Comprehensive assessment of risk factors and optimization of management of pregnant women with cervical pathology

Juraeva N.A, Ruziyeva N.X

Жанубий оролбўйи тиббиёт журнали · 2026-yil

Annotatsiya

Objective: to perform a comprehensive assessment of clinical and laboratory risk factors and to improve the management of pregnant women with cervical pathology.Materials and Methods. The study included 120 pregnant women aged 18–45 years with cervical pathology. According to HPV status, patients were divided into three groups: Group 1 — HPV-positive patients (n=40); Group 2 — HPV-negative patients (n=40); Group 3 — control group, clinically healthy pregnant women (n=40). Clinical, cytological, colposcopic, and molecular-biological methods (PCR diagnostics of HPV, vaginal microbiota assessment using Femoflor) were used. Serum vitamin D and ferritin levels were also determined.Results. HPV infection was associated with significant disturbances of the vaginal microbiota, a high prevalence of co-infections, and deficiency of vitamin D and iron. The most significant risk factors were Gardnerella vaginalis (OR=8.9), cytomegalovirus (OR=7.8), and Ureaplasma spp. (OR=7.5). An inverse correlation between vitamin D levels and HPV infection was observed.Conclusion. Cervical pathology in pregnant women has a multifactorial nature. A comprehensive diagnostic and therapeutic approach improves treatment effectiveness and clinical outcomes.

Maqola ma’lumotlari
MualliflarJuraeva N.A, Ruziyeva N.X
JurnalЖанубий оролбўйи тиббиёт журнали
NashriyotТТА Урганч филиали
ISSN3093-8740, 2012-2021
Nashr sanasi2026-04-20
Jild2
Son2
Betlar209-214
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

pregnancy, HPV, cervix, vaginal microbiota, vitamin D

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAJuraeva N.A, & Ruziyeva N.X (2026). COMPREHENSIVE ASSESSMENT OF RISK FACTORS AND OPTIMIZATION OF MANAGEMENT OF PREGNANT WOMEN WITH CERVICAL PATHOLOGY. Жанубий оролбўйи тиббиёт журнали, 2(2), 209-214. http://journal.urdti.uz/index/article/view/533
GOST (OAK)Juraeva N.A, Ruziyeva N.X COMPREHENSIVE ASSESSMENT OF RISK FACTORS AND OPTIMIZATION OF MANAGEMENT OF PREGNANT WOMEN WITH CERVICAL PATHOLOGY // Жанубий оролбўйи тиббиёт журнали. – 2026. – T. 2, № 2. – P. 209-214.
MLAJuraeva N.A, and Ruziyeva N.X. “COMPREHENSIVE ASSESSMENT OF RISK FACTORS AND OPTIMIZATION OF MANAGEMENT OF PREGNANT WOMEN WITH CERVICAL PATHOLOGY.” Жанубий оролбўйи тиббиёт журнали, 2(2), 209-214, 2026. http://journal.urdti.uz/index/article/view/533
ChicagoJuraeva N.A, and Ruziyeva N.X. “COMPREHENSIVE ASSESSMENT OF RISK FACTORS AND OPTIMIZATION OF MANAGEMENT OF PREGNANT WOMEN WITH CERVICAL PATHOLOGY.” Жанубий оролбўйи тиббиёт журнали, 2(2), 209-214 (2026). http://journal.urdti.uz/index/article/view/533
HarvardJuraeva N.A, and Ruziyeva N.X (2026) ‘COMPREHENSIVE ASSESSMENT OF RISK FACTORS AND OPTIMIZATION OF MANAGEMENT OF PREGNANT WOMEN WITH CERVICAL PATHOLOGY’, Жанубий оролбўйи тиббиёт журнали, 2(2), 209-214. http://journal.urdti.uz/index/article/view/533
BibTeX
@article{juraevana2026,
  title = {COMPREHENSIVE ASSESSMENT OF RISK FACTORS AND OPTIMIZATION OF MANAGEMENT OF PREGNANT WOMEN WITH CERVICAL PATHOLOGY},
  author = {Juraeva N.A and Ruziyeva N.X},
  journal = {Жанубий оролбўйи тиббиёт журнали},
  year = {2026},
  volume = {2},
  number = {2},
  pages = {209-214},
  url = {http://journal.urdti.uz/index/article/view/533}
}

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