Immunohistochemical markers in the differential diagnostics of thyroid nodules

Чекманов В.Н, Муратова Ш.Т, Ли В.А, Журавлева Н.С

Марказий Осиё эндокринологик журнали · 2024-yil

Annotatsiya

Immunohistochemistry is a valuable modern, but currently little-studied method for diagnosing carcinogenesis of thyroid nodules. The article discusses such immunohistochemical markers used in the diagnosis and differential diagnosis of thyroid nodules as galectin-3, HBME-1, CK-19, TPO, CD-10. Galectin-3 has high sensitivity (from 73%) and specificity (from 81.8%). HBME-1 has higher sensitivity (94%) but lower sensitivity (77.8%) than galectin-3. CK19 is detected not only in papillary cancer, but also in follicular adenomas, and with an expression level of more than 75%, the sensitivity is 77%, and the specificity reaches 100%. Combining IGM in one panel improves sensitivity and specificity.

Maqola ma’lumotlari
MualliflarЧекманов В.Н, Муратова Ш.Т, Ли В.А, Журавлева Н.С
JurnalМарказий Осиё эндокринологик журнали
NashriyotРеспублика ихтисослаштирилган эндокринология илмий-амалий тиббиёт маркази
ISSN2181-3426
Nashr sanasi2024-07-04
Jild4
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-07

Maqolaning asl sahifasi

Kalit so‘zlar

иммуногистохимия, узлы щитовидной железы, HBME-1, CK19, Галектин-3, immunohistochemistry, thyroid nodules, HBME-1, CK19, Galectin-3, immunohistokimyo, qalqonsimon bez tugunlari, HBME-1, CK19, Galektin-3

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAЧекманов В.Н, Муратова Ш.Т, Ли В.А, & Журавлева Н.С (2024). IMMUNOHISTOCHEMICAL MARKERS IN THE DIFFERENTIAL DIAGNOSTICS OF THYROID NODULES. Марказий Осиё эндокринологик журнали, 4(1). https://www.tadqiqot.uz/index.php/cae/article/view/9755
GOST (OAK)Чекманов В.Н va b. IMMUNOHISTOCHEMICAL MARKERS IN THE DIFFERENTIAL DIAGNOSTICS OF THYROID NODULES // Марказий Осиё эндокринологик журнали. – 2024. – T. 4, № 1.
MLAЧекманов В.Н, Муратова Ш.Т, Ли В.А, and Журавлева Н.С. “IMMUNOHISTOCHEMICAL MARKERS IN THE DIFFERENTIAL DIAGNOSTICS OF THYROID NODULES.” Марказий Осиё эндокринологик журнали, 4(1), 2024. https://www.tadqiqot.uz/index.php/cae/article/view/9755
ChicagoЧекманов В.Н, Муратова Ш.Т, Ли В.А, and Журавлева Н.С. “IMMUNOHISTOCHEMICAL MARKERS IN THE DIFFERENTIAL DIAGNOSTICS OF THYROID NODULES.” Марказий Осиё эндокринологик журнали, 4(1) (2024). https://www.tadqiqot.uz/index.php/cae/article/view/9755
HarvardЧекманов В.Н, Муратова Ш.Т, Ли В.А, and Журавлева Н.С (2024) ‘IMMUNOHISTOCHEMICAL MARKERS IN THE DIFFERENTIAL DIAGNOSTICS OF THYROID NODULES’, Марказий Осиё эндокринологик журнали, 4(1). https://www.tadqiqot.uz/index.php/cae/article/view/9755
BibTeX
@article{article2024,
  title = {IMMUNOHISTOCHEMICAL MARKERS IN THE DIFFERENTIAL DIAGNOSTICS OF THYROID NODULES},
  author = {Чекманов В.Н and Муратова Ш.Т and Ли В.А and Журавлева Н.С},
  journal = {Марказий Осиё эндокринологик журнали},
  year = {2024},
  volume = {4},
  number = {1},
  url = {https://www.tadqiqot.uz/index.php/cae/article/view/9755}
}

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