Изменения со стороны поверхности глаза у пациентов с синдромом сухого глаза и атрофическим ринитом

Yusupov A.A., Khamidova F.M.

Передовая Офтальмология · 2025-yil

Annotatsiya

Relevance. Dry eye syndrome (DES) is a multifactorial disease of the ocular surface, often exacerbated by environmental and systemic conditions. Atrophic rhinitis, a chronic condition of the nasal mucosa characterized by tissue thinning and dysfunction, may influence the lacrimal system due to the anatomical and physiological connection between the nasal and ocular cavities. However, the relationship between DES and atrophic rhinitis remains underexplored. Purpose of the study. To evaluate the ocular surface status in patients with atrophic rhinitis and investigate its association with the severity of dry eye symptoms and signs. Material and methods. A total of 86 patients (172 eyes) were examined and categorized into two groups: the main group included 42 patients with clinically confirmed atrophic rhinitis, and the control group comprised 44 patients with DES without rhinitis. All participants underwent a comprehensive ophthalmic evaluation, including Norn’s test for tear film breakup time (TBUT), Schirmer’s test, the Ocular Surface Disease Index (OSDI) questionnaire, meibography, and optical coherence tomography (OCT) meniscometry. Results. TBUT was significantly shorter in patients with atrophic rhinitis compared to the control group (5.6 sec vs. 6.6 sec; p < 0.001), indicating greater tear film instability. The Schirmer’s test did not show significant differences (p > 0.05), suggesting comparable tear production. OSDI scores were higher in the main group, reflecting more pronounced subjective symptoms. Meibography changes were more marked in the main group but lacked statistical significance. OCT meniscometry revealed reduced tear meniscus height and wettability angle in patients with rhinitis. Conclusion. Patients with atrophic rhinitis exhibit more severe clinical manifestations of DES, predominantly due to tear film instability rather than aqueous deficiency. These findings underscore the importance of an interdisciplinary approach to managing such patients, considering the shared pathophysiological mechanisms between nasal and ocular surface disorders.

Maqola ma’lumotlari
MualliflarYusupov A.A., Khamidova F.M.
JurnalПередовая Офтальмология
NashriyotБухоро давлат тиббиёт институти
ISSN2181-4236, 2181-4244
Nashr sanasi2025-08-13
Jild13
Son2
Betlar87-92
TilRus
Ilmiy sohaTibbiyot
DOI10.57231/j.ao.2025.13.2.015
Indeksga qo‘shilgan2026-09-02

DOI: 10.57231/j.ao.2025.13.2.015 · Maqolaning asl sahifasi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAYusupov A.A., & Khamidova F.M. (2025). ИЗМЕНЕНИЯ СО СТОРОНЫ ПОВЕРХНОСТИ ГЛАЗА У ПАЦИЕНТОВ С СИНДРОМОМ СУХОГО ГЛАЗА И АТРОФИЧЕСКИМ РИНИТОМ. Передовая Офтальмология, 13(2), 87-92. https://doi.org/10.57231/j.ao.2025.13.2.015
GOST (OAK)Yusupov A.A., Khamidova F.M. ИЗМЕНЕНИЯ СО СТОРОНЫ ПОВЕРХНОСТИ ГЛАЗА У ПАЦИЕНТОВ С СИНДРОМОМ СУХОГО ГЛАЗА И АТРОФИЧЕСКИМ РИНИТОМ // Передовая Офтальмология. – 2025. – T. 13, № 2. – С. 87-92. – DOI: 10.57231/j.ao.2025.13.2.015.
MLAYusupov A.A., and Khamidova F.M. “ИЗМЕНЕНИЯ СО СТОРОНЫ ПОВЕРХНОСТИ ГЛАЗА У ПАЦИЕНТОВ С СИНДРОМОМ СУХОГО ГЛАЗА И АТРОФИЧЕСКИМ РИНИТОМ.” Передовая Офтальмология, 13(2), 87-92, 2025. https://doi.org/10.57231/j.ao.2025.13.2.015
ChicagoYusupov A.A., and Khamidova F.M. “ИЗМЕНЕНИЯ СО СТОРОНЫ ПОВЕРХНОСТИ ГЛАЗА У ПАЦИЕНТОВ С СИНДРОМОМ СУХОГО ГЛАЗА И АТРОФИЧЕСКИМ РИНИТОМ.” Передовая Офтальмология, 13(2), 87-92 (2025). https://doi.org/10.57231/j.ao.2025.13.2.015
HarvardYusupov A.A., and Khamidova F.M (2025) ‘ИЗМЕНЕНИЯ СО СТОРОНЫ ПОВЕРХНОСТИ ГЛАЗА У ПАЦИЕНТОВ С СИНДРОМОМ СУХОГО ГЛАЗА И АТРОФИЧЕСКИМ РИНИТОМ’, Передовая Офтальмология, 13(2), 87-92. https://doi.org/10.57231/j.ao.2025.13.2.015
BibTeX
@article{yusupovaa2025,
  title = {ИЗМЕНЕНИЯ СО СТОРОНЫ ПОВЕРХНОСТИ ГЛАЗА У ПАЦИЕНТОВ С СИНДРОМОМ СУХОГО ГЛАЗА И АТРОФИЧЕСКИМ РИНИТОМ},
  author = {Yusupov A.A. and Khamidova F.M.},
  journal = {Передовая Офтальмология},
  year = {2025},
  volume = {13},
  number = {2},
  pages = {87-92},
  doi = {10.57231/j.ao.2025.13.2.015},
  url = {https://doi.org/10.57231/j.ao.2025.13.2.015}
}

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