Dynamics of liver fibrosis markers and insulin resistance during treatment with sodium–glucose cotransporter 2 (SGLT-2) inhibitors

Najmutdinova Dilorom Qamardinovna, Ismoilova Shaxnoza Samandarovna

Klinik fanlar yilnomasi · 2025-yil

Annotatsiya

This study evaluated the effect of SGLT-2 inhibitors on liver fibrosis indices (Fib-4, NAFLD fibrosis score) and insulin resistance (HOMA-IR) in patients with type 2 diabetes, as well as the correlation between these variables. The results demonstrated a statistically significant decrease in Fib-4 and NFS values following therapy, along with a strong positive correlation between fibrosis indices and HOMA-IR (ρ >0.85; p < 0.001). These findings support the hepatoprotective and metabolic effects of SGLT-2 inhibitors.

Maqola ma’lumotlari
MualliflarNajmutdinova Dilorom Qamardinovna, Ismoilova Shaxnoza Samandarovna
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2025-10-30
Jild2
Son3/1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

Type 2 diabetes mellitus, MAYJK, SGLT-2 inhibitors, Fib-4, liver fibrosis, NAFLD fibrosis score, insulin resistancy, сахарный диабет 2 типа, МАЖБП, ингибиторы SGLT-2, индекс Fib-4, фиброз печени, индекс фиброза, инсулинорезистентность, 2-tip qandli diabet, MAYJK, SGLT-2 ingibitorlari, Fib-4, jigar fibrozi, NAFLD fibroz indeksi, insulin rezistentlik

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APANajmutdinova Dilorom Qamardinovna, & Ismoilova Shaxnoza Samandarovna (2025). DYNAMICS OF LIVER FIBROSIS MARKERS AND INSULIN RESISTANCE DURING TREATMENT WITH SODIUM–GLUCOSE COTRANSPORTER 2 (SGLT-2) INHIBITORS. Klinik fanlar yilnomasi, 2(3/1). https://tadqiqot.uz/index.php/spjacd/article/view/12621
GOST (OAK)Najmutdinova Dilorom Qamardinovna, Ismoilova Shaxnoza Samandarovna DYNAMICS OF LIVER FIBROSIS MARKERS AND INSULIN RESISTANCE DURING TREATMENT WITH SODIUM–GLUCOSE COTRANSPORTER 2 (SGLT-2) INHIBITORS // Klinik fanlar yilnomasi. – 2025. – T. 2, № 3/1.
MLANajmutdinova Dilorom Qamardinovna, and Ismoilova Shaxnoza Samandarovna. “DYNAMICS OF LIVER FIBROSIS MARKERS AND INSULIN RESISTANCE DURING TREATMENT WITH SODIUM–GLUCOSE COTRANSPORTER 2 (SGLT-2) INHIBITORS.” Klinik fanlar yilnomasi, 2(3/1), 2025. https://tadqiqot.uz/index.php/spjacd/article/view/12621
ChicagoNajmutdinova Dilorom Qamardinovna, and Ismoilova Shaxnoza Samandarovna. “DYNAMICS OF LIVER FIBROSIS MARKERS AND INSULIN RESISTANCE DURING TREATMENT WITH SODIUM–GLUCOSE COTRANSPORTER 2 (SGLT-2) INHIBITORS.” Klinik fanlar yilnomasi, 2(3/1) (2025). https://tadqiqot.uz/index.php/spjacd/article/view/12621
HarvardNajmutdinova Dilorom Qamardinovna, and Ismoilova Shaxnoza Samandarovna (2025) ‘DYNAMICS OF LIVER FIBROSIS MARKERS AND INSULIN RESISTANCE DURING TREATMENT WITH SODIUM–GLUCOSE COTRANSPORTER 2 (SGLT-2) INHIBITORS’, Klinik fanlar yilnomasi, 2(3/1). https://tadqiqot.uz/index.php/spjacd/article/view/12621
BibTeX
@article{najmutdinovadiloromqamardinovna2025,
  title = {DYNAMICS OF LIVER FIBROSIS MARKERS AND INSULIN RESISTANCE DURING TREATMENT WITH SODIUM–GLUCOSE COTRANSPORTER 2 (SGLT-2) INHIBITORS},
  author = {Najmutdinova Dilorom Qamardinovna and Ismoilova Shaxnoza Samandarovna},
  journal = {Klinik fanlar yilnomasi},
  year = {2025},
  volume = {2},
  number = {3/1},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/12621}
}

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