Genes of polymorphism of vascular tone and endothelial dysfuncia in the development of pre-eclampsia in the uzbek population

Нишанова Фируза Пулатовна, Хегай Татьяна Рудольфовна, Каримова Лутфия Азизовна

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2023-yil

Annotatsiya

Preeclampsia is a serious complication of pregnancy that affects the health of both mother and fetus. The aim of the study was to study the role of the most studied gene polymorphisms responsible for the regulation of vascular tone and endothelial dysfunction with the risk of preeclampsia. The results of the study showed the presence in the NOS3 gene structure of risk (G allele/GG genotype) and protective (T allele) markers in the development of PE. The carriage of the mutant allele T of the rs1799998 polymorphism of the aldosterone synthase gene is also associated with the risk of developing PE. Haplotype analysis of these loci revealed the presence of risky TG (P=0.02, OR=1.7) and protective CT (P=0.015, OR=0.21) haplotypes in the development of PE.

Maqola ma’lumotlari
MualliflarНишанова Фируза Пулатовна, Хегай Татьяна Рудольфовна, Каримова Лутфия Азизовна
JurnalJournal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)
NashriyotСамарқанд давлат тиббиёт университети
ISSN2017-2021
Nashr sanasi2023-09-21
Jild4
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

преэклампсия, гены сосудистого тонуса, гены эндотелиальной дисфункции, preeclampsia, vascular tone genes, endothelial dysfunction genes, preeklampsiya, qon tomir tonus genlari, endotelial disfunksiya genlari

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAНишанова Фируза Пулатовна, Хегай Татьяна Рудольфовна, & Каримова Лутфия Азизовна (2023). GENES OF POLYMORPHISM OF VASCULAR TONE AND ENDOTHELIAL DYSFUNCIA IN THE DEVELOPMENT OF PRE-ECLAMPSIA IN THE UZBEK POPULATION. Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3). https://tadqiqot.uz/index.php/uro/article/view/7988
GOST (OAK)Нишанова Фируза Пулатовна, Хегай Татьяна Рудольфовна, Каримова Лутфия Азизовна GENES OF POLYMORPHISM OF VASCULAR TONE AND ENDOTHELIAL DYSFUNCIA IN THE DEVELOPMENT OF PRE-ECLAMPSIA IN THE UZBEK POPULATION // Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали). – 2023. – T. 4, № 3.
MLAНишанова Фируза Пулатовна, Хегай Татьяна Рудольфовна, and Каримова Лутфия Азизовна. “GENES OF POLYMORPHISM OF VASCULAR TONE AND ENDOTHELIAL DYSFUNCIA IN THE DEVELOPMENT OF PRE-ECLAMPSIA IN THE UZBEK POPULATION.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3), 2023. https://tadqiqot.uz/index.php/uro/article/view/7988
ChicagoНишанова Фируза Пулатовна, Хегай Татьяна Рудольфовна, and Каримова Лутфия Азизовна. “GENES OF POLYMORPHISM OF VASCULAR TONE AND ENDOTHELIAL DYSFUNCIA IN THE DEVELOPMENT OF PRE-ECLAMPSIA IN THE UZBEK POPULATION.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3) (2023). https://tadqiqot.uz/index.php/uro/article/view/7988
HarvardНишанова Фируза Пулатовна, Хегай Татьяна Рудольфовна, and Каримова Лутфия Азизовна (2023) ‘GENES OF POLYMORPHISM OF VASCULAR TONE AND ENDOTHELIAL DYSFUNCIA IN THE DEVELOPMENT OF PRE-ECLAMPSIA IN THE UZBEK POPULATION’, Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3). https://tadqiqot.uz/index.php/uro/article/view/7988
BibTeX
@article{article2023,
  title = {GENES OF POLYMORPHISM OF VASCULAR TONE AND ENDOTHELIAL DYSFUNCIA IN THE DEVELOPMENT OF PRE-ECLAMPSIA IN THE UZBEK POPULATION},
  author = {Нишанова Фируза Пулатовна and Хегай Татьяна Рудольфовна and Каримова Лутфия Азизовна},
  journal = {Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)},
  year = {2023},
  volume = {4},
  number = {3},
  url = {https://tadqiqot.uz/index.php/uro/article/view/7988}
}

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