Relevance. Keratoconus is a common asymmetric and usually bilateral ectatic corneal disease characterized by progressive corneal protrusion, resulting in reduced visual acuity and deterioration of optical properties. Purpose of the study. Was to evaluate and compare the visual, refractive and topographic results of eyes with keratoconus following corneal cross-linking with and without simultaneous intrastromal corneal segment implantation within the first 12 months. Material and methods. This prospective randomized study analyzed 38 eyes of 30 consecutive patients with keratoconus aged 26.21 ± 6.97 (range = 15–41) years. A total of 20 eyes were treated with only corneal cross-linking, and 18 eyes were treated with corneal cross-linking combined with simultaneous femtosecond-assisted intrastromal corneal segment implantation. At baseline, visual acuity, refraction and corneal topography (using a keratotopograph with a Scheimpflug camera) were assessed and compared between the two groups at 6 and 12 months. Results. At a mean follow-up of 12.2 ± 0.50 (range = 11–13) months, both corneal cross-linking and corneal cross-linking with simultaneous implantation of an intrastromal corneal segment were effective. However, corneal cross-linking plus implantation of an intrastromal corneal segment resulted in an additional improvement in uncorrected distance visual acuity by 0.16 (95% confidence interval = 0.01 to 0.32) logarithm of the minimum angle of resolution units (p = 0.035), cylindrical degree by 1.16 D (95% confidence interval = 0.25 to 2.06, p = 0.014) and spherical equivalent at 1.40 D (95% confidence interval = –2.71 to –0.08, p = 0.038) after 1 year. During the study period, no serious intraoperative or postoperative complications were noted in any group. Conclusion. One-year follow-up results show that corneal cross-linking with simultaneous combined implantation of an intrastromal corneal segment can lead to an increase in visual and refractive results. The combined procedure is safe and deserves consideration in the treatment of progressive keratoconus to achieve better visual rehabilitation.
| Mualliflar | Туйчибаева Д.М., Ким А.А. |
|---|---|
| Jurnal | Передовая Офтальмология |
| Nashr sanasi | 2025-08-13 |
| Jild | 13 |
| Son | 2 |
| Betlar | 67-74 |
| DOI | 10.57231/j.ao.2025.13.2.012 |
DOI: 10.57231/j.ao.2025.13.2.012 · Maqolaning asl sahifasi · PDF
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