Three new esters of some ferrocenyl-containing alcohols with artesunate were synthesized, the composition and structure of which were analyzed using 1H and 13C NMR spectroscopy. An increase in the proportion of ((1S)-1-ferrocenyl)-ethylartesunate in the racemic mixture of the product to 94.1% compared with the proportion of (1S)-1-ferrocenylethanol equal to 75% in the original racemate shows that the esterification reaction (1R)-1 -ferrocenylethanol with artesunate is more difficult than with another antipode of alcohol.
| Mualliflar | Abdulloev, Obidjon Sh., Askarov, Ibragim R., Abdulloev, Shakhobidin Kh., Matamirova, Sharifa A. |
|---|---|
| Jurnal | Товарлар кимёси ва халқ табобати |
| Nashr sanasi | 2022-11-15 |
| Jild | 1 |
| Son | 5 |
| Betlar | 77-93 |
| Til | O‘zbek |
| DOI | 10.55475/jcgtm/vol1.iss5.2022.103 |
DOI: 10.55475/jcgtm/vol1.iss5.2022.103 · Maqolaning asl sahifasi
Артемизинин, артесунат, ферроценилметанол, ферроценилэтанол, ферроценилметилартесунат, ферроценилэтилартесунат, синтез, спектр ЯМР, оптический изомер, Artemisinin, artesunate, ferrocenylmethanol, ferrocenylethanol, ferrocenylmethylartesunate, ferrocenylethylartesunate, synthesis, NMR spectrum, optical isomer, Artemizinin, artesunat, ferrosenilmetanol, ferrosniletanol, ferrosenilmetilartesunat, ferrosniletilartesunat, sintez, YaMR spektri, optik izomer
The article presents a method of sorption-photometric determination of nickel ions using a new azoreagent 2-(5-methylpyridylazo-2¢-hydroxy-5¢-methoxybenzene. Optimal conditions were found: the influence of the nature…
The article presents the synthesis of new substances with urea derivatives by the diazotization method based on ferrocene carbonic acid, the methods of obtaining water-soluble derivatives of the synthesized…
Plants used in the traditional medicine contain several species of quinazoline alkaloids. In recent years, thiophene analogs of quinazoline alkaloids have been recognized as a promising class of compounds in…
In this article, the demand for plastic utensils in the world and in our country, as well as their production indicators, has been studied in detail. By studying the data on the large amount of harm caused by the…
This article provides information on the characteristics of the Lagochilus inebrians Bunge plant, its chemical composition, methods of obtaining oil extracts of the plant, the physico-chemical properties of lagolipid…
This article describes the properties, chemical composition, methods for obtaining oil extracts of the plant Lagochilus inebrians Bunge, the results of the separation and physico-chemical properties of these vegetable…
The total content of polysaccharides in the wastes of the herbs Aconitum septentrionale (AHM) and Thermopsis alterniflora (THM) was found to be 65 and 67.7% of a. d. m. of raw materials, respectively. The content of…
Arthritis is a disease of one or more joints inflammation. The chemical composition of synthetic drugs used to treat this disease and their adverse effects on other human organs have been studied. The chemical…
The article examined melon seeds by checking the vitamins in their chemical composition through the High-performance liquid chromotography method (HPLC). According to the results obtained, it was found that the melon…
This article provides information on the chemical composition, biological activity and antioxidant activity of the Askaman food additive. In contrast to the methods used by the above scientists, we studied the…