The article presents the results of a study of acid-dependent diseases (ADD) of the digestive system -gastroesophageal reflux disease, chronic gastritis and gastric ulcer and duodenal ulcer, reveals the main results of a study of genotyping ofpatients with ADD by the polymorphism C3435T of the MDR-l gene and CYP2C19:681G>A *2, polymorphism of the CYP2C19 gene and their relationship with the genotypes of the virulent Ice A gene of H.pylori infection, the frequency of their occurrence, the relationship and the influence of the genotypes of these genes of the pharmacokinetics of drugs of the patient and the infection on the effectiveness of eradication therapy in patients with ADD. The results of this study are of great importance in the selection ofpersonal dosage regimens for drugs, pharmacotherapy of CZD, which are based on genotyping of patients and H.pylori bacteria.
| Mualliflar | Мавлянов, И, Мусаева, Д, Mavlyanov, I, Musaeva, D |
|---|---|
| Jurnal | Тиббиёт ва спорт |
| Nashriyot | Ўзбекистон Миллий олимпия қўмитаси хузуридаги, Республика спорт тиббиёти илмий-амалий маркази |
| ISSN | 2181-998X |
| Nashr sanasi | 2026-06-15 |
| Son | 3 |
| Betlar | 92-102 |
| Til | Ingliz |
| Indeksga qo‘shilgan | 2026-08-27 |
полиморфизм С3435Т гена MDR-1, полиморфизм CYP2C19:681G>A*2 гена СУР2С19, кислотозависимые заболевания, гастроэзофагеальная рефлюксная болезнь, хронический гастрит, язвенная болезнь желудка и двенадцатиперстного кишечника, ген Ice A бактерии H.pylori, эрадикационная терапия, персонификация фармакотерапии, polymorphism C3435T of the MDR-1 gene, polymorphisms CYP2C19:681G>A*2 of the CYP2C19 gene, acid-dependent diseases, gastroesophageal reflux disease, chronic gastritis, gastric ulcer and duodenal ulcer, Ice A gene of H.pylori bacteria, eradication therapy, personification of pharmacotherapy, MDR-1 geni C3435T polimorfizmi, CYP2C19:681G>A*2 geni CYP2C19 polimorfizmi, kislota bilan bog'liq kasalliklar, gastroezofageal reflyuks kasalligi, surunkali gastrit, oshqozon yarasi va o'n ikki barmoqli ichak yarasi, H.pylori Ice A geni, eradikatsiya terapiyasi, shaxsiylashtirilgan farmakoterapiya
| APA | Мавлянов, И, Мусаева, Д, Mavlyanov, I, & Musaeva, D (2026). ACID-DEPENDENT DISEASES: A MODERN VIEW OF PHARMACOTHERAPY. Тиббиёт ва спорт, (3), 92-102. https://journal.sportmed.uz/index.php/medsport/article/view/124 |
|---|---|
| GOST (OAK) | Мавлянов, И va b. ACID-DEPENDENT DISEASES: A MODERN VIEW OF PHARMACOTHERAPY // Тиббиёт ва спорт. – 2026. – № 3. – P. 92-102. |
| MLA | Мавлянов, И, Мусаева, Д, Mavlyanov, I, and Musaeva, D. “ACID-DEPENDENT DISEASES: A MODERN VIEW OF PHARMACOTHERAPY.” Тиббиёт ва спорт, (3), 92-102, 2026. https://journal.sportmed.uz/index.php/medsport/article/view/124 |
| Chicago | Мавлянов, И, Мусаева, Д, Mavlyanov, I, and Musaeva, D. “ACID-DEPENDENT DISEASES: A MODERN VIEW OF PHARMACOTHERAPY.” Тиббиёт ва спорт, (3), 92-102 (2026). https://journal.sportmed.uz/index.php/medsport/article/view/124 |
| Harvard | Мавлянов, И, Мусаева, Д, Mavlyanov, I, and Musaeva, D (2026) ‘ACID-DEPENDENT DISEASES: A MODERN VIEW OF PHARMACOTHERAPY’, Тиббиёт ва спорт, (3), 92-102. https://journal.sportmed.uz/index.php/medsport/article/view/124 |
| BibTeX | @article{article2026,
title = {ACID-DEPENDENT DISEASES: A MODERN VIEW OF PHARMACOTHERAPY},
author = {Мавлянов, И and Мусаева, Д and Mavlyanov, I and Musaeva, D},
journal = {Тиббиёт ва спорт},
year = {2026},
number = {3},
pages = {92-102},
url = {https://journal.sportmed.uz/index.php/medsport/article/view/124}
} |
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