Specifics of clinical manifestations and neurophysiological correlates of affective respiratory attacks in children with iron deficiency anemia

Маджидова Ёкутхон Набиевна, Адамбаев Зуфар Ибрагимович, Камолдинова Дилдора Бахтияровна

Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2026-yil

Annotatsiya

Objective. To identify specific clinical features and neurophysiological correlates of affective respiratory attacks (ARAs) in young children with concomitant iron deficiency anemia (IDA). Methods. In a comparative study, 120 children aged 1 to 5 years with verified ARAs were examined, divided into two groups: the main group (n=60, ARA with IDA) and the control group (n=60, ARA without iron metabolism disorders). The clinical picture, neurological status, heart rate variability (HRV) indices, and electroencephalography (EEG) data were analyzed. Results. Children with IDA exhibited a specific clinical phenotype of ARA: predominance of the cyanotic type of attacks (70% vs. 50% in controls, p<0.05), higher frequency of paroxysms (3.3±1.5 per week), and pronounced post-attack asthenia. Neurophysiologically, this correlated with the predominance of theta activity on EEG (index 42±8%) and a decrease in the total power of the HRV spectrum (1245±310 ms²), reflecting functional immaturity of brainstem structures and exhaustion of autonomic reserves. Conclusion. The specificity of ARAs against the background of IDA is determined by metabolic disorders in the CNS, manifesting as vagotonia (cyanosis), slowing of cortical rhythms (theta activity), and decreased adaptive potential. The identified neurophysiological markers allow for the differentiation of "iron-dependent" paroxysms from epilepsy and substantiate pathogenetic therapy with iron preparations.

Maqola ma’lumotlari
MualliflarМаджидова Ёкутхон Набиевна, Адамбаев Зуфар Ибрагимович, Камолдинова Дилдора Бахтияровна
JurnalЖурнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research
NashriyotБухоро давлат тиббиёт институти
Nashr sanasi2026-06-22
Jild7
Son4
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

аффективные респираторные приступы, задержка дыхания, дети, железодефицитная анемия, клинические проявления, электроэнцефалография, вариабельность сердечного ритма, вегетативная нервная система, affective respiratory attacks, breath-holding spells, children, iron deficiency anemia, clinical manifestations, electroencephalography, heart rate variability, autonomic nervous system, affektiv nafas hujumlari, nafas tutish, bolalar, temir yetishmovchilik anemiyasi, klinik ko‘rinishlar, elektrotsefalografiya, yurak ritmini o‘zgaruvchanligi, vegetativ asab tizimi

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Iqtibos keltirish

APAМаджидова Ёкутхон Набиевна, Адамбаев Зуфар Ибрагимович, & Камолдинова Дилдора Бахтияровна (2026). SPECIFICS OF CLINICAL MANIFESTATIONS AND NEUROPHYSIOLOGICAL CORRELATES OF AFFECTIVE RESPIRATORY ATTACKS IN CHILDREN WITH IRON DEFICIENCY ANEMIA. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(4). https://tadqiqot.uz/index.php/neurology/article/view/14295
GOST (OAK)Маджидова Ёкутхон Набиевна, Адамбаев Зуфар Ибрагимович, Камолдинова Дилдора Бахтияровна SPECIFICS OF CLINICAL MANIFESTATIONS AND NEUROPHYSIOLOGICAL CORRELATES OF AFFECTIVE RESPIRATORY ATTACKS IN CHILDREN WITH IRON DEFICIENCY ANEMIA // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. – 2026. – T. 7, № 4.
MLAМаджидова Ёкутхон Набиевна, Адамбаев Зуфар Ибрагимович, and Камолдинова Дилдора Бахтияровна. “SPECIFICS OF CLINICAL MANIFESTATIONS AND NEUROPHYSIOLOGICAL CORRELATES OF AFFECTIVE RESPIRATORY ATTACKS IN CHILDREN WITH IRON DEFICIENCY ANEMIA.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(4), 2026. https://tadqiqot.uz/index.php/neurology/article/view/14295
ChicagoМаджидова Ёкутхон Набиевна, Адамбаев Зуфар Ибрагимович, and Камолдинова Дилдора Бахтияровна. “SPECIFICS OF CLINICAL MANIFESTATIONS AND NEUROPHYSIOLOGICAL CORRELATES OF AFFECTIVE RESPIRATORY ATTACKS IN CHILDREN WITH IRON DEFICIENCY ANEMIA.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(4) (2026). https://tadqiqot.uz/index.php/neurology/article/view/14295
HarvardМаджидова Ёкутхон Набиевна, Адамбаев Зуфар Ибрагимович, and Камолдинова Дилдора Бахтияровна (2026) ‘SPECIFICS OF CLINICAL MANIFESTATIONS AND NEUROPHYSIOLOGICAL CORRELATES OF AFFECTIVE RESPIRATORY ATTACKS IN CHILDREN WITH IRON DEFICIENCY ANEMIA’, Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 7(4). https://tadqiqot.uz/index.php/neurology/article/view/14295
BibTeX
@article{article2026,
  title = {SPECIFICS OF CLINICAL MANIFESTATIONS AND NEUROPHYSIOLOGICAL CORRELATES OF AFFECTIVE RESPIRATORY ATTACKS IN CHILDREN WITH IRON DEFICIENCY ANEMIA},
  author = {Маджидова Ёкутхон Набиевна and Адамбаев Зуфар Ибрагимович and Камолдинова Дилдора Бахтияровна},
  journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
  year = {2026},
  volume = {7},
  number = {4},
  url = {https://tadqiqot.uz/index.php/neurology/article/view/14295}
}

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