Opioid-free anesthesia for esophagoplasty in newborns: new possibilities of ultrasound-guided esp block

Gofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, Ajimamatov, Khalilulla, Гофуров, Зарифжон, Тошбоев, Шерзод, Исмаилов, Рустамбек, Ажимаматов, Халилулла, G‘ofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, Ajimamatov, Xalilulla

Халқаро илмий педиатрия журнали · 2025-yil

Annotatsiya

At the current stage of pediatric anesthesiology development, the improvement of regional anesthesia/analgesia methods as a component of multimodal anesthesia for surgical interventions in newborns is considered highly relevant. Objective.To evaluate the effectiveness and clinical applicability of ultrasound-guided ESP block in newborns undergoing esophagoplasty. Materials and methods. The ESP block was applied as a component of general anesthesia in 32 newborns with esophageal atresia. A comparative analysis was performed to assess the effectiveness of regional anesthesia with ESP block versus opioid-based general anesthesia in terms of extubation duration, ventilation requirements, and analgesia levels in the postoperative period. Hemodynamic and respiratory monitoring was carried out in all groups. Results. Among 15 full-term newborns in the main group, only 2 (6.25%) required prolonged mechanical ventilation in the postoperative period, compared to 40.6% in the group with opioid-based general anesthesia. The need for mechanical ventilation in preterm newborns was observed in both groups and amounted to 15.6% and 3.12%, respectively. Full-term newborns in the main group (n=8; 25.0%) were extubated earlier compared to the control group (n=3; 9.37%), with a statistically significant difference (p<0.05). The average time to extubation for full-term newborns in the group with general anesthesia and ESP block was 1 hour and 20 minutes (±0.95), whereas in the opioid anesthesia group, this figure reached 3 hours and 40 minutes (±1.25) (P<0.001). In preterm newborns, extubation was performed at an average of 6 hours and 20 minutes (±2.75) in the ESP block group, compared to 12 hours and 80 minutes to 3 days in the opioid anesthesia group, which was also statistically significant (P<0.001). Conclusions. Ultrasound-guided ESP block as a component of multimodal anesthesia in newborns with esophageal atresia is a safe and technically simple method. It provides adequate pain management during and after surgery, facilitates early recovery, and reduces the need for prolonged mechanical ventilation.

Maqola ma’lumotlari
MualliflarGofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, Ajimamatov, Khalilulla, Гофуров, Зарифжон, Тошбоев, Шерзод, Исмаилов, Рустамбек, Ажимаматов, Халилулла, G‘ofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, Ajimamatov, Xalilulla
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2025-02-25
Jild4
Son1
Betlar861-867
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2025-4-1-861-867
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2025-4-1-861-867 · Maqolaning asl sahifasi

Kalit so‘zlar

атрезия пищевода, анестезия, аналгезия, ESP-блокада, новорождённые, esophageal atresia, anesthesia, analgesia, ESP block, newborns, qizilo‘ngach atreziyasi, anesteziya, analgeziya, ESP-blokada, chaqaloqlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAGofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, Ajimamatov, Khalilulla, Гофуров, Зарифжон, Тошбоев, Шерзод, Исмаилов, Рустамбек, Ажимаматов, Халилулла, G‘ofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, & Ajimamatov, Xalilulla (2025). OPIOID-FREE ANESTHESIA FOR ESOPHAGOPLASTY IN NEWBORNS: NEW POSSIBILITIES OF ULTRASOUND-GUIDED ESP BLOCK. Халқаро илмий педиатрия журнали, 4(1), 861-867. https://doi.org/10.56121/2181-2926-2025-4-1-861-867
GOST (OAK)Gofurov, Zarifjon va b. OPIOID-FREE ANESTHESIA FOR ESOPHAGOPLASTY IN NEWBORNS: NEW POSSIBILITIES OF ULTRASOUND-GUIDED ESP BLOCK // Халқаро илмий педиатрия журнали. – 2025. – T. 4, № 1. – P. 861-867. – DOI: 10.56121/2181-2926-2025-4-1-861-867.
MLAGofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, Ajimamatov, Khalilulla, Гофуров, Зарифжон, Тошбоев, Шерзод, Исмаилов, Рустамбек, Ажимаматов, Халилулла, G‘ofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, and Ajimamatov, Xalilulla. “OPIOID-FREE ANESTHESIA FOR ESOPHAGOPLASTY IN NEWBORNS: NEW POSSIBILITIES OF ULTRASOUND-GUIDED ESP BLOCK.” Халқаро илмий педиатрия журнали, 4(1), 861-867, 2025. https://doi.org/10.56121/2181-2926-2025-4-1-861-867
ChicagoGofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, Ajimamatov, Khalilulla, Гофуров, Зарифжон, Тошбоев, Шерзод, Исмаилов, Рустамбек, Ажимаматов, Халилулла, G‘ofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, and Ajimamatov, Xalilulla. “OPIOID-FREE ANESTHESIA FOR ESOPHAGOPLASTY IN NEWBORNS: NEW POSSIBILITIES OF ULTRASOUND-GUIDED ESP BLOCK.” Халқаро илмий педиатрия журнали, 4(1), 861-867 (2025). https://doi.org/10.56121/2181-2926-2025-4-1-861-867
HarvardGofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, Ajimamatov, Khalilulla, Гофуров, Зарифжон, Тошбоев, Шерзод, Исмаилов, Рустамбек, Ажимаматов, Халилулла, G‘ofurov, Zarifjon, Toshboev, Sherzod, Ismailov, Rustambek, and Ajimamatov, Xalilulla (2025) ‘OPIOID-FREE ANESTHESIA FOR ESOPHAGOPLASTY IN NEWBORNS: NEW POSSIBILITIES OF ULTRASOUND-GUIDED ESP BLOCK’, Халқаро илмий педиатрия журнали, 4(1), 861-867. https://doi.org/10.56121/2181-2926-2025-4-1-861-867
BibTeX
@article{gofurovzarifjon2025,
  title = {OPIOID-FREE ANESTHESIA FOR ESOPHAGOPLASTY IN NEWBORNS: NEW POSSIBILITIES OF ULTRASOUND-GUIDED ESP BLOCK},
  author = {Gofurov, Zarifjon and Toshboev, Sherzod and Ismailov, Rustambek and Ajimamatov, Khalilulla and Гофуров, Зарифжон and Тошбоев, Шерзод and Исмаилов, Рустамбек and Ажимаматов, Халилулла and G‘ofurov, Zarifjon and Toshboev, Sherzod and Ismailov, Rustambek and Ajimamatov, Xalilulla},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2025},
  volume = {4},
  number = {1},
  pages = {861-867},
  doi = {10.56121/2181-2926-2025-4-1-861-867},
  url = {https://doi.org/10.56121/2181-2926-2025-4-1-861-867}
}

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