The aim of the study was to investigate structural and functional changes in skeletal muscle after botulinum therapy in children with cerebral palsy (CP) based on clinical, electrophysiological, and functional parameters. A prospective clinical and physiological study was conducted with assessment of spasticity dynamics, motor function, and electromyographic characteristics of target muscles before and after administration of botulinum toxin type A. The obtained data indicate that botulinum therapy initiates a complex remodeling of skeletal muscle, including reduction of pathological activity, decreased muscle co-activation, and functional remodeling, thereby creating conditions for the restoration of motor patterns and improving the effectiveness of rehabilitation.
| Mualliflar | Majidova Nozila Usmon qizi, Botirova Nigina Botirovna, Omonov Shohjahon Asrorovich, Madjidova Yakutkhon Nabiyevna |
|---|---|
| Jurnal | Klinik fanlar yilnomasi |
| Nashr sanasi | 2026-05-02 |
| Jild | 3 |
| Son | 1/1 |
| Til | Ingliz |
cerebral palsy, botulinum therapy, skeletal muscle, structural and functional remodeling, EMG, spasticity, детский церебральный паралич, ботулинотерапия, скелетная мышца, структурно-функциональная перестройка, ЭНМГ, спастичность, bolalar serebral falaji, botulinoterapiya, skelet mushagi, strukturaviy va funksional remodellashtirish, EMG, spastiklik
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