This article is devoted to the effectiveness of treating ankylosing spondylitis (AS), a chronic inflammatory disease of the musculoskeletal system. The study included 53 patients with active AS (BASDAI activity index >4) and failure of standard therapy, which included the TNF-a inhibitor infliximab (INF) at a dose of 3-5 mg/kg intravenously for 0, 2, 6 weeks and next every 8 weeks. In patients treated with INF, a positive clinical effect was achieved by indicators BASDAI and BASMI scores, as well as a remarkable positive result in dynamics vertebral mobility index and BASFI score. Tolerability of INF patients was satisfactory.
| Mualliflar | МУХАММАДИЕВА Севара Муродуллаевна, NABIEVA Dildorakhan Abdumalikovna, ZIYAEVA Feruza Kamallidinovna, MIRHAMIDOV Mirziyod Vosilzhonovich, SHIRANOVA Shakhnoza Abdinazarovna |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2023-04-28 |
| Jild | 8 |
| Son | 1 |
| Til | Rus |
анкилозирующий спондилоартрит, диагностика, лечение, ингибиторы ФНO-α, инфликсимаб, анкилозловчи спондилоартрит, диагностика, даволаш, ЎНО-α ингибиторлари, инфликсимаб
Objective: In recent times, the surgical treatment method used in arthrosis of the knee joint is to show the results of "arthroscopic imaging chondroplasty". Materials and methods: 74 patients with various stages of…
The purpose of the study was to determine the features of the damage to the structure of the head, depending on the mechanogenesis of injury from the impact of blunt objects. Materials and research methods. The analysis…
Objective: To prove the effectiveness of methods of functional treatment of congenital hip dislocation in newborns and infants. Material and methods: We analyzed the results of outpatient treatment of 102 children with…
The purpose identification of the nature, features of the course, consequences and criteria of forensic qualification of the severity of intra-articular fractures. Materials and research methods. The results of…
Target. To improve the anatomical and functional results of treatment with damage to the distal tibiofibular syndesmosis. Material and methods. For the period 2021–2022, 24 patients with damage to the distal…
The purpose. To analyze the most common classifications of mechanical injuries of the organ of vision and identify the rational one for solving the problems of forensic medical examination. Materials and research…
Objective:Improvement of clinical and instrumental methods of examination of patients with lateral instability of the knee cap. Material and methods: From 2018 to 2021, 74 patients with knee valve instability were…
Research aim: improving the treatment of chronic catarrhal gingivitis against the background of chronic calculous cholecystitis. Materials and methods. The study was conducted for the period from 2017 to 2018 at the…
Objective: Stable, reliable minimally invasive surgical treatment for damage to the anterior cruciate ligament using the "all inside" method using the tendons of the thin and semi-tendon muscles and (or) the tendon of…
The main cause of cardiovascular disease is atherosclerosis. Atherosclerosis is a chronic inflammatory vascular disease that results in the deposition of lipid plaques in the arterial wall. The accumulation and…
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