Assessment of the microbiocenosis of the artifical vagina using the FEMOFLOR-16 test

Негмаджанов Баходур Болтаевич, Махмудова Севара Эркиновна, Ахмедов Зариф Шамсиддиновч

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2023-yil

Annotatsiya

Moderate vaginal dysbiosis is a shift in normal vaginal microbiota composition characterized by increased levels of opportunistic microbes and an ordinary high proportion of lactobacilli that make up 20 to 80 % of the total microbial population of the vagina. Some women with vaginal dysbiosis do not show any symptoms of the infectious inflammatory condition (IIC), which raises the question of whether their dysbiosis should be corrected. We studied the association between some parameters of the microbiota and clinical symptoms of IIC in female patients with moderate vaginal dysbiosis. Participants were distributed into two groups: group 1 included patients with clinical symptoms of IIC (n = 91), group 2 was comprised of asymptomatic patients (n = 44). Mean age was 26.9 ± 6.9 years. Vaginal microbial communities were studied using real-time polymerase chain reaction assays. Levels of six Lactobacillus species were measured in the vaginal discharge: Lactobacillus crispatus, L. iners, L. jensenii, L. gasseri, L. johnsonii, and L. vaginalis. We found that L. iners dominated the microbiota of 45 (49.5 %) symptomatic patients and only 9 (20.5 %) asymptomatic individuals (p = 0.002), unlike L. gasseri that significantly prevailed in the samples of asymptomatic patients: 23 (52.3 %) women vs 21 (23.1 %) in the group of patients with clinical signs of IIC (p = 0.001).

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MualliflarНегмаджанов Баходур Болтаевич, Махмудова Севара Эркиновна, Ахмедов Зариф Шамсиддиновч
JurnalJournal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)
NashriyotСамарқанд давлат тиббиёт университети
ISSN2017-2021
Nashr sanasi2023-09-21
Jild4
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

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Kalit so‘zlar

микробиоценоз влагалища, вагинальные лактобациллы, Lactobacillus iners, Lactobacillus gasseri, умеренный дисбиоз влагалища, vaginal microbiota, vaginal lactobacilli, Lactobacillus iners, Lactobacillus gasseri, moderate vaginal dysbiosis, vaginal mikrobiotsenoz, vaginal laktobakteriyalar, Lactobacillus iners, Lactobacillus gasseri, mo

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APAНегмаджанов Баходур Болтаевич, Махмудова Севара Эркиновна, & Ахмедов Зариф Шамсиддиновч (2023). ASSESSMENT OF THE MICROBIOCENOSIS OF THE ARTIFICAL VAGINA USING THE FEMOFLOR-16 TEST. Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3). https://tadqiqot.uz/index.php/uro/article/view/7985
GOST (OAK)Негмаджанов Баходур Болтаевич, Махмудова Севара Эркиновна, Ахмедов Зариф Шамсиддиновч ASSESSMENT OF THE MICROBIOCENOSIS OF THE ARTIFICAL VAGINA USING THE FEMOFLOR-16 TEST // Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали). – 2023. – T. 4, № 3.
MLAНегмаджанов Баходур Болтаевич, Махмудова Севара Эркиновна, and Ахмедов Зариф Шамсиддиновч. “ASSESSMENT OF THE MICROBIOCENOSIS OF THE ARTIFICAL VAGINA USING THE FEMOFLOR-16 TEST.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3), 2023. https://tadqiqot.uz/index.php/uro/article/view/7985
ChicagoНегмаджанов Баходур Болтаевич, Махмудова Севара Эркиновна, and Ахмедов Зариф Шамсиддиновч. “ASSESSMENT OF THE MICROBIOCENOSIS OF THE ARTIFICAL VAGINA USING THE FEMOFLOR-16 TEST.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3) (2023). https://tadqiqot.uz/index.php/uro/article/view/7985
HarvardНегмаджанов Баходур Болтаевич, Махмудова Севара Эркиновна, and Ахмедов Зариф Шамсиддиновч (2023) ‘ASSESSMENT OF THE MICROBIOCENOSIS OF THE ARTIFICAL VAGINA USING THE FEMOFLOR-16 TEST’, Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3). https://tadqiqot.uz/index.php/uro/article/view/7985
BibTeX
@article{article2023,
  title = {ASSESSMENT OF THE MICROBIOCENOSIS OF THE ARTIFICAL VAGINA USING THE FEMOFLOR-16 TEST},
  author = {Негмаджанов Баходур Болтаевич and Махмудова Севара Эркиновна and Ахмедов Зариф Шамсиддиновч},
  journal = {Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)},
  year = {2023},
  volume = {4},
  number = {3},
  url = {https://tadqiqot.uz/index.php/uro/article/view/7985}
}

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