Morphological features of the testes of offspring born from female rats with experimentally induced hypothyroidism

Madaminova Guzal Ibragimovna, Ismailov Behruzbek Mardonovich

Klinik fanlar yilnomasi · 2026-yil

Annotatsiya

A morphological study of the testes obtained from female rats under experimental conditions showed that in the testes of 60-day-old offspring born from female rats with experimentally induced hypothyroidism, tubules with destruction and loss of spermatogenic cells were observed against the background of relatively preserved seminiferous tubules. Hypothyroidism in female rats was induced by oral administration of the antithyroid drug mercazolil at a dose of 0.5 mg per 100 g of body weight for 21 days. Hypothyroidism induced in female rats before pregnancy and persisting during pregnancy and lactation led to significant structural changes both in the developing germ cells and in Sertoli and Leydig cells of the testes of their offspring. All this indicates that maternal hypothyroidism not only disrupts spermatogenesis in the offspring but also causes significant changes in the production of steroid hormones in the testes.

Maqola ma’lumotlari
MualliflarMadaminova Guzal Ibragimovna, Ismailov Behruzbek Mardonovich
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2026-05-02
Jild3
Son1/1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

Sertoli and Leydig cells, maternal hypothyroidism, offspring, postnatal ontogenesis, spermatogenesis, spermatogonium, spermatocyte, spermatid, spermatozoon, Клетки Сертоли и Лейдига, гипотиреоз беременных, потомство, постнатальный онтогенез, сперматогенез, сперматогоний, сперматоцит, сперматид, сперматозоид, Sertoli va Leydig hujayralari, homiladorlikdagi gipotireoidizm, nasl, tug‘ruqdan keyingi ontogenez, spermatogenez, spermatogoniy, spermatosit, spermatid, spermatozoid

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAMadaminova Guzal Ibragimovna, & Ismailov Behruzbek Mardonovich (2026). MORPHOLOGICAL FEATURES OF THE TESTES OF OFFSPRING BORN FROM FEMALE RATS WITH EXPERIMENTALLY INDUCED HYPOTHYROIDISM. Klinik fanlar yilnomasi, 3(1/1). https://tadqiqot.uz/index.php/spjacd/article/view/13632
GOST (OAK)Madaminova Guzal Ibragimovna, Ismailov Behruzbek Mardonovich MORPHOLOGICAL FEATURES OF THE TESTES OF OFFSPRING BORN FROM FEMALE RATS WITH EXPERIMENTALLY INDUCED HYPOTHYROIDISM // Klinik fanlar yilnomasi. – 2026. – T. 3, № 1/1.
MLAMadaminova Guzal Ibragimovna, and Ismailov Behruzbek Mardonovich. “MORPHOLOGICAL FEATURES OF THE TESTES OF OFFSPRING BORN FROM FEMALE RATS WITH EXPERIMENTALLY INDUCED HYPOTHYROIDISM.” Klinik fanlar yilnomasi, 3(1/1), 2026. https://tadqiqot.uz/index.php/spjacd/article/view/13632
ChicagoMadaminova Guzal Ibragimovna, and Ismailov Behruzbek Mardonovich. “MORPHOLOGICAL FEATURES OF THE TESTES OF OFFSPRING BORN FROM FEMALE RATS WITH EXPERIMENTALLY INDUCED HYPOTHYROIDISM.” Klinik fanlar yilnomasi, 3(1/1) (2026). https://tadqiqot.uz/index.php/spjacd/article/view/13632
HarvardMadaminova Guzal Ibragimovna, and Ismailov Behruzbek Mardonovich (2026) ‘MORPHOLOGICAL FEATURES OF THE TESTES OF OFFSPRING BORN FROM FEMALE RATS WITH EXPERIMENTALLY INDUCED HYPOTHYROIDISM’, Klinik fanlar yilnomasi, 3(1/1). https://tadqiqot.uz/index.php/spjacd/article/view/13632
BibTeX
@article{madaminovaguzalibragimovna2026,
  title = {MORPHOLOGICAL FEATURES OF THE TESTES OF OFFSPRING BORN FROM FEMALE RATS WITH EXPERIMENTALLY INDUCED HYPOTHYROIDISM},
  author = {Madaminova Guzal Ibragimovna and Ismailov Behruzbek Mardonovich},
  journal = {Klinik fanlar yilnomasi},
  year = {2026},
  volume = {3},
  number = {1/1},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/13632}
}

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