This study investigated the anti-inflammatory effects of a biologically active supplement, Broccoli Extract (Brassica oleracea var. italica), containing indole-3-carbinol and sulforaphane, using a dextran-induced paw edema model in Wistar rats. The aim was to evaluate the efficacy of the broccoli extract in comparison with the reference anti-inflammatory drug Ibuklin 400 mg. Eighteen rats were divided into three groups: control, broccoli extract, and Ibuklin. Inflammation was induced by subplantar injection of 6% dextran solution, and anti-inflammatory activity was assessed by measuring paw volume at 1, 3, and 6 hours after administration of the test compounds. The results demonstrated that both interventions significantly reduced edema compared to the control group. At 3 hours post-induction, the mean paw volume increase was 1.40 ± 0.07 ml in the broccoli extract group (edema inhibition — 44%) and 1.25 ± 0.11 ml in the Ibuklin group (edema inhibition — 76%). These findings confirm that broccoli extract possesses notable anti-inflammatory activity and suggest its potential as a safe and effective dietary supplement for the prevention and management of inflammatory processes.
| Mualliflar | Boltaev, Mizrob M. |
|---|---|
| Jurnal | Товарлар кимёси ва халқ табобати |
| Nashriyot | Табобат академияси |
| ISSN | 2181-2977 |
| Nashr sanasi | 2026-03-21 |
| Jild | 5 |
| Son | 1 |
| Betlar | 224-235 |
| Til | Ingliz |
| Ilmiy soha | Farmatsevtika |
| DOI | 10.55475/jcgtm/vol5.iss1.2026.580 |
| Indeksga qo‘shilgan | 2026-08-26 |
DOI: 10.55475/jcgtm/vol5.iss1.2026.580 · Maqolaning asl sahifasi
broccoli, broccoli extract,, anti-inflammatory activity,, experimental inflammation model,, dextran-induced edema., брокколи,, экстракт брокколи,, противовоспалительное действие,, экспериментальная модель воспаления,, декстрановый отёк., brokkoli, brokkoli ekstrakti, yallig‘lanishga qarshi faollik,, eksperimental model,, dekstran bilan induktsiyalangan shish.
| APA | Boltaev, Mizrob M. (2026). EXPERIMENTAL EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROCCOLI EXTRACT. Товарлар кимёси ва халқ табобати, 5(1), 224-235. https://doi.org/10.55475/jcgtm/vol5.iss1.2026.580 |
|---|---|
| GOST (OAK) | Boltaev, Mizrob M. EXPERIMENTAL EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROCCOLI EXTRACT // Товарлар кимёси ва халқ табобати. – 2026. – T. 5, № 1. – P. 224-235. – DOI: 10.55475/jcgtm/vol5.iss1.2026.580. |
| MLA | Boltaev, Mizrob M. “EXPERIMENTAL EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROCCOLI EXTRACT.” Товарлар кимёси ва халқ табобати, 5(1), 224-235, 2026. https://doi.org/10.55475/jcgtm/vol5.iss1.2026.580 |
| Chicago | Boltaev, Mizrob M. “EXPERIMENTAL EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROCCOLI EXTRACT.” Товарлар кимёси ва халқ табобати, 5(1), 224-235 (2026). https://doi.org/10.55475/jcgtm/vol5.iss1.2026.580 |
| Harvard | Boltaev, Mizrob M (2026) ‘EXPERIMENTAL EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROCCOLI EXTRACT’, Товарлар кимёси ва халқ табобати, 5(1), 224-235. https://doi.org/10.55475/jcgtm/vol5.iss1.2026.580 |
| BibTeX | @article{boltaevmizrobm2026,
title = {EXPERIMENTAL EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROCCOLI EXTRACT},
author = {Boltaev, Mizrob M.},
journal = {Товарлар кимёси ва халқ табобати},
year = {2026},
volume = {5},
number = {1},
pages = {224-235},
doi = {10.55475/jcgtm/vol5.iss1.2026.580},
url = {https://doi.org/10.55475/jcgtm/vol5.iss1.2026.580}
} |
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