CEREBRAL PERFUSION IN CHRONIC BRAIN ISCHEMIA: CONTEMPORARY CONCEPTS OF PATHOGENESIS, NEUROIMAGING BIOMARKERS, AND VASCULAR COGNITIVE IMPAIRMENT

Рахимбаева Гульнора Саттаровна, Мирхаетова Нозимахон Анвар кизи

Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2026-yil

Annotatsiya

Chronic cerebral ischemia remains one of the leading problems in modern neurology due to the high prevalence of cerebrovascular pathology and associated cognitive impairment. In recent years, special attention has been paid to cerebral perfusion disorders as a key mechanism in the pathogenesis of chronic cerebral ischemia. Modern neuroimaging techniques allow assessment of cerebral blood flow, microcirculatory disturbances, and structural brain damage. The article reviews current concepts of cerebral hypoperfusion, endothelial dysfunction, neuroinflammation, and microangiopathy in the development of vascular cognitive impairment. The diagnostic value of MR perfusion imaging, arterial spin labeling MRI, CT perfusion, and other neuroimaging biomarkers is discussed.

Maqola ma’lumotlari
MualliflarРахимбаева Гульнора Саттаровна, Мирхаетова Нозимахон Анвар кизи
JurnalЖурнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research
Nashr sanasi2026-06-22
Jild7
Son4
TilRus

Kalit so‘zlar

хроническая ишемия мозга, церебральная перфузия, сосудистые когнитивные нарушения, нейровизуализация, ASL-МРТ, микроангиопатия, гипоперфузия, chronic cerebral ischemia, cerebral perfusion, vascular cognitive impairment, neuroimaging, ASL-MRI, microangiopathy, hypoperfusion, surunkali miya ishemiyasi, serebral perfuziya, tomirli kognitiv buzilishlar, neyrovizualizatsiya, ASL-MRT, mikroangiopatiya.

Ilmiy soha

Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research jurnalidan boshqa maqolalar

Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research — barcha maqolalar