Clinical characteristics of hypoxic-ischemic encephalopathy in newborns depending on severity level

Xojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, Ochilova, Roziya, Ходжиметова, Шахноза, Гулямова, Муяссар, Турсунбаева, Феруза, Очилова, Розия, Xojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, Ochilova, Roziya

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-yil

Annotatsiya

Introduction. Hypoxic-ischemic encephalopathy (HIE) in newborns is one of the most severe forms of perinatal central nervous system injury. This condition develops as a result of oxygen deficiency and impaired cerebral circulation during the intrauterine period, childbirth, or early postnatal stage. The severity of the disease is directly related to the duration and depth of hypoxia, which affects the expression of clinical symptoms, prognosis, and treatment outcomes. Studying the course and clinical manifestations of HIE according to its severity plays an important role in early diagnosis, prognosis assessment, and the selection of effective therapeutic strategies. Objective of the study. To study the clinical characteristics of hypoxic-ischemic encephalopathy (HIE) in newborns depending on the degree of severity. Materials and methods. The study included 110 newborns diagnosed with hypoxic-ischemic encephalopathy who were treated in the Department of Neonatal Pathology at City Children's Hospital No. 5. Group 1 consisted of 39 infants with stage I HIE, Group 2 included 36 infants with stage II HIE, and Group 3 comprised 35 infants with stage III HIE. Diagnosis was established based on clinical examination, neurological assessment, and neurosonography of the newborns. Statistical analysis of the obtained data was carried out using Microsoft Excel 2010 and Statistica 6 software packages. Results. The study results demonstrated that in moderate and severe forms of hypoxic-ischemic encephalopathy, the diversity of clinical symptoms may be associated with the dynamics of morphological changes in brain structures. It should be noted that regardless of the degree, nature, depth, and extent of morphological and functional insufficiency of the central nervous system, the similarity and generality of clinical manifestations often make diagnosis challenging.

Maqola ma’lumotlari
MualliflarXojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, Ochilova, Roziya, Ходжиметова, Шахноза, Гулямова, Муяссар, Турсунбаева, Феруза, Очилова, Розия, Xojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, Ochilova, Roziya
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2025-12-24
Jild4
Son6
Betlar101-106
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-3612-2025-6-101-106
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-3612-2025-6-101-106 · Maqolaning asl sahifasi

Kalit so‘zlar

preterm infants, hypoxic-ischemic encephalopathy, severity, autonomic disorders, недоношенные новорожденные дети, степени тяжести, вегетативные нарушения, vaqtidan avval tugʼilgan bolalar, ogʼirlik darajasi, vegetativ buzilishlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAXojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, Ochilova, Roziya, Ходжиметова, Шахноза, Гулямова, Муяссар, Турсунбаева, Феруза, Очилова, Розия, Xojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, & Ochilova, Roziya (2025). CLINICAL CHARACTERISTICS OF HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEWBORNS DEPENDING ON SEVERITY LEVEL. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 101-106. https://doi.org/10.56121/2181-3612-2025-6-101-106
GOST (OAK)Xojimetova, Shaxnoza va b. CLINICAL CHARACTERISTICS OF HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEWBORNS DEPENDING ON SEVERITY LEVEL // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 6. – P. 101-106. – DOI: 10.56121/2181-3612-2025-6-101-106.
MLAXojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, Ochilova, Roziya, Ходжиметова, Шахноза, Гулямова, Муяссар, Турсунбаева, Феруза, Очилова, Розия, Xojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, and Ochilova, Roziya. “CLINICAL CHARACTERISTICS OF HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEWBORNS DEPENDING ON SEVERITY LEVEL.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 101-106, 2025. https://doi.org/10.56121/2181-3612-2025-6-101-106
ChicagoXojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, Ochilova, Roziya, Ходжиметова, Шахноза, Гулямова, Муяссар, Турсунбаева, Феруза, Очилова, Розия, Xojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, and Ochilova, Roziya. “CLINICAL CHARACTERISTICS OF HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEWBORNS DEPENDING ON SEVERITY LEVEL.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 101-106 (2025). https://doi.org/10.56121/2181-3612-2025-6-101-106
HarvardXojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, Ochilova, Roziya, Ходжиметова, Шахноза, Гулямова, Муяссар, Турсунбаева, Феруза, Очилова, Розия, Xojimetova, Shaxnoza, Gulyamova, Muyassar, Tursunboyeva, Feruza, and Ochilova, Roziya (2025) ‘CLINICAL CHARACTERISTICS OF HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEWBORNS DEPENDING ON SEVERITY LEVEL’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 101-106. https://doi.org/10.56121/2181-3612-2025-6-101-106
BibTeX
@article{xojimetovashaxnoza2025,
  title = {CLINICAL CHARACTERISTICS OF HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEWBORNS DEPENDING ON SEVERITY LEVEL},
  author = {Xojimetova, Shaxnoza and Gulyamova, Muyassar and Tursunboyeva, Feruza and Ochilova, Roziya and Ходжиметова, Шахноза and Гулямова, Муяссар and Турсунбаева, Феруза and Очилова, Розия and Xojimetova, Shaxnoza and Gulyamova, Muyassar and Tursunboyeva, Feruza and Ochilova, Roziya},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2025},
  volume = {4},
  number = {6},
  pages = {101-106},
  doi = {10.56121/2181-3612-2025-6-101-106},
  url = {https://doi.org/10.56121/2181-3612-2025-6-101-106}
}

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