Innovative technologies in endovascular treatment of calcified and complex coronary lesions and LMCA revascularization strategies: a systematic literature review

Yuldashov, Bakhtiyor, Fozilov, Khurshid, Atamuratov, Bakhtiyor, Юлдашов, Б, Фозилов, Х, Атамуратов, Б, Yuldashov, Baxtiyor, Fozilov, Xurshid, Atamuratov, Baxtiyor

O‘zbekiston кardiologiyasi · 2026-yil

Annotatsiya

This systematic literature review evaluates innovative technologies for endovascular treatment of calcified and complex coronary lesions (intravascular lithotripsy, rotational and orbital atherectomy, drug-coated balloons) and left main coronary artery (LMCA) revascularization strategies (PCI versus CABG comparative analysis). Aim. To systematically assess the efficacy and safety of innovative technologies in treating calcified and complex coronary lesions, and to evaluate comparative outcomes of PCI versus CABG in LMCA disease. Methods. A systematic search of 80 scientific sources published between 2006 and 2025 was conducted using PubMed, Scopus, Web of Science, and Google Scholar databases, including major RCTs (Disrupt CAD I–IV, ROTAXUS, PREPARE-CALC, ORBIT I–II, BASKET-SMALL 2, PICCOLETO II, AGENT IDE, SYNTAX, EXCEL, NOBLE, PRECOMBAT), meta-analyses, and international consensus documents. Results. Intravascular lithotripsy (IVL) demonstrated >90% technical success with low complication rates in calcified coronary stenoses. In LMCA disease, PCI and CABG showed similar outcomes in patients with SYNTAX score ≤22, while CABG demonstrated superiority at SYNTAX score ≥33. Per IPD meta-analysis, spontaneous MI risk was 2.35-fold higher in the PCI group (p<0.0001). DCB was confirmed non-inferior to DES in small vessel disease. Conclusion. Innovative calcification modification technologies have significantly expanded treatment options for complex coronary lesions. In LMCA disease, SYNTAX score, diabetes status, and Heart Team approach are critical determinants for revascularization strategy selection.

Maqola ma’lumotlari
MualliflarYuldashov, Bakhtiyor, Fozilov, Khurshid, Atamuratov, Bakhtiyor, Юлдашов, Б, Фозилов, Х, Атамуратов, Б, Yuldashov, Baxtiyor, Fozilov, Xurshid, Atamuratov, Baxtiyor
JurnalO‘zbekiston кardiologiyasi
NashriyotЎзбекистон кардиологлар ассоциацияси
ISSN3060-4850
Nashr sanasi2026-06-29
Jild3
Son2
Betlar73-82
TilIngliz
Ilmiy sohaTibbiyot
DOI10.70626/cardiouz-2026-3-00089
Indeksga qo‘shilgan2026-10-21

DOI: 10.70626/cardiouz-2026-3-00089 · Maqolaning asl sahifasi

Kalit so‘zlar

intravascular lithotripsy, rotational atherectomy, orbital atherectomy, drug-coated balloons, left main coronary artery, percutaneous coronary intervention, coronary artery bypass grafting, coronary artery calcification, in-stent restenosisintravascular lithotripsy, in-stent restenosis, внутрисосудистая литотрипсия, ротационная атерэктомия, орбитальная атерэктомия, баллоны с лекарственным покрытием, ствол левой коронарной артерии, чрескожное коронарное вмешательство, аортокоронарное шунтирование, кальцификация коронарных артерий, внутристентовый рестеноз, tomir ichi litotripsiya, rotatsion aterektomiya, orbital aterektomiya, dori qoplamali ballonlar, chap asosiy koronar arteriya, teri orqali koronar aralashuv, aorto-koronar shuntlash, koronar arteriya kalsifikatsiyasi, stent ichi restenoz

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAYuldashov, Bakhtiyor, Fozilov, Khurshid, Atamuratov, Bakhtiyor, Юлдашов, Б, Фозилов, Х, Атамуратов, Б, Yuldashov, Baxtiyor, Fozilov, Xurshid, & Atamuratov, Baxtiyor (2026). Innovative technologies in endovascular treatment of calcified and complex coronary lesions and LMCA revascularization strategies: a systematic literature review. O‘zbekiston кardiologiyasi, 3(2), 73-82. https://doi.org/10.70626/cardiouz-2026-3-00089
GOST (OAK)Yuldashov, Bakhtiyor va b. Innovative technologies in endovascular treatment of calcified and complex coronary lesions and LMCA revascularization strategies: a systematic literature review // O‘zbekiston кardiologiyasi. – 2026. – T. 3, № 2. – P. 73-82. – DOI: 10.70626/cardiouz-2026-3-00089.
MLAYuldashov, Bakhtiyor, Fozilov, Khurshid, Atamuratov, Bakhtiyor, Юлдашов, Б, Фозилов, Х, Атамуратов, Б, Yuldashov, Baxtiyor, Fozilov, Xurshid, and Atamuratov, Baxtiyor. “Innovative technologies in endovascular treatment of calcified and complex coronary lesions and LMCA revascularization strategies: a systematic literature review.” O‘zbekiston кardiologiyasi, 3(2), 73-82, 2026. https://doi.org/10.70626/cardiouz-2026-3-00089
ChicagoYuldashov, Bakhtiyor, Fozilov, Khurshid, Atamuratov, Bakhtiyor, Юлдашов, Б, Фозилов, Х, Атамуратов, Б, Yuldashov, Baxtiyor, Fozilov, Xurshid, and Atamuratov, Baxtiyor. “Innovative technologies in endovascular treatment of calcified and complex coronary lesions and LMCA revascularization strategies: a systematic literature review.” O‘zbekiston кardiologiyasi, 3(2), 73-82 (2026). https://doi.org/10.70626/cardiouz-2026-3-00089
HarvardYuldashov, Bakhtiyor, Fozilov, Khurshid, Atamuratov, Bakhtiyor, Юлдашов, Б, Фозилов, Х, Атамуратов, Б, Yuldashov, Baxtiyor, Fozilov, Xurshid, and Atamuratov, Baxtiyor (2026) ‘Innovative technologies in endovascular treatment of calcified and complex coronary lesions and LMCA revascularization strategies: a systematic literature review’, O‘zbekiston кardiologiyasi, 3(2), 73-82. https://doi.org/10.70626/cardiouz-2026-3-00089
BibTeX
@article{yuldashovbakhtiyor2026,
  title = {Innovative technologies in endovascular treatment of calcified and complex coronary lesions and LMCA revascularization strategies: a systematic literature review},
  author = {Yuldashov, Bakhtiyor and Fozilov, Khurshid and Atamuratov, Bakhtiyor and Юлдашов, Б and Фозилов, Х and Атамуратов, Б and Yuldashov, Baxtiyor and Fozilov, Xurshid and Atamuratov, Baxtiyor},
  journal = {O‘zbekiston кardiologiyasi},
  year = {2026},
  volume = {3},
  number = {2},
  pages = {73-82},
  doi = {10.70626/cardiouz-2026-3-00089},
  url = {https://doi.org/10.70626/cardiouz-2026-3-00089}
}

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