Emergency care for paracetamol poisoning

Zakirova, Bahora, Xusainova, Shirin, Закирова, Бахора, Хусаинова, Ширин, Zakirova, Bahora, Xusainova, Shirin

Халқаро илмий педиатрия журнали · 2025-yil

Annotatsiya

Relevance. Medicines designed to help treat diseases, if used incorrectly or in excess of dosage, can cause serious disruptions in the functioning of critical organs and even lead to death. Detecting poisoning and accurately identifying the substance that caused it is often difficult due to a lack of information about what happened. A sudden deterioration in a child’s well-being should always raise suspicion of the possibility of intoxication. The purpose of the study was to evaluate the effectiveness of N-acetylcysteine, an amino acid compound administered orally or intravenously as an antidote as part of a comprehensive emergency treatment for paracetamol intoxication. Material and methods. An analysis of the medical records of 296 children hospitalized in the Samarkand branch of the Republican Scientific Center for Emergency Medical Care with acute intoxication was carried out. Clinical data, medical history, and laboratory blood and urine tests were analyzed: liver enzyme levels (transaminases), bilirubin, alkaline phosphatase, prothrombin time, coagulation parameters, bleeding time, and urea and creatinine concentrations. During 2024, 296 patients with poisoning were admitted to the pediatric intensive care and emergency departments of Children's Hospitals No. 1 and No. 2, of which 34.1% (101 children) were affected by drug intoxication; in particular, among children under three years of age, this amounted to 22.9% or 68 cases, mainly with paracetamol poisoning. Conclusions: Thus, in case of paracetamol poisoning, the inclusion of N-acetylcysteine in complex emergency therapy in the first hours of hospitalization prevents the development of a complicated course of the disease. It is recommended to clearly instruct parents on the need to inspect the home first aid kit, as well as to deliver any suspicious packages or pills found near the child when the child’s well-being deteriorates.

Maqola ma’lumotlari
MualliflarZakirova, Bahora, Xusainova, Shirin, Закирова, Бахора, Хусаинова, Ширин, Zakirova, Bahora, Xusainova, Shirin
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2025-04-18
Jild4
Son2
Betlar891-894
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2025-4-2-891-894
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2025-4-2-891-894 · Maqolaning asl sahifasi

Kalit so‘zlar

парацетамол, антагонист, ацетилцистеин, дети, paracetamol, antagonist, acetylcysteine, children, paratsetamol, antagonist, atsetilsistein, bolalar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAZakirova, Bahora, Xusainova, Shirin, Закирова, Бахора, Хусаинова, Ширин, Zakirova, Bahora, & Xusainova, Shirin (2025). EMERGENCY CARE FOR PARACETAMOL POISONING. Халқаро илмий педиатрия журнали, 4(2), 891-894. https://doi.org/10.56121/2181-2926-2025-4-2-891-894
GOST (OAK)Zakirova, Bahora va b. EMERGENCY CARE FOR PARACETAMOL POISONING // Халқаро илмий педиатрия журнали. – 2025. – T. 4, № 2. – P. 891-894. – DOI: 10.56121/2181-2926-2025-4-2-891-894.
MLAZakirova, Bahora, Xusainova, Shirin, Закирова, Бахора, Хусаинова, Ширин, Zakirova, Bahora, and Xusainova, Shirin. “EMERGENCY CARE FOR PARACETAMOL POISONING.” Халқаро илмий педиатрия журнали, 4(2), 891-894, 2025. https://doi.org/10.56121/2181-2926-2025-4-2-891-894
ChicagoZakirova, Bahora, Xusainova, Shirin, Закирова, Бахора, Хусаинова, Ширин, Zakirova, Bahora, and Xusainova, Shirin. “EMERGENCY CARE FOR PARACETAMOL POISONING.” Халқаро илмий педиатрия журнали, 4(2), 891-894 (2025). https://doi.org/10.56121/2181-2926-2025-4-2-891-894
HarvardZakirova, Bahora, Xusainova, Shirin, Закирова, Бахора, Хусаинова, Ширин, Zakirova, Bahora, and Xusainova, Shirin (2025) ‘EMERGENCY CARE FOR PARACETAMOL POISONING’, Халқаро илмий педиатрия журнали, 4(2), 891-894. https://doi.org/10.56121/2181-2926-2025-4-2-891-894
BibTeX
@article{zakirovabahora2025,
  title = {EMERGENCY CARE FOR PARACETAMOL POISONING},
  author = {Zakirova, Bahora and Xusainova, Shirin and Закирова, Бахора and Хусаинова, Ширин and Zakirova, Bahora and Xusainova, Shirin},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2025},
  volume = {4},
  number = {2},
  pages = {891-894},
  doi = {10.56121/2181-2926-2025-4-2-891-894},
  url = {https://doi.org/10.56121/2181-2926-2025-4-2-891-894}
}

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