“Diabetic nephropathy: problems of disease pathogenesis. Literature review"

Холиков А.Ю, Урманова Ю.М, Бердыкулова Д.М, Худойбердиева Д.Д

Марказий Осиё эндокринологик журнали · 2024-yil

Annotatsiya

The purpose of the study is to review the literature on the pathogenesis of diabetic nephropathy. Material and research methods. In order to analyze the literature, a keyword search was performed in Pubmed, Google Scholar, Scopus and other sites over the past 5-10 years. Research results. The pathogenesis of DN is very complex and is still not fully understood, which leads to poor therapeutic results. Standard therapy with strict control of blood sugar and blood pressure has been shown to fail to stop the progression of DN to terminal stage of chronic kidney disease and the mortality associated with DN. Improving understanding and studying the pathogenetic mechanisms of DN is important for the development of new treatment strategies for DN. There are multiple pathways and mediators involved in the development and progression of DN, including oxidative stress, angiotensin II (Ang-II), and inflammatory processes, which have recently been suggested to play important roles. Conclusions. A review of the literature showed that there is an urgent need to improve the understanding of the mechanism of DN and then develop new and effective therapeutic approaches to slow the progression of DN.

Maqola ma’lumotlari
MualliflarХоликов А.Ю, Урманова Ю.М, Бердыкулова Д.М, Худойбердиева Д.Д
JurnalМарказий Осиё эндокринологик журнали
NashriyotРеспублика ихтисослаштирилган эндокринология илмий-амалий тиббиёт маркази
ISSN2181-3426
Nashr sanasi2024-07-04
Jild4
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-07

Maqolaning asl sahifasi

Kalit so‘zlar

сахарный диабет 2 типа, хроническая болезнь почек, биохимические показатели, type 2 diabetes mellitus, chronic kidney disease, biochemical parameters, 2 тур қандли диабет, сурункали буйрак касаллиги, биокимёвий кўрсаткичлар

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAХоликов А.Ю, Урманова Ю.М, Бердыкулова Д.М, & Худойбердиева Д.Д (2024). “DIABETIC NEPHROPATHY: PROBLEMS OF DISEASE PATHOGENESIS. LITERATURE REVIEW". Марказий Осиё эндокринологик журнали, 4(1). https://www.tadqiqot.uz/index.php/cae/article/view/9752
GOST (OAK)Холиков А.Ю va b. “DIABETIC NEPHROPATHY: PROBLEMS OF DISEASE PATHOGENESIS. LITERATURE REVIEW" // Марказий Осиё эндокринологик журнали. – 2024. – T. 4, № 1.
MLAХоликов А.Ю, Урманова Ю.М, Бердыкулова Д.М, and Худойбердиева Д.Д. ““DIABETIC NEPHROPATHY: PROBLEMS OF DISEASE PATHOGENESIS. LITERATURE REVIEW".” Марказий Осиё эндокринологик журнали, 4(1), 2024. https://www.tadqiqot.uz/index.php/cae/article/view/9752
ChicagoХоликов А.Ю, Урманова Ю.М, Бердыкулова Д.М, and Худойбердиева Д.Д. ““DIABETIC NEPHROPATHY: PROBLEMS OF DISEASE PATHOGENESIS. LITERATURE REVIEW".” Марказий Осиё эндокринологик журнали, 4(1) (2024). https://www.tadqiqot.uz/index.php/cae/article/view/9752
HarvardХоликов А.Ю, Урманова Ю.М, Бердыкулова Д.М, and Худойбердиева Д.Д (2024) ‘“DIABETIC NEPHROPATHY: PROBLEMS OF DISEASE PATHOGENESIS. LITERATURE REVIEW"’, Марказий Осиё эндокринологик журнали, 4(1). https://www.tadqiqot.uz/index.php/cae/article/view/9752
BibTeX
@article{article2024,
  title = {“DIABETIC NEPHROPATHY: PROBLEMS OF DISEASE PATHOGENESIS. LITERATURE REVIEW"},
  author = {Холиков А.Ю and Урманова Ю.М and Бердыкулова Д.М and Худойбердиева Д.Д},
  journal = {Марказий Осиё эндокринологик журнали},
  year = {2024},
  volume = {4},
  number = {1},
  url = {https://www.tadqiqot.uz/index.php/cae/article/view/9752}
}

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