Myosteatosis, defined as fatty infiltration of skeletal muscle, is an important component of body composition disorders in oncology. In metastatic gynecologic cancers, this condition is frequently underestimated when relying on conventional anthropometric measures, despite its significant impact on treatment tolerance and prognosis. This review summarizes current evidence on the pathophysiological mechanisms of myosteatosis, its association with chemotherapy-related toxicity, and its influence on overall and progression-free survival. Computed tomography–derived muscle density is shown to be an independent prognostic factor of adverse oncologic outcomes, particularly in patients with preserved or increased body mass index. The integration of myosteatosis assessment into multifactorial risk stratification models may improve personalized management strategies for patients with metastatic gynecologic malignancies.
| Mualliflar | SHAKHANOVA Shakhnoza Shavkatovna, KHOSHIMOV Bakhodir Bakhromovich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashriyot | Тошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ |
| ISSN | 2181-9300 |
| Nashr sanasi | 2026-05-06 |
| Jild | 11 |
| Son | 2 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-27 |
миостеатоз, онкогинекологический рак, метастазы, токсичность химиотерапии, выживаемость, компьютерная томография, myosteatosis, gynecologic cancer, metastasis, chemotherapy toxicity, survival, computed tomography, miosteatoz, onkoginekologik rak, metastazlar, kimyoterapiya toksikligi, omon qolish, kompyuter tomografiya
| APA | SHAKHANOVA Shakhnoza Shavkatovna, & KHOSHIMOV Bakhodir Bakhromovich (2026). MYOSTEATOSIS IN METASTATIC GYNECOLOGIC CANCER: CURRENT STATE OF THE PROBLEM. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(2). https://tadqiqot.uz/index.php/biomedicine/article/view/13717 |
|---|---|
| GOST (OAK) | SHAKHANOVA Shakhnoza Shavkatovna, KHOSHIMOV Bakhodir Bakhromovich MYOSTEATOSIS IN METASTATIC GYNECOLOGIC CANCER: CURRENT STATE OF THE PROBLEM // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2026. – T. 11, № 2. |
| MLA | SHAKHANOVA Shakhnoza Shavkatovna, and KHOSHIMOV Bakhodir Bakhromovich. “MYOSTEATOSIS IN METASTATIC GYNECOLOGIC CANCER: CURRENT STATE OF THE PROBLEM.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(2), 2026. https://tadqiqot.uz/index.php/biomedicine/article/view/13717 |
| Chicago | SHAKHANOVA Shakhnoza Shavkatovna, and KHOSHIMOV Bakhodir Bakhromovich. “MYOSTEATOSIS IN METASTATIC GYNECOLOGIC CANCER: CURRENT STATE OF THE PROBLEM.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(2) (2026). https://tadqiqot.uz/index.php/biomedicine/article/view/13717 |
| Harvard | SHAKHANOVA Shakhnoza Shavkatovna, and KHOSHIMOV Bakhodir Bakhromovich (2026) ‘MYOSTEATOSIS IN METASTATIC GYNECOLOGIC CANCER: CURRENT STATE OF THE PROBLEM’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(2). https://tadqiqot.uz/index.php/biomedicine/article/view/13717 |
| BibTeX | @article{shakhanovashakhnozashavkatovna2026,
title = {MYOSTEATOSIS IN METASTATIC GYNECOLOGIC CANCER: CURRENT STATE OF THE PROBLEM},
author = {SHAKHANOVA Shakhnoza Shavkatovna and KHOSHIMOV Bakhodir Bakhromovich},
journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
year = {2026},
volume = {11},
number = {2},
url = {https://tadqiqot.uz/index.php/biomedicine/article/view/13717}
} |
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