Current concepts of necrotizing enterocolitis in newborns: pathogenesis, diagnosis and nutritional support

UMAROVA Nazifa Abduraufovna, SATVALDIEVA Elmira Abusamatovna, SALIKHOVA Kamola Shavkatovna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2026-yil

Annotatsiya

Objective: To systematize current knowledge on the pathogenesis, diagnosis, and nutritional support of necrotizing enterocolitis in newborns based on an analysis of domestic and international literature sources. Necrotizing enterocolitis (NEC) is a severe, multifactorial disease that predominantly affects preterm neonates and is characterized by inflammatory and necrotic damage to the intestine, with a high risk of complications and mortality. The pathogenesis involves several key mechanisms, including intestinal ischemia, alterations in the gut microbiota, immune activation, and functional immaturity of the intestinal barrier. The clinical presentation varies widely, ranging from nonspecific symptoms to severe forms with intestinal perforation and sepsis. Diagnosis is based on a combination of clinical, laboratory, and instrumental findings, commonly using the Bell staging classification. Management includes cessation of enteral feeding, antibiotic therapy, parenteral nutritional support, and surgical intervention in complicated cases. Preventive strategies play a crucial role, particularly the use of breast milk and probiotics.

Maqola ma’lumotlari
MualliflarUMAROVA Nazifa Abduraufovna, SATVALDIEVA Elmira Abusamatovna, SALIKHOVA Kamola Shavkatovna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2026-05-20
Jild11
Son2
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

некротизирующий энтероколит, новорождённые, недоношенные дети, патогенез., necrotizing enterocolitis, newborns, preterm infants, pathogenesis, nekrotizirlovchi enterokolit, yangi tug‘ilgan chaqaloqlar, muddatidan oldin tug‘ilganlar, patogenez, diagnostika, nutritiv qo‘llab-quvvatlash

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAUMAROVA Nazifa Abduraufovna, SATVALDIEVA Elmira Abusamatovna, & SALIKHOVA Kamola Shavkatovna (2026). CURRENT CONCEPTS OF NECROTIZING ENTEROCOLITIS IN NEWBORNS: PATHOGENESIS, DIAGNOSIS AND NUTRITIONAL SUPPORT. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(2). https://tadqiqot.uz/index.php/biomedicine/article/view/13892
GOST (OAK)UMAROVA Nazifa Abduraufovna, SATVALDIEVA Elmira Abusamatovna, SALIKHOVA Kamola Shavkatovna CURRENT CONCEPTS OF NECROTIZING ENTEROCOLITIS IN NEWBORNS: PATHOGENESIS, DIAGNOSIS AND NUTRITIONAL SUPPORT // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2026. – T. 11, № 2.
MLAUMAROVA Nazifa Abduraufovna, SATVALDIEVA Elmira Abusamatovna, and SALIKHOVA Kamola Shavkatovna. “CURRENT CONCEPTS OF NECROTIZING ENTEROCOLITIS IN NEWBORNS: PATHOGENESIS, DIAGNOSIS AND NUTRITIONAL SUPPORT.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(2), 2026. https://tadqiqot.uz/index.php/biomedicine/article/view/13892
ChicagoUMAROVA Nazifa Abduraufovna, SATVALDIEVA Elmira Abusamatovna, and SALIKHOVA Kamola Shavkatovna. “CURRENT CONCEPTS OF NECROTIZING ENTEROCOLITIS IN NEWBORNS: PATHOGENESIS, DIAGNOSIS AND NUTRITIONAL SUPPORT.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(2) (2026). https://tadqiqot.uz/index.php/biomedicine/article/view/13892
HarvardUMAROVA Nazifa Abduraufovna, SATVALDIEVA Elmira Abusamatovna, and SALIKHOVA Kamola Shavkatovna (2026) ‘CURRENT CONCEPTS OF NECROTIZING ENTEROCOLITIS IN NEWBORNS: PATHOGENESIS, DIAGNOSIS AND NUTRITIONAL SUPPORT’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(2). https://tadqiqot.uz/index.php/biomedicine/article/view/13892
BibTeX
@article{umarovanazifaabduraufovna2026,
  title = {CURRENT CONCEPTS OF NECROTIZING ENTEROCOLITIS IN NEWBORNS: PATHOGENESIS, DIAGNOSIS AND NUTRITIONAL SUPPORT},
  author = {UMAROVA Nazifa Abduraufovna and SATVALDIEVA Elmira Abusamatovna and SALIKHOVA Kamola Shavkatovna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2026},
  volume = {11},
  number = {2},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/13892}
}

Boshqa maqola uchun iqtibos tayyorlash

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali jurnalidan boshqa maqolalar

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar · 2026-yil arxivi

Tibbiyot sohasidagi boshqa maqolalar

Tibbiyot sohasidagi OAK jurnallari