Paclitaxel used in chemotherapy of breast cancer is an inhibitor of mitosis and is obtained from plants. They block cell division, disrupt the function of microtubules and some enzyme proteins. They change the metabolism of amino acids and some other substances, such as nucleic acids, fat synthesis, and also affect cellular respiration. When we modeled breast cancer in 6-month-old rats and carried out chemotherapy using paclitaxel, we encountered various pathomorphological changes.
| Mualliflar | Khalikova Feruza Sharofovna |
|---|---|
| Jurnal | Klinik fanlar yilnomasi |
| Nashr sanasi | 2025-10-30 |
| Jild | 2 |
| Son | 3/1 |
| Til | Ingliz |
Cancer, chemotherapy, follicle, theriocyte, hormone, B-cell, C-cell, thyroid substance, epithelium, stroma, parenchyma, Рак, химиотерапия, фолликул, териоцит, гормон, В-клетка, С-клетка, тиреоидное вещество, эпителий, строма, паренхима., Saraton, kimyoterapiya, follikula, teriotsit, garmon, B-hujayra, C-hujayra, teroid modda, epiteliy, stroma, parenxima
Chronic hepatitis B (CHB) remains a significant global health burden, with liver fibrosis progression being a critical determinant of patient outcomes. Traditional liver biopsy, while considered the gold standard…
The development of complex pathogenetic treatment methods for TORCH infections associated with mixed infection and the improvement of differential approaches remain one of the urgent problems that need to be solved. A…
This study investigated the effectiveness of BAC in cognitive rehabilitation in post-stroke patients. Dynamic examination of 48 patients with cognitive impairment at the second stage of rehabilitation was performed. The…
This article explores the advantages of a student-centered approach in teaching clinical pharmacology and the innovative methods for its implementation in practice. Unlike traditional teaching methods, the…
This study evaluated the effect of SGLT-2 inhibitors on liver fibrosis indices (Fib-4, NAFLD fibrosis score) and insulin resistance (HOMA-IR) in patients with type 2 diabetes, as well as the correlation between these…
Currently, chemical burns of various degrees of the digestive system are a very urgent medical, social and economic problem. Severe burns of the upper gastrointestinal tract occur in 10-33% of adult patients, with a…
This article presents the results of a scientific study aimed at evaluating the significance and effectiveness of the Mediterranean diet in preventing exacerbations of chronic pancreatitis among the population of…
This article explores the clinical evaluation of internal knee joint structures (menisci, ligaments, synovial membrane, etc.) using ultrasonography. The diagnostic advantages of ultrasound—such as high sensitivity…
This article analyzes the clinical features of nephrotic syndrome in children, the factors influencing its development, and the ways to improve preventive measures, using the Fergana region as an example. The role of…
The rise of electromechanical mobility devices has increased maxillofacial trauma. This study analyzed force propagation through craniofacial buttresses under atypical loading from such impacts using a hybrid approach…