6.3% of people with type 2 diabetes mellitus [31]. However, the main pathophysiological mechanisms of the development of diabetic nephropathy are the same in both types of diabetes and are not specific [37]. Moreover, diabetic nephropathy is in third place on the list of causes of death in patients with type 2 diabetes mellitus, after cancer and cardiovascular diseases [31]. In addition, in 50-75% of patients with diabetes mellitus, the cause of death is diabetic nephropathy [13, 33, 40]. The United States spends $1.9 billion annually on treating people with type 1 diabetes, while the cost for people with type 2 diabetes is $15 billion. According to statistics provided by the United States Kidney Donor Data System, almost 520,240 people required dialysis in 2010, half of whom had type 2 diabetes [37].
| Mualliflar | Xaydarova Feruza Alimovna, Бегматова Хафиза Аширметовна, Душамова Мехрибон Шавкатовна, Ойхужаева Камилла Фаруховна |
|---|---|
| Jurnal | Марказий Осиё эндокринологик журнали |
| Nashr sanasi | 2024-11-06 |
| Jild | 4 |
| Son | 2 |
| Til | Rus |
Костно-морфогенетический белок-7, сахарный диабет, диабетическая нефропатия, скорость клубочковой фильтрации, хроническая болезнь почек, Bone morphogenetic protein-7, diabetes mellitus, diabetic nephropathy, glomerular filtration rate, chronic kidney disease, suyak-morfogenetik oqsili-7, qandli diabet, diabetik nefropatiya, ko’ptokchalar filtratsiyasi tezligi, surunkali buyrak kasalligi
Adult-onset growth hormone deficiency (GHD) remains one of the issues in clinical endocrinology. In this article, which is addressed to practitioners, physiology of growth hormone in adults is reviewed along with…
Objective: According to modern recommendations for the management of patients with type 2 diabetes, it is possible to use different combinations of hypoglycemic agents. Aim: to evaluate the effect of combination therapy…
Numerous studies have shown that active tuberculosis is detected in patients with diabetes mellitus 3-11 times more often than in the rest of the population. Currently, there are 246 million patients with diabetes…
Thyroid carcinoma (TC) in children is the most common type of endocrine cancer. Objective: to assess the thyroid status of children and adolescents with TC. Materials and methods: general clinical, biochemical, hormonal…
Purpose of the study. To study the efficacy of radiation therapy in acromegaly and to evaluate neuroimaging indices in remote periods of therapy. The object of the study was 50 patients who were on radiation therapy…
The association of negative emotions with depression and poor emotion regulation skills suggests that treatment for people with obesity and high levels of negative emotions should focus not on calorie-restricted diets…
The changes in body composition (BC) among individuals with overweight or obesity are not well understood. This study aimed to examine how BC patterns differ in this population based on age and gender. Materials and…
Objective: Changes in bone density and bone markers suggest that pregnancy is associated with poorer maternal bone mass. Calcium metabolism is restored to meet the needs associated with the construction of the fetal…
Non-functioning pituitary adenomas (NFPAs) are tumors that do not secrete hormones and can cause significant neurological and functional impairment. Despite the lack of endocrine activity, NFPAs can lead to compression…
Nodular goiter is a collective clinical concept that unites nodular formations of the thyroid gland of various morphologies. The high prevalence of iodine deficiency contributes to the development of thyroid…