Chronic cerebral ischemia remains one of the leading problems in modern neurology due to the high prevalence of cerebrovascular pathology and associated cognitive impairment. In recent years, special attention has been paid to cerebral perfusion disorders as a key mechanism in the pathogenesis of chronic cerebral ischemia. Modern neuroimaging techniques allow assessment of cerebral blood flow, microcirculatory disturbances, and structural brain damage. The article reviews current concepts of cerebral hypoperfusion, endothelial dysfunction, neuroinflammation, and microangiopathy in the development of vascular cognitive impairment. The diagnostic value of MR perfusion imaging, arterial spin labeling MRI, CT perfusion, and other neuroimaging biomarkers is discussed.
| Mualliflar | Рахимбаева Гульнора Саттаровна, Мирхаетова Нозимахон Анвар кизи |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashriyot | Бухоро давлат тиббиёт институти |
| Nashr sanasi | 2026-06-22 |
| Jild | 7 |
| Son | 4 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-26 |
хроническая ишемия мозга, церебральная перфузия, сосудистые когнитивные нарушения, нейровизуализация, ASL-МРТ, микроангиопатия, гипоперфузия, chronic cerebral ischemia, cerebral perfusion, vascular cognitive impairment, neuroimaging, ASL-MRI, microangiopathy, hypoperfusion, surunkali miya ishemiyasi, serebral perfuziya, tomirli kognitiv buzilishlar, neyrovizualizatsiya, ASL-MRT, mikroangiopatiya.
| APA | Рахимбаева Гульнора Саттаровна, & Мирхаетова Нозимахон Анвар кизи (2026). CEREBRAL PERFUSION IN CHRONIC BRAIN ISCHEMIA: CONTEMPORARY CONCEPTS OF PATHOGENESIS, NEUROIMAGING BIOMARKERS, AND VASCULAR COGNITIVE IMPAIRMENT. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(4). https://tadqiqot.uz/index.php/neurology/article/view/14300 |
|---|---|
| GOST (OAK) | Рахимбаева Гульнора Саттаровна, Мирхаетова Нозимахон Анвар кизи CEREBRAL PERFUSION IN CHRONIC BRAIN ISCHEMIA: CONTEMPORARY CONCEPTS OF PATHOGENESIS, NEUROIMAGING BIOMARKERS, AND VASCULAR COGNITIVE IMPAIRMENT // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. – 2026. – T. 7, № 4. |
| MLA | Рахимбаева Гульнора Саттаровна, and Мирхаетова Нозимахон Анвар кизи. “CEREBRAL PERFUSION IN CHRONIC BRAIN ISCHEMIA: CONTEMPORARY CONCEPTS OF PATHOGENESIS, NEUROIMAGING BIOMARKERS, AND VASCULAR COGNITIVE IMPAIRMENT.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(4), 2026. https://tadqiqot.uz/index.php/neurology/article/view/14300 |
| Chicago | Рахимбаева Гульнора Саттаровна, and Мирхаетова Нозимахон Анвар кизи. “CEREBRAL PERFUSION IN CHRONIC BRAIN ISCHEMIA: CONTEMPORARY CONCEPTS OF PATHOGENESIS, NEUROIMAGING BIOMARKERS, AND VASCULAR COGNITIVE IMPAIRMENT.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(4) (2026). https://tadqiqot.uz/index.php/neurology/article/view/14300 |
| Harvard | Рахимбаева Гульнора Саттаровна, and Мирхаетова Нозимахон Анвар кизи (2026) ‘CEREBRAL PERFUSION IN CHRONIC BRAIN ISCHEMIA: CONTEMPORARY CONCEPTS OF PATHOGENESIS, NEUROIMAGING BIOMARKERS, AND VASCULAR COGNITIVE IMPAIRMENT’, Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(4). https://tadqiqot.uz/index.php/neurology/article/view/14300 |
| BibTeX | @article{article2026,
title = {CEREBRAL PERFUSION IN CHRONIC BRAIN ISCHEMIA: CONTEMPORARY CONCEPTS OF PATHOGENESIS, NEUROIMAGING BIOMARKERS, AND VASCULAR COGNITIVE IMPAIRMENT},
author = {Рахимбаева Гульнора Саттаровна and Мирхаетова Нозимахон Анвар кизи},
journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
year = {2026},
volume = {7},
number = {4},
url = {https://tadqiqot.uz/index.php/neurology/article/view/14300}
} |
Boshqa maqola uchun iqtibos tayyorlash
Objective. To identify specific clinical features and neurophysiological correlates of affective respiratory attacks (ARAs) in young children with concomitant iron deficiency anemia (IDA). Methods. In a comparative…
В данной статье приведены результаты собственных исследований результатов при дуплексном сканировании сосудов шеи, транскраниальной допплерографии сосудов головного мозга у больных с ВБН. При изучении венозного…
The article presents the results of a comparative clinical and laboratory study focusing on the systemic inflammatory response in patients with degenerative and vascular forms of parkinsonism. Serum interleukin-6…
Neurogenic deformities in children remain an important challenge in pediatric neurology, orthopedics and rehabilitation medicine. Deformities caused by central and peripheral nervous system disorders lead to motor…
This systematic review was conducted according to the PRISMA 2020 guidelines to identify English-language studies published within the past 5 years (2020–2025) reporting awake craniotomy (with intraoperative mapping)…
Objective: To investigate the role of iron metabolism disorders and ferroptosis mechanisms in the pathogenesis of symptomatic epilepsy. Materials and methods: A prospective controlled cohort study was conducted…
A prospective comparative clinical study included 120 patients who underwent microdiscectomy or endoscopic discectomy for L4–L5 and L5–S1 disc herniations. Patients were divided into two groups: a standard…
Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord compression and its subsequent degeneration in adults. Despite the fact that surgical decompression is the main method of treatment for…
Objective: To evaluate the effectiveness of a personalized prevention strategy for recurrent hemorrhagic stroke in primary healthcare settings. Materials and methods: A prospective controlled study was conducted…
The article presents the results of a study on psychoemotional disorders and the characteristics of micronutrient status in athletes with different levels of internet addiction. The study involved 96 athletes aged…
Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research — barcha maqolalar · 2026-yil arxivi
This article highlights the difference between efficiency of dual antiplatelet therapy and antiplatelet monotherapy in 60 patients with ischemic stroke.
Stroke is the most common vascular disease of the brain, which in most cases ends in death or is the cause of profound disability in patients (13). This is not only a medical but also a social problem (13). One of the…
This article evaluates the predictive role of insulin resistance and inflammatory biomarkers in patients with acute ischemic stroke. The study demonstrates that biomarker concentrations vary across stroke subtypes and…
Amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's disease, is a chronic, slowly progressive disease in which the leading clinical syndromes are spastic-atrophic paresis of the…
In the context of COVID-19, stroke has proven to be a relatively common complication. The presence of cerebrovascular disease is an independent risk factor for poor prognosis in patients with severe COVID-19. The…
Obstructive sleep apnea (OSA) is recognized as an independent risk factor for the development of cognitive impairment. Recent evidence (Andreu et al., Sleep Medicine Reviews, 2024) [1]. indicates that intermittent…
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…