Systematic Review of Different Reperfusion Therapy Methods in Patients with ST-Elevation Acute Coronary Syndrome: Literature Review

Фозилов, Х, Атамуратов, Б, Fozilov, Xurshid, Atamuratov, Baxtiyor, Fozilov , Khurshid, Atamuratov, Bakhtiyor

O‘zbekiston кardiologiyasi · 2025-yil

Annotatsiya

Aim. Systematic analysis and comparison of different reperfusion therapy methods in patients with ST-elevation acute coronary syndrome (STEMI), including primary percutaneous coronary intervention (pPCI) and thrombolytic therapy (TLT), with emphasis on time factor and COVID-19 pandemic impact. Materials and methods. A systematic review of prospective randomized and observational studies comparing pPCI and TLT effectiveness in STEMI patients was conducted. Data from major international trials including DANAMI-2 (1572 patients), PRAGUE-2, STAT, GISSI, ISACS-STEMI COVID-19, meta-analyses of 23 studies, and modern global longitudinal strain assessment methods were analyzed. Results. Meta-analysis of 23 randomized studies showed statistically significant pPCI advantages over TLT: 30-day mortality 8.0% vs 13.7% (p=0.0003), recurrent infarction 3.8% vs 7.0% (p<0.05), revascularization need 5.7% vs 25.2% (p<0.001). "Golden hour" concept was confirmed. COVID-19 pandemic led to 19-30.5% reduction in STEMI presentations and worse prognosis. Conclusion. pPCI demonstrates statistically significant advantages over TLT, however method selection should consider time factor and technical availability. Modern global longitudinal strain assessment methods improve prognostic accuracy.

Maqola ma’lumotlari
MualliflarФозилов, Х, Атамуратов, Б, Fozilov, Xurshid, Atamuratov, Baxtiyor, Fozilov , Khurshid, Atamuratov, Bakhtiyor
JurnalO‘zbekiston кardiologiyasi
NashriyotЎзбекистон кардиологлар ассоциацияси
ISSN3060-4850
Nashr sanasi2025-09-30
Jild2
Son3
Betlar280-286
TilIngliz
Ilmiy sohaTibbiyot
DOI10.70626/cardiouz-2025-2-59
Indeksga qo‘shilgan2026-08-26

DOI: 10.70626/cardiouz-2025-2-59 · Maqolaning asl sahifasi

Kalit so‘zlar

acute coronary syndrome, reperfusion therapy, primary PCI, thrombolysis, global longitudinal strain, COVID-19, Острый коронарный синдром, реперфузионная терапия, первичное чрезкожное коронарное вмешательство, тромболизис, глобальная продольная деформация левого желудочка, COVID-19, O’tkir koronar sindrom, reperfuzion terapiya, birlamchi teri orqali koronar aralashuv, trombolizis, chap qorincha global bo’ylama deformatsiyasi, COVID-19

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAФозилов, Х, Атамуратов, Б, Fozilov, Xurshid, Atamuratov, Baxtiyor, Fozilov , Khurshid, & Atamuratov, Bakhtiyor (2025). Systematic Review of Different Reperfusion Therapy Methods in Patients with ST-Elevation Acute Coronary Syndrome: Literature Review. O‘zbekiston кardiologiyasi, 2(3), 280-286. https://doi.org/10.70626/cardiouz-2025-2-59
GOST (OAK)Фозилов, Х va b. Systematic Review of Different Reperfusion Therapy Methods in Patients with ST-Elevation Acute Coronary Syndrome: Literature Review // O‘zbekiston кardiologiyasi. – 2025. – T. 2, № 3. – P. 280-286. – DOI: 10.70626/cardiouz-2025-2-59.
MLAФозилов, Х, Атамуратов, Б, Fozilov, Xurshid, Atamuratov, Baxtiyor, Fozilov , Khurshid, and Atamuratov, Bakhtiyor. “Systematic Review of Different Reperfusion Therapy Methods in Patients with ST-Elevation Acute Coronary Syndrome: Literature Review.” O‘zbekiston кardiologiyasi, 2(3), 280-286, 2025. https://doi.org/10.70626/cardiouz-2025-2-59
ChicagoФозилов, Х, Атамуратов, Б, Fozilov, Xurshid, Atamuratov, Baxtiyor, Fozilov , Khurshid, and Atamuratov, Bakhtiyor. “Systematic Review of Different Reperfusion Therapy Methods in Patients with ST-Elevation Acute Coronary Syndrome: Literature Review.” O‘zbekiston кardiologiyasi, 2(3), 280-286 (2025). https://doi.org/10.70626/cardiouz-2025-2-59
HarvardФозилов, Х, Атамуратов, Б, Fozilov, Xurshid, Atamuratov, Baxtiyor, Fozilov , Khurshid, and Atamuratov, Bakhtiyor (2025) ‘Systematic Review of Different Reperfusion Therapy Methods in Patients with ST-Elevation Acute Coronary Syndrome: Literature Review’, O‘zbekiston кardiologiyasi, 2(3), 280-286. https://doi.org/10.70626/cardiouz-2025-2-59
BibTeX
@article{article2025,
  title = {Systematic Review of Different Reperfusion Therapy Methods in Patients with ST-Elevation Acute Coronary Syndrome: Literature Review},
  author = {Фозилов, Х and Атамуратов, Б and Fozilov, Xurshid and Atamuratov, Baxtiyor and Fozilov , Khurshid and Atamuratov, Bakhtiyor},
  journal = {O‘zbekiston кardiologiyasi},
  year = {2025},
  volume = {2},
  number = {3},
  pages = {280-286},
  doi = {10.70626/cardiouz-2025-2-59},
  url = {https://doi.org/10.70626/cardiouz-2025-2-59}
}

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